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Abstracts. PHYTOPHARM 2017
analyzed using both FTIR and HPLC methods and the obtained HPLC fingerprints of each samples were compared with the reference Mastic gum.
Among 12 mastic samples only two samples showed a little similarity with original mastic in fingerprints, 10 others are similar with each other but completely different with mastic. They are also different from other resins we analyzed.
None of our samples complied with the original mastic. Only two products based on the relative
similarity to mastic HPLC as well as the appearance and smell seemed to be natural substances. Although the ten other samples in terms of appearance completely seemed to be synthetic compounds, but because of the large number of similar synthetic materials we were unable to determine exactly what they are so judgment about the main nature of them needs more studies.
MEDICINAL PLANTS FOR RADIATION PROCTITIS ACCORDING TO PERSIAN MEDICINE VIEWPOINT
© Narjes Gorji1, Reihaneh Moeini1, H Rezaeizadeh2, Tayebeh Taheripanah3
1 Traditional Medicine and History of Medical Sciences Research Center, Babol University of Medical Sciences, Babol, Iran;
2 Persian Medicine & Pharmacy Research Center, Faculty of traditional Medicine, Tehran university of medical science, Tehran, Iran;
3 Aja university of medical science, Tehran, Iran
Proctitis is common adverse effect of radiotherapy for cancers of pelvic organs that has no perfect treatment [1]. On the other hand traditional medicines are good platforms for researches about unanswered questions in modern medicine. Persian Medicine has introduced many medicinal herbs for treatment of intestinal ulcers and inflammations that may be helpful also in radiation proctitis (RP) [2-5].
In this study PM reference books were reviewed and medicinal plants for treatment of ulcers and inflammation of intestine were extracted and then Google scholar, Scopus, PubMed and Web of science databases were searched for new evidences about their effects and mechanism of action.
Punicagranatum L., Althaea spp, Acasia arabica, Plantago major L, Commiphora mukul. L, Pistaci alentiscus and Terminalia chebulaare are some of plants from PM literatures for ulcer and inflammation of intestine [2-5].
Many of these herbs have immunomodulatory, antioxidant, anti-ulcerogenic and antibacterial properties and also they have shown ability to decrease Interleukin-2, Interleukin-4, nuclear factor-KB, nitric oxide and cyclooxygenase-2 [6-8].
PM introduced many herbs to treat intestinal inflammation in the form of oral drug and enema. Some
of these are laxatives, but some others have anti-diarrheal effect [9] and can inhibit bleeding.
In vivo and in vitro studies have shown these herbs have potential to affect some mechanism of radiation proctitis generation [10] but studies about medicinal herbs in treatment of RP are limited.
On the other hand use of these plants due to high levels of antioxidants can be challenging.
References:
1. Halper EC, Wazer DE, Perez CA, 2013. Chapter 97: 1807.
2. Kermani N-i-I. RICM. 1387.
3. Arzani MA. RICM. 1387.
4. Azam Kan M. RICM. 1387.
5. Aghili MH. 2009. http://aqlibrary.org/UserFiles/File/ makhzan.pdf.
6. Farzaei MH, Shams-Ardekani MR, Abbasabadi Z, Rahimi R. 2013. Gastroenterology. 2013. 12.
7. Vigo E, Cepeda A, Gualillo O, Perez-Fernandez R. 2005. Journal of pharmacy and pharmacology. 57. 383-391.
8. Abd El-Mawla AM, Osman HE, 2011. Pharmacognosy Res. 3(2):114-121.
9. Qnais EY, Elokda AS, Abu Ghalyun YY, Abdulla FA, 2007. Pharmaceutical Biology. 45(9):715-720.
10. Cheon J H, Kim JS, Kim JM. 2006. Inflammatory Bowel Diseases. 12(12):1152-1161.
Obzory po kliniceskoj farmacologii i lekarstvennoj terapii [Reviews of clinical pharmacology and drug therapy]
vol. 15/2017/suppLement 1
