CC BY
24
^smuóS
""«и 4 SFMF.Y MEDICAL UNIVERSITY ■
Received: 8 May 2019 / Accepted: 22 June 2019 / Published online: 30 August 2019 UDC 616.89
A PROPOSAL OF 4 CRITERIA FOR FUTURE COLLABORATIVE RESEARCH BETWEEN KAZAKHSTAN AND JAPAN: SUGGESTIONS FOCUSING ON SEMEY, KOCHI, HIROSHIMA AND SHIMANE
Ken Inoue1, Nailya Zh. Chaizhunussova2, Yoshihiro Noso3, Nobuo Takeichi4, Sadayuki Hashioka5, Haruo Takeshita5, Yasuyuki Fujita5, Madina М. Apbassova2, Dariya М. Shabdarbayeva2, Gulnar А. Berekenova2, Masaharu Hoshi6, Shotai Kobayashi5, Yersin T. Zhunussov2
1 Kochi University, Kochi, Japan;
2 «Semey Medical University» NJSC, Semey city, Republic of Kazakhstan;
3 Hiroshima International University, Hiroshima, Japan;
4 Takeichi Clinic, Hiroshima, Japan;
5 Shimane University, Shimane, Japan;
6 Hiroshima University, Hiroshima, Japan.
Abstract
Collaborative research is based on 4 criteria that will be conducted in the future between Semey Medical University and Kochi University, Hiroshima University, Hiroshima International University and Shimane University to assess the social contribution of these studies.
The proposed material describes the social contribution made by the authors, both locally and internationally. Four criteria suggest what kind of contribution can be made. Based on these criteria, this material touches on the discussion of future collaborative research, that is, joint research between the "Republic of Kazakhstan and Japan", between the city of Semey and Kochi, Hiroshima, Shimane, 'also between' SMU and Kochi University, Hiroshima University, Hiroshima International University, Shimane University'. The four criteria are "1. Collaboration between public health and clinical medicine: testing suicide prevention measures, stress studies, epidemiological and biological studies among primary and secondary school students, and studies based on population diagnostics", "2. Research from the perspective of clinical medicine: psychiatry, surgery and therapy, "3. Basic medical research. Collaboration between basic medicine and clinical medicine: Genetic research; research in basic medicine and clinical medicine focused on microglia; subnuclear physics and the influence of radiation (including aspects from the point of view of physics)", and "4. Social Contribution: Local and International Contribution." Adhering to this, the level of research work of each university in particular will advance, and at the same time, the level of skills in conducting joint research.
Keywords: new research, criteria, social contribution, Kazakhstan, Japan.
Резюме
4 КРИТЕРИЯ, ПРЕДЛАГАЕМЫЕ ДЛЯ БУДУЩЕЙ КОЛЛАБОРАЦИИ В ОБЛАСТИ ИССЛЕДОВАНИЙ МЕЖДУ КАЗАХСТАНОМ И ЯПОНИЕЙ: ПРЕДЛОЖЕНИЯ, СФОКУСИРОВАННЫЕ НА СЕМЕЙ, КОЧИ,
ХИРОСИМА И ШИМАНЕ
Кен Иноуэ1, Наиля Ж. Чайжунусова 2, Йошихиро Носо3, Нобуо Такейчи4, Садаюки Хашиока5, Харуо Такешита5, Ясуюки Фудзита5, Мадина М. Апбасова2, Дарья М. Шабдарбаева2, Гульнар А. Берекенова2, Масахару Хоши6, Шотай Кабаяши5, Ерсин Т. Жунусов2
1 Университет Кочи, г. Кочи, Япония;
2 НАО «Медицинский университет Семей», г. Семей, Республика Казахстан;
3 Хиросимский Интернациональный Университет, г. Хиросима, Япония;
4 Клиника Такеичи, г. Хиросима, Япония;
5 Университет Симане, г. Шимане, Япония;
6 Университет Хиросимы, г. Хиросима, Япония.
Коллаборативные исследование основаны на 4 критериях, которые будут проведены в будущем между Semey Medical University и Kochi University, Hiroshima University, Hiroshima International University, а также Shimane University, для оценки социального вклада этих исследований.
Наука и Здравоохранение, 2019, 4 (Т.21)_Медицинское образование
Предложенный материал описывает социальный вклад внесенный авторами, как в локальном, так и в международном масштабе. Четыре критерия предполагают, какой же вклад может быть внесен.
Основываясь на этих критериях, данный материал затрагивает в обсуждении будущие коллаборативные исследования, то есть совместные исследования, между "Республикой Казахстан и Японией", между городом Семей и Кочи, Хиросима, Шимане', также между 'SMU и Kochi University, Hiroshima University, Hiroshima International University, Shimane University'.
