Научная статья на тему 'Variability of body content parameters as an indicator of biological age in humans: intraand inter-group aspects'

Variability of body content parameters as an indicator of biological age in humans: intraand inter-group aspects Текст научной статьи по специальности «Фундаментальная медицина»

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Ключевые слова
STATURE / BODY COMPOSITION / BIOLOGICAL AGE / AGEING RATES / LONG-LIVERS

Аннотация научной статьи по фундаментальной медицине, автор научной работы — Lapshina Natalia, Negasheva Marina

Biological age assessment is a commonly used method for investigation of ageing processes in contemporary populations. In our study, we have used the method suggested by Gorelkin A.G. and Pinkhasov B.B. (2008) based on parameters of the stature, with the help of which, using the multiple regression equation, individual determination of the biological age and ageing rates in men and women can be performed. Anthropometric examination (total body sizes and body mass components) of 423 people (239 men and 184 women) at the age from 52 to 104 years old has been carried out in the three cities (Moscow, Barnaul, Tiraspol) with different ecological and socioeconomic conditions. Moscow is a megalopolis with population density maximal for Russia (more than 11.5 mln people). Barnaul is an administrative and scientific (research, medical, educational) center of Altai Region, one of the largest Siberian cities (633,000 people). Tiraspol is a capital of Trans-Dniester Moldavian Republic (in the south-east of Europe) with the population about 156,000 people. When biological age parameters (BA) were compared with the calendar age (CA), groups with slowed (BA < CA 7 years), medium (BA = CA ± 7) and accelerated (BA > CA + 7) ageing rates have been detected in the examined subjects. In women and men with the slowed ageing rates, lower values of body mass index (BMI), decreased amount of total body mass and higher level of specific metabolism (kcal/m²) have been seen. Fat accumulation in the area of hips is more characteristic for women (based on the ratio of waist/hips circumferences), and for men on the trunk. All long-livers (36 women) appeared in the group with slowed ageing rates in accordance with their stature and based on biological age. In the group with accelerated ageing rates, disharmonic variants of fat topography have been observed: for women android, for men gynoid. Regional differences in the distribution of prevalence of different versions of ageing rates have been revealed: in Moscow, a slowed variant of development of involution age-specific changes is the most common (both in men and women).

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Текст научной работы на тему «Variability of body content parameters as an indicator of biological age in humans: intraand inter-group aspects»

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Section AGEING and SENESCENCE

VARIABILITY OF BODY CONTENT PARAMETERS AS AN INDICATOR OF BIOLOGICAL AGE IN HUMANS: INTRA- AND INTER-GROUP ASPECTS

Lapshina Natalia, Negasheva Marina

Department of Anthropology, Biological Faculty, LLomonosov Moscow State University, Moscow, Russia

Biological age assessment is a commonly used method for investigation of ageing processes in contemporary populations. In our study, we have used the method suggested by Gorelkin A.G. and Pinkhasov B.B. (2008) based on parameters of the stature, with the help of which, using the multiple regression equation, individual determination of the biological age and ageing rates in men and women can be performed. Anthropometric examination (total body sizes and body mass components) of 423 people (239 men and 184 women) at the age from 52 to 104 years old has been carried out in the three cities (Moscow, Barnaul, Tiraspol) with different ecological and socioeconomic conditions. Moscow is a megalopolis with population density maximal for Russia (more than 11.5 mln people). Barnaul is an administrative and scientific (research, medical, educational) center of Altai Region, one of the largest Siberian cities (633,000 people). Tiraspol is a capital of Trans-Dniester Moldavian Republic (in the south-east of Europe) with the population about 156,000 people. When biological age parameters (BA) were compared with the calendar age (CA), groups with slowed (BA < CA - 7 years), medium (BA = CA ± 7) and accelerated (BA > CA + 7) ageing rates have been detected in the examined subjects. In women and men with the slowed ageing rates, lower values of body mass index (BMI), decreased amount of total body mass and higher level of specific metabolism (kcal/m2) have been seen. Fat accumulation in the area of hips is more characteristic for women (based on the ratio of waist/hips circumferences), and for men - on the trunk. All long-livers (36 women) appeared in the group with slowed ageing rates in accordance with their stature and based on biological age. In the group with accelerated ageing rates, disharmonic variants of fat topography have been observed: for women - android, for men - gynoid. Regional differences in the distribution of prevalence of different versions of ageing rates have been revealed: in Moscow, a slowed variant of development of involution age-specific changes is the most common (both in men and women). The study has been performed at financial support of the Russian Foundation for Basic Research, grant #12-06-00265.

Key words: stature, body composition, biological age, ageing rates, long-livers

Contact information: Lapshina Natalia, e-mail: [email protected].

ALLOSTATIC LOAD AND FRAILTY MEASURES AMONG POLISH URBAN AND RURAL 55+ SUBJECTS

Nowaczyk Paulina Malgorzata1, Wozniewicz Malgorzata1, Jeszka Jan1, Crews Douglas E.2, Sone Yoshiaki3

1Department of Human Nutrition and Hygiene, Po%nan University of Life Sciences, Po%nan, Poland 2Department of Anthropology, The Ohio State University, Columbus, USA 3Graduate School of Human Life Science, Osaka City University, Osaka, Japan

During life span human body is exposed to numerous stressors, which force changes in internal environment, in order to adapt to present conditions. Allostatic load concept was created to measure the cumulative effect of those stressors on the body. The aim of the study was to compare allostatic load (AL) and indicators of frailty between urban and rural elderly from Greater Poland province. In all 216 female and male individuals aged >55 years were enrolled into the study. To determine AL following variables were measured: WHR, diastolic and systolic blood pressure, ratio of total to LDL cholesterol, HDL cholesterol, glycated hemoglobin, serum dihydroepiandosterone-sulfate, overnight urinary cortisol, adrenaline and noradrenaline. Measures

Vestnik Moskovskogo Universiteta. Series 23 ANTHROPOLOGIYA — 3/2014

19th Congress of the European Anthropological Association Lomonosov MSU, Moscow, Russia, 25th - 29th August, 2014

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