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Features of course of idiopathic trigeminal neuralgia between genders
11. Vigen R, O'Donnell C, Barón AE, Ho PM, et al. Association of Testosterone Therapy With Mortality, Myocardial Infarction, and Stroke in Men With Low Testosterone Levels. JAMA.2013;310 (17): 1829-1836.
DOI: http://dx.doi.org/10.20534/ESR-16-9.10-83-85
Juraeva Dilsora Nuriddinovna, Scientist-researcher, State Medical Institute Abu Ali Ibn Sina, Department of Neuralgia, Ministry of Health of the Republic of Uzbekistan Bukhara E-mail: [email protected]
Features of course of idiopathic trigeminal neuralgia between genders
Abstract: To learn etiology geneticist fact concerned with sex of neuralgia of trigeminal nerve. As a conclusion, we can say that idiopathic neuralgia is the most spreaded type of trigeminal neuralgia. Men have more cases of catching this illness than women. At men this disease will occur as losing of taste. Disease-producing factors of neuralgia at men: shaving, tooth brushing, draught; at women: tooth brushing, laughter, draught. A neuralgia attack both at men and women often occurs during summer time. Dependence of duration of illness from gender is not defined.
Keywords: trigeminal neuralgia, Doppler, transcranial Dopplerography, cerebral hemodynamic.
Recently "idiopathic" origin of diseases is very well studied. The term "idiopathic" has been conditionally used for the first time in 1988 by International Headache Classification.
The first attack ofpain occurs without any reasons in 34% cases, during dental treatment in 27% cases, and its connected with senses in 17% cases, in other cases the onset of the illness occurs in combination to different factors (sudden cooling offace, respiratory infections, local wounds and others) [4; 6; 7]. Ethiopathogenesis of course of acute period of trigeminal neuralgia has been considered as uncertain matter until now. Because of problems on early diagnostics, patients often address and are directed to other specialists. In turn, it demands to study disease on the basis of modern technologies. Course of the illness, its non-treatability still creates some problems.
During the last years pathogenesis of special diseases of brain has been studied against functional systems of organism. It helps to define the pathological phenomena of mechanisms of former and new development [1; 3; 6; 7]. Taking into account progressive development of disease and applied physiotherapeutic reflex-therapeutic of resistance to treatment, patients with trigeminal neuralgia disease have surgical operations. Pathogenesis of diseases can be explained by several theories. In many cases, its reason is intra — and extracranial compressions. This can be occur because of space-occupying lesion (tumour) of cranial fossa (neurinoma of acoustical nerve, meningioma, glioma of pons), disposition and artery expansion of cerebellum, aneurysm of the basic artery, tunnel syndrome (at the expense of compression of 2nd and 3rd germinal unit, a crack of the channel of a bone and congenital narrowness of bottom jaw and addition of disease of vessels at old men) odontogenic or rhi-nogenous inflammations. Disease can develop: at removal of teeth, odontogenic neuralgia, as a result of infringement of blood circula-
tion in brain, as a result of herpes infection, it becomes rare the reason demyelinization of trigeminal nerve covers at spreaded sclerosis [2; 5; 6].
The term "idiopathic" has been conditionally used for the first time in 1988 by International Headache Classification. There tunnel compression mechanism this form of neuralgia was analyzed.
From the point of view of spread, among diseases of nerves of brain6 trigeminal neuralgia takes second place after face nerve neuropathy [3; 4]. Trigeminal neuralgia is often observed at middle and old man, but to 40-year-old age the first attacks make 30-35%, at 70 and more year old the first painful attack makes 2-3 percent. Women are ill than men (Shedrenko V. V. 2005) is more often.
Obj ective: To learn etiology geneticist fact concerned with sex of neuralgia of trigeminal nerve
Materials and methods
We have examined 268 patient, age from 30 to 70 (171 of them women (63,8%), 97 men (36,2%)) who were treated on neurology and maxillofacial surgery of medical center of Bukhara region. Results were determined with method of questioning.