Четырьмя критериями стали "1. Коллаборация между сферой общественного здоровья и клинической медициной: тестирование мер по предотвращению суицида, исследования касающиеся стресса, эпидемиологические и биологические исследования среди учащихся младшей и средней ступени школы, и исследования, базирующиеся на диагностике населения", "2. Исследования с перспективы клинической медицины: психиатрия, хирургия и терапия", "3. Базисное медицинское исследование. Коллаборация между базовой медициной и клинической медициной: Генетические исследования; исследования в базовой медицине и клинической медицине, сфокусированные на микроглии; субъядерная физика и влияние радиации (включая аспекты с точки зрения физики)", и "4. Социальный вклад: локальный и международный вклад".
Придерживаясь этого, продвинется уровень исследовательских работ каждого университета в частности, а вместе с тем, и уровень умений ведения совместных исследований.
Ключевые слова: новые исследования, критерии, социальный вклад, Казахстан, Япония.
Туйшдеме
КАЗАХСТАН МЕН ЖАПОНИЯ ЕЛДЕР1 АРАСЫНДАГЫ ЗЕРТТЕУЛЕРД1 4 КРИТЕРИЙ БОЙЫНША БОЛАШАК КОЛЛАБОРАЦИЯСЫ ¥СЫНЫЛАДЫ: ТОГЫСТЫРЫЛГАН СЕМЕЙ, КОЧИ, ХИРОСИМА Ж9НЕ ШИМАНЕ
Кен Иноуэ1, Наиля Ж. Чайжунусова2, Йошихиро Носо3, Нобуо Такейчи4, Садаюки Хашиока5, Харуо Такешита5, Ясуюки Фудзита5, Мадина М. Апбасова2, Дарья М. Шабдарбаева2, Гульнар А. Берекенова2, Масахару Хоши6, Шотай Кабаяши5, Журсун Т. Жунусов2
1 Кочи университету Кочи к-, Жапония;
2 КеАК «Семей медициналык университет», Семей к-, Казакстан Республикасы;
3 Хиросима Халыкаралык университетi, Хиросима к-, Япония;
4 Такеичи клиникасы, Хиросима к-, Япония;
5 Симане университету Шимане к-, Япония;
6 Хиросима университету Хиросима к-, Япония.
Болашакта Семей медицина университету Кочи университету Хиросима университету Хиросима халыкаралык университет жэне симане университет араларында ететЫ зерттеулердщ 8леуметтiк корына бага беру Yшiн коллаборативтi зерттеулер 4 кретерилерге непзделген.
¥сынылган материал авторлармен енпзтген 8леуметтiк корды, соымен катар халыкаралык келемде сипаттайды.
Терт кретерии кандай кор енгiзiлетiнiн болжайды. Осы кретерилерге непзделе отырып ^азакстан Республикасы ж8не Жапония елiмен оныщ iшiнде Семей ж8не Кочи, Хиросима калалары арасында берiлген материал болашак зерттеулердi талкылайды№ Терт кретериге: 1. ^ам денсаулыгы мен клиникалык медицина арасындагы коллабрация, суицидп алдын алу Yшiн тесттеу, суицидке катысты зерттеулер, мектептщ теменп ж8не орта буын арасындагы окушыларга эпидемиологиялык ж8не биологиялык зерттеулер, т^ындардыщ диагностика негiзделген зерттеулер. 2. Клиникалык медицинаныщ перспективалык зерттеулерi. Психиатрия, хирургия, терапия. 3. Непзп медициналык зерттеу. Клиникалык медицина арасындагы колабрация. Генетикалык зерттеу. Негiзгi медицина ж8не клиникалык медицина зерттеулеру ядролык физика, радиация ыкпалы, (физикалык кезкарас аспектiлерi). 4. Элеуметш кор, локалды ж8не халыкаралык кор.
Жогарыда айтылгандарды устана отырып 8рбiр университеттщ зерттеу жумыстары сонымен катар бiрлескен зерттеулердi жYргiзудi бту керек дечгейлерi артады.
I» SEMEY MEDICAL UNIVERSITY
^smuóS
""«и 4 SFMF.Y MEDICAL UNIVERSITY ■
Библиографическая ссылка:
Кен Иноуэ, Чайжунусова Н.Ж., Йошихиро Носо, Нобуо Такейчи, Садаюки Хашиока, Харуо Такешита, Ясуюки Фудзита, Апбасова М.М., Шабдарбаева Д.М., Берекенова Г.А., Маcахару Хоши, Шотай Кабаяши, Жунусов Е.Т. 4 критерия, предлагаемые для будущей коллаборации в области исследований между Казахстаном и Японией: предложения, сфокусированные на Семей, Кочи, Хиросима и Шимане // Наука и Здравоохранение. 2019. 4 (Т.21). С. 106-112.
