Fabrication of samarium nanoparticles by femtosecond laser ablation in liquid Текст научной статьи по специальности «Нанотехнологии»

LM-PS-13

Fabrication of samarium nanoparticles by femtosecond laser ablation in liquid

E. Popova-Kuznetsova1, A. Popov1, G. Tikhonovsky1, S. Klimentov1, V. Duflot2, I. Zavestovskaya1, A. Kabashin1,3

1MEPhI- Institute of Engineering Physics for Biomedicine PhysBio, Bio-nanophotonics Laboratory, Moscow, Russian Federation

2Scientific-Research Physical Chemistry Institute, Branch of the L. Ya Karpov, Obninsk, Russian Federation

3Aix Marseille University- CNRS, LP3 laboratory, Marseille, France

Nuclear nanomedicine provides unique opportunities to treat tumors due to its targeting ability, good loading capacity and enhanced retention. This field of science has become increasingly important over the last decades, promising an attractive and powerful alternative to conventional chemotherapy. However, synthesis of radioactive agents in nanoscale is rather challenging. Here, we have chosen a different way. First, we produce nanomaterials and only after that "activate" them into radioactive form. Our approach is based on synthesis of enriched Sm-152 oxide nanoparticles by femtosecond laser ablation in liquids. We have shown that it is possible to produce 100 nm nanoparticles with different shape fractions. Moreover, application of additional laser fragmentation step allows one to finely tune nanoparticles size between 5 and 20 nm.