Results and discussion
According to our examination the reason of illness most ofpa-tients is unknown as idiopathic neuralgia is atop, and observed for men much more than for women (53, 6:41, 5). At the same time trigeminal neuralgia arose after wounds, 4, (4,1%) for men and 10 (5,8%) for women. Trigeminal neuralgia observed for women like a consequences of herpes (1,8%), diabetes mellitus (1,8%), acute infection (3,5%) when for men this kind of situation were not discovered.
The main etiological facts of concerning neuralgia of trigeminal nerve with sex are given on table 1.
Table 1. - The main etiological facts of concerning neuralgia of trigeminal nerve with sex
No. EXCITING CAUSE Men Women
Number Abc % Number Abc %
1 2 3 4 5 6
1 Idiopathic 52 53,6±5,1 71 41,5±3,8***
2 After Sores 4 4,1±2,0 10 5,8±1,8
3 Acute Infection - - 6 3,5±1,4
4 Herpes - - 3 1,8±1,0
Sectiom 6. Medical science
1 2 3 4 5 6
5 SARS 9 9,3±2,9 18 10,5±2,3
6 After Dental Treatment 6 6,2±2,4 15 8,8±2,2
7 Diabetes Mellitus 1 1±1,0 3 1,8±1,0
Note: *** Reliabilities of difference between men's and women's groups is p<0.05
Analysis of facts which rouse attack of neuralgia of trigeminal Laughing—men 25,8%, women 38,6%. Shaving—men 46,4%. Make nerve. Taking bath — men 28,9%, women 22,2%. Brushing teeth — up — women 15,2%. Draught — men 55,7%, women 53,8% Facts men 39,2%, women 38,0%. Facer — men 18,6%, women 21,6%. which rouse attack of neuralgia oftrigeminal nerve given on Table 2
Table 2. - Facts which rouse attack of neuralgia of trigeminal nerve
Facts which rouse attack of neuralgia of trigeminal nerve. Men Women
Number Abc % Number Abc %
Taking bath 28 28,9±4,6 38 22,2±3,2
Shaving 45 46,4±5,1 - -
Brushing teeth 38 39,2±5,0 65 38,0±3,7
Facer 18 18,6±3,9 37 21,6±3,1
Make up - - 26 15,2±2,7
Laughing 25 25,8±4,4 66 38,6±3,7
Draught 54 55,7±5,0 92 53,8±3,8
Examining changes of sense showed that both for men and for difference between gender, what is given in table 3. women hyperesthesia observed more than anesthesia. There was no
Table 3. - Changing of sense on neuralgia of trigeminal nerve
Changing of sense Men Women
Number Abc % Number Abc %
Hyperesthesia 71 73,2±4,5 115 67,3±3,6
Hypaesthesia 21 21,6±4,2 44 25,7±3,3
Anesthesia 4 4,1±2,0 10 5,8±1,8
Examining taste men and women who have neuralgia of trigem- (20,6%: 8,8%), what is given in table 4. inal nerve showed that men's taste districted more than women's
Table 4. - Disturbing taste
Changing of taste Men Women
Number Abc % Number Abc %
1. No change 77 79, 4±4,1 156 91,2±2,2**
2. Change 20 20,6±4,1 15 8,8±2,2**
A. on the Right 10 10,3±3,1 9 5,3±1,7
B. on the Left 10 10,3±3,1 6 3,5±1,4
Note: *** Reliabilities of difference between men's and women's groups is p<0.01
Results of analyzing attack of neuralgia of trigeminal nerve Analyses shows that in summer both men and women have
according to season: In winter — men 29,9%, women 21,6%. In more attack of neuralgia of trigeminal nerve as in summer people use spring — men 18,6%, women 22,8%. In summer — men 39,2%, air-conditioner what has a bad influence on neuralgia of trigeminal women 38,6%. In autumn — men 12,4%, women 17%. nerve. Results of analyzing attack of neuralgia of trigeminal nerve
according to season given in table 5.