Ken Inoue, Chaizhunussova N.Zh., Yoshihiro Noso, Nobuo Takeichi, Sadayuki Hashioka, Haruo Takeshita, Yasuyuki Fujita, Apbassova M.M., Shabdarbayeva D.M., Berekenova G.A., Masaharu Hoshi, Shotai Kobayashi, Zhunussov Ye.T. A proposal of 4 criteria for future collaborative research between Kazakhstan and Japan: Suggestions focusing on Semey, Kochi, Hiroshima and Shimane // Nauka i Zdravookhranenie [Science & Healthcare]. 2019, (Vol.21) 4, pp. 106-112.
Кен Иноуэ, Чайжунусова Н.Ж., Йошихиро Носо, Нобуо Такейчи, Садаюки Хашиока, Харуо Такешита, Ясуюки Фудзита, Апбасова М.М., Шабдарбаева Д.М., Берекенова Г.А., Масахару Хоши, Шотай Кабаяши, Жунусов Е.Т. ^азакстан мен Жапония елдерi арасындагы зерттеулердi 4 критерий бойынша болашак коллаборациясы усынылады: тогыстырылган Семей, Кочи, Хиросима жэне Шимане // Гылым жэне Денсаулык сактау. 2019. 4 (Т.21). Б. 106-112.
Introduction
Semey State Medical University (denoted here as Semey Medical University: SMU) concluded an agreement with several Japanese universities (Kochi University, Hiroshima University, and Shimane University) [1]. Independent studies at SMU several years prior were related to radiation [1-2]. Over a 3-year-period, studies examined aspects of radiation [5,6] and they examined radiation from the perspective of clinical medicine [7-9] and basic medicine and public health [5,11]. SMU needs to endeavor to conduct regional studies of the Republic of Kazakhstan (like Semey), studies of Kazakhstan as a whole, and global studies on its own or jointly with other institutions. SMU also needs to conduct further studies in basic medicine and clinical medicine on its own or jointly with other institutions.
The Japanese authors of this work previously reported on collaboration with SMU [1,3,6,12-9]. Research into areas in which the Japanese authors of this work specialize could be conducted jointly with SMU. That could contribute to academic advancement in Semey and other parts of the Republic of Kazakhstan. In addition, staff of SMU could lecture at and conduct joint research with Japanese universities. This could further enhance joint research conducted between Japanese universities and SMU.
Research in which the Japanese authors of this work specialize is described here, along with its local and international contributions. This work also examines future collaborative research between Semey and Japan and future collaborative research between SMU and Kochi University, Hiroshima University, Hiroshima International University, and Shimane University.
Methods
This was a descriptive study.
Method of selection of study participants
This work systematically summarized research that the Japanese authors of this work are conducting or have conducted. Local and international contributions made by the authors are also summarized. This work describes new forms of collaboration between 'the Republic of Kazakhstan and Japan', between 'Semey and Kochi, Hiroshima, and Shimane', and between 'SMU and Kochi University, Hiroshima University, Hiroshima International University,
and Shimane University'. This work also describes further collaborative social contributions.
Data collection
Research that is or has been conducted by the Japanese authors of this work has been identified, and reports of social efforts have been collected.
Data presentation
1. The Introduction describes previous studies that have been conducted mainly with SMU.
2. Research that is being or has been conducted by the Japanese authors of this work and social efforts have been described in terms of 4 criteria: "1. Collaboration between public health and clinical medicine", "2. Studies from the perspective of clinical medicine", "3. Basic medical research. Collaboration between basic medicine and clinical medicine", and "4. Social contributions: Local and international contributions".
3. Based on the implications of (1) and (2), new forms of collaborative research between 'Semey and Japan' and between 'SMU and Kochi University, Hiroshima University, Hiroshima International University, and Shimane University' have been examined. Various contributions related to that research have also been examined.
Data analysis
A descriptive study was conducted with a focus on (1) and (2) described in 4. Data presentation in the Methods. (1) and (2) were analyzed in detail, and (3) was performed.
Ethical considerations
There is no personal information in this study or paper.
Results
1. Collaboration between public health and clinical medicine
1-1 Examining suicide prevention measures
Research on suicide in Japan by the current authors provided insights from several perspectives.
Specific suicide prevention measures have been proposed based on a study of motives for suicide in light of suicide statistics for Japan as a whole [16]. Proposed suicide prevention measures have been examined in several Japanese prefectures [17,18].
Factors related to suicide have been examined economically, socially, and biologically [19-24].
Наука и Здравоохранение, 2019, 4 (Т.21)
Медицинское образование
*^smu 65
, "ibj" SEMF.V МИЖ-Л1. UNIVKRSITY
1-2 Stress-related research
A collaborative study examined psychological measures and salivary cortisol and amylase in order to promptly detect and prevent anxiety and stress in medical personnel [25]. A study on leave from work for mental reasons suggested the need to further enhance return to work programs [26].
1-3 Epidemiological and biological studies of elementary and middle school students
An epidemiological study of elementary and middle school students reported their mood upon waking and electronic device use [18]. Another study suggested that lifestyle and serum cortisol were related [20]. Yet another study offered a view of "gaming disorder", which has become an international issue [21].
1-4 Studies based on screening and studies of local residents
A study conducted eye screening over a set period in an area of a prefecture, and it detected glaucoma early on [3]. The burden of caring for the elderly is a social issue in Japan. A study suggested that family caregivers need a respite [22].
2. Studies from the perspective of clinical medicine
2-1 Psychiatry
One study of panic disorder discussed the condition in light of whether or not agoraphobia was also present [23], another examined the relationship between the age of onset of panic attacks and the number of symptoms and a family history of a psychiatric disorder among first-degree relatives [24], and yet another examined potential characteristics of being at risk of suicide [25].
A study compared the characteristics of salivary amylase in relation to schizophrenia and control [26].
2-2 Surgery
Several studies in clinical medicine have reported on cancer due to the effects of radiation and surgical options [27,28].
2-3 Internal medicine
A study reported on the importance of screening for early detection of cancer due to the effects of radiation (thyroid cancer in particular) [29]. A neurological study of conditions such as stroke has also been reported [30].
3. Basic medical research. Collaboration between basic medicine and clinical medicine
3-1 Genetic research
Numerous studies have reported on deoxyribonuclease (DNase) [31,32,42,33,44,45,34]. Several studies have reported on the relationship between levels of zinc and iron in the blood and single nucleotide polymorphisms (SNPs) [35,6].
3-2 Research in basic medicine and clinical medicine focusing on microglia
Studies in basic medicine and clinical medicine have examined microglia [7-40,36,38]. Although some studies emphasized basic medicine [47,50,51,53,10,11,12], others provided strong implications for clinical medicine [13,14,15,16,17].
3-3 Particle science and the effects of radiation (including aspects of physics)
A study at HIMAC microdosimetrically evaluated secondary particles in a phantom produced by carbon 290 MeV/nucleon ions [55]. A study also reported on contamination at the Fukushima Dai-ichi Nuclear Power
Plant [6]. Yet another study yielded suggestions regarding radioactive cesium as a result of the Fukushima Dai-ichi Nuclear Power Plant accident [52,61].
4. Social contributions
4-1 Local contributions
The Japanese authors of this work have engaged in several efforts related to the Republic of Kazakhstan. Exchange students from Kochi University to the Republic of Kazakhstan and their faculty advisor (one of the authors of this work) visited the deputy mayor of Kochi City in Kochi City Hall to describe the purpose and background of the exchange [62,47]. Studies recommended concluding agreements on exchanges between Kochi University and Kazakh universities (academic exchanges and student exchanges) [57,39]. Efforts by the government, nongovernmental organizations (NGOs), and private organizations and collaborative efforts in relevant areas by relevant agencies truly represent community-wide efforts. [50-56].
The Japanese authors of this work are also lecturing on the Republic of Kazakhstan.
4-2 International contributions
The Japanese authors of this work have visited the Kazakh embassy in Japan, the Japanese embassy in Kazakhstan, and the international program center in Astana. The authors have promoted agreements on exchanges and sought cooperation from Kazakh universities and agencies to conduct joint research [5865].
Discussion
This work has described studies conducted by the authors and social efforts with an eye toward future collaboration with the Republic of Kazakhstan (mainly with Semey and SMU). SMU has endeavored to conduct further research in public health over the past few years. The current authors have previously studied "collaboration between public health and clinical medicine" from several perspectives. The most prominent characteristics of public health research conducted by the current authors are that it benefits society and that it discusses public health in in terms of social medicine and clinical medicine. SMU previously emphasized clinical medicine, though the current authors have approaches in multiple areas, i.e. psychiatry, surgery, and internal medicine. Various courses in basic medicine at SMU continue to conduct experiments as part of basic medical research. The current authors conduct basic medical research but focus on collaborative studies in basic medicine and clinical medicine. Social contributions made by the current authors are both local and international contributions.
Studies over the past few years have suggested the importance of collaborative research and social contributions [45-46].
Conclusion
The current work has suggested 4 criteria for future collaborative research between Semey and Kochi, Hiroshima, and Shimane, i.e. between SMU and Kochi University, Hiroshima University, Hiroshima International University, and Shimane University. In specific terms, these criteria are:
"1. Collaboration between public health and clinical medicine",
*^smu 65
ií) SFMF.Y MEDICAL UNIVERSITY ■
"2. Studies from the perspective of clinical medicine: Psychiatry, surgery, and internal medicine",
"3. Basic medical research. Collaboration between basic medicine and clinical medicine: Genetic research, research in basic medicine and clinical medicine focusing on microglia, and particle science and the effects of radiation (including aspects of physics)", and
"4. Social contributions".
That research can be conducted at SMU or its affiliated hospitals, and novel studies will be conducted. SMU and Kochi University, Hiroshima University, Hiroshima International University, and Shimane University can conduct joint research, implement social efforts, and continue conducting studies in accordance with the 4 criteria.