Table 5. - Results of analyzing attack of neuralgia of trigeminal nerve according to season
No. Gender All Season
Winter Spring Summer Autumn
Number Abc % Number Abc % Number Abc % Number Abc %
1. Women 171 37 21,6±3,1 39 22,8±3,2 66 38,6±3,7 29 17,0±2,9
2. Men 97 29 29,9±4,6 18 18,6±3,9 38 39,2±5,0 12 12,4±3,3
Analyses of idiopathy and chronic illness of patients for men — for men and women (58,8: 55,0). Idiopathy and chronic form of ill-14,4%, for women — 14,6%. Illness for a year for men — 16,5%, for ness similar for both men and women. Continuous of illness given in women — 17,5%. Results of illness during several years are similar table 6.
Clinical and biochemical justification of prevention of basal seat tissues atrophy in the maxilla
Table 6. - Continuous of illness
No Antecedent anamnesis Men Women
Number Abc % Number Abc %
1 1-15 days 14 14,4±3,6 25 14,6±2,7
2 1-3 month 10 10,3±3,1 21 12,3±2,5
3 1 year 16 16,5±3,8 30 17,5±2,9
4 Several years. 57 58,8±5,0 94 55,0±3,8
Analyses of the number of attacks of neuralgia of trigeminal for men and women. what given in the table 7. nerve during a day showed that it achieves more than 10 times both
Table 7. - Number of attacks of neuralgia of trigeminal nerve during a day
No Times of attack for a day Men Women
Number Abc % Number Abc %
1 1-2 times 10 10,3±3,1 17 9,9±2,3
2 4-5 times 30 30,9±4,7 56 32,7±3,6
3 10 times 39 40,2±5,0 64 37,4±3,7
4 10 more than times 18 18,6±3,9 35 20,5±3,1
As a conclusion, we can say that idiopathic neuralgia is the most spreaded type of trigeminal neuralgia. Men have more cases of catching this illness than women. At men this disease will occur as losing of taste. Disease-producing factors of neuralgia at men:
shaving, toothbrushing, draught; at women: toothbrushing, laughter, draught. A neuralgia attack both at men and women often occurs during summer time. Dependence of duration of illness from gender is not defined.
References:
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4. Melnikova O. N. "Neuralgia of Trigeminal Nerve"//Mag. "Head |Ache", - № 7, - 2004.
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DOI: http://dx.doi.org/10.20534/ESR-16-9.10-85-87
Ziyadullaeva Nigora Saidullaevna, PhD Tashkent state dental Institute, Uzbekistan, Department of faculty prosthetic dentistry E-mail: [email protected]
Clinical and biochemical justification of prevention of basal seat tissues atrophy in the maxilla
Abstract: Complete removable dentures have a negative effect on the tissues of basal seat resulting in atrophy of edentulous jaws. It needs correction of the microcirculation of basal seat tissues.
Keywords: removable dentures, complete dentures, edentulous ridge/jaw, basal seat, oral mucose membrane, negative effect of removable dentures.
Most of all, a removable denture is inevitable need for replacing both the complete edentulous arch and the partial teeth loss. Despite achievements in manufacturing techniques ofthe complete removable dentures, a question ofimprovement oftheir stability need its decision.
Among all manufactured dentures the removable complete dentures are the most non-physiological. Removable dentures and the materials, which from they have made, can have a negative effect on the oral mucous membrane, which condition is balanced.
Stability of the complete removable dentures depends on a condition of buffer zones of a basal seat, which, in turn, closely depend on microcirculation of the last one.
There is compression syndrome during complete removable dentures is used, resulting in endothelial damage of blood vessels, which disrupts capillary permeability, decreases the tone of blood vessels, slows blood flow, deposits fibrin on the vascular wall, stimulates collagen activity, increases aggregation and adhesion of