Doing so should improve the level of research at each university and improve research capabilities through joint research.
That research could be extended within the framework of Semey, Kochi, Hiroshima, and Shimane, and that could lead to advances in research in the Republic of Kazakhstan and Japan.
Conflict of interest: None.
Acknowledgements
We wish to thank Chieko Kobatake (Hiroshima Semipalatinsk Project, Hiroshima, Japan), Naoyuki Kanki (Ichikawa Japanese language school, Almaty, Kazakhstan), and Zarina Mendygazyeva (Ichikawa Japanese language school, Almaty, Kazakhstan) for their valuable comments or cooperation.
Author's contributions: KI, NC, YN, NT, SH, HT, YF, MA, DS, MH, SK and YZ designed the study and discussed comments of this study. KI got comments or cooperation from CK, NK, and ZM. KI, NC, YN, NT, SH, HT, YF, MA, DS, MH, SK and YZ read and approved the report for submission.
Funding: None.
References:
1. Apsalikov B., Manambaeva Z., Ospanov E., Massabayeva M., Zhabagin K., Zhagiparova Z., et al. BRCA1 and TP53 Gene-Mutations: Family Predisposition and Radioecological Risk of Developing Breast Cancer // Asian Pacific Journal of Cancer Prevention. 2016; 17(8): pp.4059-4062.
2. Aketayeva A., Khamidullina Z., Akhmetova Z., Baubekova A., Khismetova Z., Dudnik Y., et al. Diagnosis and Treatment of Female Infertility Is One of the Major Problems in Modern Gynecology // Iranian Journal of Public Health. 2018; 47(1): pp.135-137.
3. Abe M., Inoue K., Tanito M., Ohira A., Yamamoto Y., Fujita Y. Epidemiological Study of Glaucoma in Residents of a Rural Community: Analysis of Data Obtained from Resident Health Screenings in the Town of Sakurae in Shimane Prefecture, Japan // International Medical Journal. 2014; 21(2): pp.196-200.
4. Bokura H., Kobayashi S., Yamaguchi S., Iijima K., Nagai A., Toyoda G., et al. Silent brain infarction and subcortical white matter lesions increase the risk of stroke and mortality: a prospective cohort study // Journal of Stroke and Cerebrovascular Diseases. 2006; 15(2): pp.57-63.
5. Chaizhunusova N., Madiyeva M., Tanaka K., Hoshi M., Kawano N., Noso Y., et al. Cytogenetic abnormalities of the descendants of permanent residents of heavily contaminated East Kazakhstan // Radiation and
Environmental Biophysics. 2017; 56(4): pp.337-343.
6. Endo S., Takada M., Onizuka Y., Tanaka K., Maeda N., Ishikawa M., et al. Microdosimetric evaluation of secondary particles in a phantom produced by carbon 290 MeV/nucleon ions at HIMAC // Journal of Radiation Research. 2007; 48(5): pp.397-406.
7. Fujihara J., Yasuda T., Kimura-Kataoka K., Takinami Y., Nagao M., Takeshita H. Association of SNPs in genes encoding zinc transporters on blood zinc levels in humans // Legal Medicine. 2018; 30: pp.28-33.
8. Fujihara J., Yasuda T., Kimura-Kataoka K., Takeshita H. Association of SNPs in transferrin and transferrin receptor genes with blood iron levels in human // Legal Medicine. 2019; 36: pp.17-20.
9. Goremykina M., Gerdt A., Ibraev Y., Kalmakbayev B., Dyakonov K., Skinder O., et al. A Rare Case of Nasal NK/T-Cell Lymphoma in a Kazakh Man // The Israel Medical Association Journal. 2018; 20(12): pp.790-791
10. Hashioka S., Monji A., Ueda T., Kanba S., Nakanishi H. Amyloid-beta fibril formation is not necessarily required for microglial activation by the peptides // Neurochemistry International. 2005; 47(5): pp.369-376.
11. Hashioka S., Han Y.H., Fujii S., Kato T., Monji A., Utsumi H., et al. Phospholipids modulate superoxide and nitric oxide production by lipopolysaccharide and phorbol 12-myristate-13-acetate-activated microglia // Neurochemistry International. 2007; 50(3): pp.499-506.
12. Hashioka S., Han Y.H., Fujii S., Kato T., Monji A., Utsumi H., et al. Phosphatidylserine and phosphatidylcholine-containing liposomes inhibit amyloid beta and interferon-gamma-induced microglial activation // Free Radical Biology & Medicine. 2007; 42(7): pp.945-954.
13. Hashioka S., Klegeris A., Schwab C., McGeer P.L. Interferon-gamma-dependent cytotoxic activation of human astrocytes and astrocytoma cells // Neurobiology of Aging. 2009; 30(12): pp.1924-1935.
14. Hashioka S., Klegeris A., McGeer P.L. Inhibition of human astrocyte and microglia neurotoxicity by calcium channel blockers // Neuropharmacology. 2012; 63(4): pp.685-691.
15. Hashioka S., Klegeris A., Monji A., Kato T., Sawada M., McGeer P.L., et al. Antidepressants inhibit interferon-gamma-induced microglial production of IL-6 and nitric oxide // Experimental Neurology. 2007; 206(1): pp.33-42.
16. Hashioka S., McGeer P.L., Monji A., Kanba S. Anti-inflammatory effects of antidepressants: possibilities for preventives against Alzheimer's disease // Central Nervous System Agents in Medicinal Chemistry. 2009; 9(1): pp.1219.
17. Hashioka S., McGeer P.L., Miyaoka T., Wake R., Horiguchi J. Can inhibition of microglial activation cure schizophrenia? // Schizophrenia Research. 2015; 168(1-2): pp.583-584.
18. Inoue K., Chaizhunusova N., Parnytska O., Noso Y., Bitebayeva D., Sharapiyeva A., et al. A Comparison of Specific Efforts that Japan and Russia Should Endeavor to Undertake: In Light of Different Population Proportions by Age Group in Countries with the World's Largest Populations // International Medical Journal. 2019; 26(1): pp.28-29.
19. Inoue K., Chaizhunusova N., Hoshi M., Noso Y., Takeichi N., Nurgul O., et al. The mutual development of
Наука и Здравоохранение, 2019, 4 (Т.21)
Медицинское образование
*^smu 65
, "ibj" SEMEY МГОТСЛ! UNIVERSITY
universities and areas in Semey and three prefectures in Japan: Continuing educational and research activities, clinical practice, and cooperation and new proposals based on our history with international exchanges // Science & Healthcare. 2018; 6: pp.163-168.
20. Inoue K., Horiguchi J., Hashioka S., Takeshita H., Fujita Y., Nurgul O., et al. A systematic summary of "social anxiety disorder^' and the need for detailed examination of approaches in the future // Journal of St Marianna Medical Institute. 2019; 19; pp.32-35.
21. Inoue K., Hashioka S., Chaizhunusova N., Nurgul O., Timur M., Zhanat S., et al. Discussion of several aspects of panic disorder and further research of that disorder in the future // Journal of St Marianna Medical Institute. 2019; 19; pp.29-31.
22. Inoue K., Tanii H., Mori T., Nishimura Y., Hara N., Nishida A., et al. Discussion of preventive measures against the increase of suicide among males in Japan // The American Journal of Forensic Medicine and Pathology. 2011; 32(4): pp.e19-20.
23. Inoue K., Tanii H., Abe S., Nata M., Nishimura Y., Nishida A., et al. Causative factors as cues for addressing the rapid increase in suicide in Mie Prefecture, Japan: comparison of trends between 1996-2002 and 1989-1995 // Psychiatry and Clinical Neurosciences. 2006; 60(6): pp.736745.
24. Inoue K., Imaoka M., Nakanishi T., Wada K. The Importance of Continuing to Implement Additional Suicide Prevention Measures in Shimane Prefecture // International Medical Journal. 2013; 20(1): pp.6.
25. Inoue K., Tanii H., Kaiya H., Abe S., Nishimura Y., Masaki M., et al. The correlation between unemployment and suicide rates in Japan between 1978 and 2004 // Legal Medicine. 2007; 9(3): pp.139-142.
26. Inoue K. Significant correlation of the change in the divorce rate with the suicide rate in Japan from 1992 to 2004 // American Journal of Forensic Medicine and Pathology. 2009; 30(3): pp.311.
27. Inoue K., Fukunaga T., Okazaki Y. Study of an economic issue as a possible indicator of suicide risk: a discussion of stock prices and suicide // Journal of Forensic Sciences. 2012; 57(3): pp.783-785.
28. Inoue K., Fukunaga T., Fujita Y., Okazaki Y. Can the Number of New Housing Starts Serve as an Indicator of Suicide Trends in Japan?: Exploring Potential Indicators to Prevent Suicides // International Medical Journal. 2012; 19(4): pp.297-298.
29. Inoue K., Nishimura Y., Fujita Y., Ono Y., Fukunaga T. The relationship between suicide and five climate issues in a large-scale and long-term study in Japan // The West Indian Medical Journal. 2012; 61(5): pp.532-537.
30. Inoue K., Fujita Y., Miyaoka T., Ezoe S., Horiguchi J. Importance of measures to prevent suicides related to the Great East Japan Earthquake among women // Psychiatry and Clinical Neurosciences. 2015; 69(9): pp.596.
31. Inoue K., Fujita Y., Miyaoka T., Yano S., Morita E., Ishibashi Y., et al. Pilot study aiming at early detection of anxiety and stress in medical staff. The 112th Annual Meeting of the Japanese Society of Psychiatry and Neurology. 4 June, 2016: General Presentation (in Japanese).
32. Inoue K., Tanii H., Okazaki Y., Fujita Y., Sakuta A.,
Ono Y. The Present Situation of Rework Programs in Japan for Individuals on Long-Term Leaves of Absence due to Mental Disorders: A Review // International Medical Journal. 2008; 15(5): pp.333-336.
33. Inoue K., Hashioka S., Takeshita H., Kamura M., Fujita Y. Serum cortisol levels and life habit in rural junior high school students in Japan: under review.
34. Inoue K., Kaiya H., Hara N., Okazaki Y. A discussion of various aspects of panic disorder depending on presence or absence of agoraphobia // Comprehensive Psychiatry. 2016; 69: pp.132-135.
35. Inoue K., Kaiya H., Hara N., Okazaki Y. Comparison of clinical features of panic disorder patients with and without family history of psychiatric disorders // Science & Healthcare. 2017; 5: pp.67-75.
36. Inoue K., Tanii H., Kaiya H., Abe S., Fujita Y., Masaki M., et al. The Risk for Suicide in Japan: Review // International Medical Journal. 2007; 14(3): pp.203-206.
37. Kairkhanova Y., Saimova A., Uzbekov D., Chaizhunusova N, Fujimoto N. EFFECTS OF EXPOSURE TO RADIOACTIVE 56MnO2 POWDER ON HYALURONAN SYNTHASE 2 IN THE LUNGS OF RATS // Georgian Medical News. 2017; 270: pp.120-124.
38. Kondo Y., Tanabe T., Kobayashi-Miura M., Amano H., Yamaguchi N., Kamura M., et al. Association between feeling upon awakening and use of information technology devices in Japanese children // Journal of Epidemiology. 2012; 22(1): pp.12-20.
39. Kochi University. http://www.kochi-u.ac.jp/information/2018082100011 /. Last access: 16 June, 2019 (in Japanese).
40. Kimura-Kataoka K., Ueki M., Takeshita H., Fujihara J., Iida R., Kawai Y., et al. Identification of the functional alleles of the nonsynonymous single-nucleotide polymorphisms potentially implicated in systemic lupus erythematosus in the human deoxyribonuclease I gene // DNA and Cell Biology. 2014; 33(8): pp.492-502.
41. Kochi University. http://www.kochi-u.ac.jp/information/2018111200019/. Last access: 16 June, 2019 (in Japanese).
42. Kochi University. http://www.kochi-u.ac.jp/information/2019041000014/. Last access: 16 June, 2019 (in Japanese).
43. Limoa E., Hashioka S., Miyaoka T., Tsuchie K., Arauchi R., Azis I.A., et al. Electroconvulsive shock attenuated microgliosis and astrogliosis in the hippocampus and ameliorated schizophrenia-like behavior of Gunn rat // Journal of Neuroinflammation. 2016; 13(1): pp.230.
44. Limoa E., Hashioka S., Miyaoka T., Tsuchie K., Arauchi R., Azis I.A., et al. Electroconvulsive shock attenuated microgliosis and astrogliosis in the hippocampus and ameliorated schizophrenia-like behavior of Gunn rat // Journal of Neuroinflammation. 2016; 13(1): pp.230.
45. Tapbergenov S.O., Zhetpisbaev B.A., Ilderbayev O.Z., Zhetpisbaeva H.S., Olzhayeva R.R., Prozor I.I., et al. Free radical oxidation in rats in the delayed period after combined exposure to dust and radiation // Bulletin of Experimental Biology and Medicine. 2013; 154(6): pp.747749.
46. Pak L., Noso Y., Chaizhunusova N., Anambaeva Z., Adylkhanov T., Takeichi N., et al. Disorder of Endothelia Vessels' Functional State with Malignant Tumors in Patients
tëd !SJVl U Medical education
nir- SEMBY MEDICAL UNIVERSITY
Exposed Anthropogenic Radiation // Asian Pacific Journal of Cancer Prevention. 2016; 17(2): pp.575-579.
47. Zhumagaliyeva A., Ottaviani S., Greulich T., Gorrini M., Vogelmeier C., Karazhanova L., et al. Case-finding for alphal-antitrypsin deficiency in Kazakh patients with COPD // Multidisciplinary Respiratory Medicine. 2017; 12: pp.23.
48. Markabayeva A., Bauer S., Pivina L., Bj0rklund G., Chirumbolo S., Kerimkulova A., et al. Increased prevalence of essential hypertension in areas previously exposed to fallout due to nuclear weapons testing at the Semipalatinsk Test Site, Kazakhstan // Environmental Research. 2018; 167: pp.129-135.
49. Moriwaki S., Kanda H., Kakamu T., Kobayashi-Miura M., Inoue K. Factors Associated with Short-Term Institutionalized Nursing Care among First-Time Users of Home-Visit Nursing Stations in Rural Japan // International Medical Journal. 2017; 24(3): pp.256-259.
50. Miyaoka T., Ieda M., Hashioka S., Wake R., Furuya M., Liaury K., et al. Analysis of oxidative stress expressed by urinary level of biopyrrins and 8-hydroxydeoxyguanosine in patients with chronic schizophrenia // Psychiatry and Clinical Neurosciences. 2015; 69(11): pp.693-698.
51. Prilutskaya M., Bersani F.S., Corazza O., Molchanov S. Impact of synthetic cannabinoids on the duration of opioid-related withdrawal and craving among patients of addiction clinics in Kazakhstan: A prospective case-control study // Human Psychopharmacology. 2017; 32(3): pp.e2618.
52. Shichijo K., Fujimoto N., Uzbekov D., Kairkhanova Y., Saimova A., Chaizhunusova N., et al. Internal exposure to neutron-activated 56Mn dioxide powder in Wistar ratsPart 2: pathological effects // Radiation and Environmental Biophysics. 2017; 56(1): pp.55-61. Erratum in: Radiation and Environmental Biophysics. 2017; 56(2): pp.203-204.
53. Tsutani Y., Ohara M., Suzuki T., Minami K., Miyahara E., Kameda A., et al. Docetaxel and S-1 as a firstline treatment in patients with advanced or recurrent gastric cancer // Anticancer Research. 2009; 29(7): pp.2775-2779.
54. Takeshita H., Yasuda T., Nakajima T., Mogi K., Kaneko Y., Iida R., et al. A single amino acid substitution of Leu130Ile in snake DNases I contributes to the acquisition of thermal stability // European Journal of Biochemistry. 2003; 270(2): pp.307-314.
55. Takeshita H., Nakajima T., Mogi K., Kaneko Y., Yasuda T., Iida R., et al. Rapid quantification of DNase I activity in one-microliter serum samples // Clinical Chemistry. 2004; 50(2): pp.446-448.
56. Takeichi N., Hoshi M., Iida S., Tanaka K., Harada Y., Zhumadilov Z., et al. Nuclear abnormalities in aspirated thyroid cells and chromosome aberrations in lymphocytes of residents near the Semipalatinsk nuclear test site // Journal of Radiation Research. 2006; 47 Suppl A: pp.A171-177.
57. The Yomiuri Shimbun (Kochi). 19 August, 2018: 28 (in Japanese).
58. The Kochi Shimbun (Yuukan). 22 August, 2018: 6 (in Japanese).
59. The Asahi Shimbun (Kochi). 2 February, 2019: 31 (in Japanese).
60. Ueki M., Kimura-Kataoka K., Takeshita H., Fujihara J., Iida R., Sano R., et al. Evaluation of all non-synonymous single nucleotide polymorphisms (SNPs) in the genes encoding human deoxyribonuclease I and I-like 3 as a functional SNP potentially implicated in autoimmunity // The FEBS Journal. 2014; 281(1): pp.376-390.
61. Ueki M., Kimura-Kataoka K., Fujihara J., Takeshita H., Iida R., Yasuda T. Evaluation of all nonsynonymous single-nucleotide polymorphisms in the gene encoding human deoxyribonuclease I-like 1, possibly implicated in the blocking of endocytosis-mediated foreign gene transfer // DNA and Cell Biology. 2014; 33(2): pp.79-87.
62. Ueki M., Takeshita H., Utsunomiya N., Chino T., Oyama N., Hasegawa M., et al. Survey of single-nucleotide polymorphisms in the gene encoding human deoxyribonuclease I-like 2 producing loss of function potentially implicated in the pathogenesis of parakeratosis // PLoS One. 2017; 12(4): pp.e0175083.
63. Ueki M., Fujihara J., Kimura-Kataoka K., Yamada K., Takinami Y., Takeshita H., et al. Low genetic heterogeneity of copy number variations (CNVs) in the genes encoding the human deoxyribonucleases 1 -like 3 and II potentially relevant to autoimmunity // PLoS One. 2019; 14(4): pp.e0215479.
64. Nishimura Y., Tanii H., Fukuda M., Kajiki N., Inoue K., Kaiya H., et al. Frontal dysfunction during a cognitive task in drug-naive patients with panic disorder as investigated by multi-channel near-infrared spectroscopy imaging // Neuroscience Research. 2007; 59(1): pp.107112.
65. Yokoyama C., Kaiya H., Kumano H., Kinou M., Umekage T., Yasuda S., et al. Dysfunction of ventrolateral prefrontal cortex underlying social anxiety disorder: A multichannel NIRS study // NeuroImage Clinical. 2015; 8: pp.455-461.
Контактная информация:
Чайжунусова Найля Жакияновна - д.м.н. НАО «Медицинский университет Семей». г.Семей, Республика Казахстан. Почтовый адрес: Республика Казахстан, 071400, Восточно-Казахстанская область, г. Семей, ул. Абая Кунанбаева 103;
E-mail: [email protected] Телефон: 87771450100
