Coronavirus Infections of Animals and Humans: Ideological Use in Media vs Evidence-Based Scientific Approach Текст научной статьи по специальности «Ветеринарные науки»

Coronavirus Infections of Animals and Humans: Ideological Use in Media vs Evidence-Based Scientific Approach

Rev Fr Anton P. Gerilovych1, Borys T. Stegniy, Oleksandr M. Kornieikov, Denys V. Muzyka, Iryna O. Gerilovych, Vitaliy I. Bolotin, Larysa V. Kovalenko, Vasiliy L. Are-fiev, Oksana B. Zlenko, and Olena V. Kolchyk

Anton P. Gerilovych,

Fr priest, PhD, ScDr (Veterinary), Professor (Veterinary Virology),

Corresponding Member of the National Academy of Agrarian Sciences of Ukraine,

Deputy Director for Scientific Research,

Institute for Experimental and Clinical Veterinary Medicine,

Ukraine

Borys T. Stegniy,

ScDr (Veterinary), Professor, NAAS Academician,

Director of Institute for Experimental and Clinical Veterinary Medicine,

Head of Laboratory for Avian Viral Diseases,

Ukraine

Oleksandr M. Kornieikov,

PhD (Veterinary), DVM, Head of Laboratory for Virology,

Institute for Experimental and Clinical Veterinary Medicine, Ukraine

Denys V. Muzyka,

ScDr (Veterinary), Senior Researcher,

Head of Department for Avian Diseases,

Institute for Experimental and Clinical Veterinary Medicine,

Ukraine

1 Please send the correspondence to e-mail: antger2011@gmail.com.

020130318-1

Iryna O. Gerilovych,

PhD (Veterinary), DVM,

Head of Laboratory for Biosafety and Control,

Institute for Experimental and Clinical Veterinary Medicine,

Ukraine

Vitaliy I. Bolotin,

PhD (Veterinary), DVM,

Head of the Animal Brucellosis Laboratory,

Institute for Experimental and Clinical Veterinary Medicine,

Ukraine

Larysa V. Kovalenko,

PhD (Biology), DVM,

Head of Laboratory for Biochemistry,

Institute for Experimental and Clinical Veterinary Medicine,

Ukraine

Vasiliy L. Arefiev,

PhD (Veterinary), DVM,

Head of Laboratory for Microbial Genetics,

Institute for Experimental and Clinical Veterinary Medicine,

Ukraine

Oksana B. Zlenko,

Junior Researcher,

Laboratory for Microbial Genetics,

Institute for Experimental and Clinical Veterinary Medicine, Ukraine

Olena V. Kolchyk,

PhD (Veterinary), DVM, Senior Researcher,

Leading Researcher of Laboratory for Porcine Diseases, Institute for Experimental and Clinical Veterinary Medicine, Ukraine

Article No / Номеръ статьи: 020130318

For citation (Chicago style) / Для цитировашя (стиль «Чикаго»):

Gerilovych, Anton P., Rev., Stegniy, Borys T., Kornieikov, Oleksandr M., et al. 2020. "Coronavirus Infections of Animals and Humans: Ideological Use in Media vs Evidence-Based Scientific Approach." Beacon J Stud Ideol Ment Dimens 3, 020130318.

Versions in different languages available online: Chinese only (traditional).

Permanent URL links to the article:

HANDLE: 20.500.12656/thebeacon.3.020130318

http://thebeacon.ru/pdf/Vol.%203.%20Issue%202.%20020130318%20CHI-T.pdf

Received in the original form: 16 August 2020 Review cycles: 2

1st review cycle ready: 22 September 2020 Review outcome: 3 of 3 positive Decision: To publish with major revisions 2nd review cycle ready: 25 October 2020 Accepted: 27 October 2020 Published online: 29 October 2020

ABSTRACT

Gerilovych, Anton P., 5tegniy, Borys T., Kornieikov, Oleksandr M., Muzyka, Denys V., Gerilovych, Iryna O., Bo-lotin, Vitaliy I., Kovalenko, Larysa V., Arefiev, Vasiliy L., Zlenko, Oksana B., and Olena V. Kolchyk. Coronavirus Infections of Animals and Humans: Ideological Use in Media vs Evidence-Based Scientific Approach. The novel coronavirus 5AR5-CoV-2 that causes COVD-19 disease, was mainly described as a something extraordinary in media discourse. Its "unusual," almost "mystical" properties have been constantly invented by world media sources since January 2020 thus far. Critical comparison of the real epidemiological, physical, chemical and biological properties of 5AR5-CoV-2 with most common causative agents of coronavirus family demonstrates that principles and techniques of laboratory diagnostics and prophylaxis of 5AR5-CoV-2 should be built only on the basis of evidence-based medicine, not on imaginary properties of the virus that were created with ideological purposes.

Key words: 5AR5-CoV-2, COVD-19, media ideology, ideology in science, evidence-based medicine, ideological control

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РЕЗЮМЕ

Герпловпчъ А.П., Стегнт Б. Т., Корнейковъ О. М., Музыка Д. В., Герпловпчъ И. О., Болотпнъ В. И., Коваленко Л. В., Арефьевъ В. Л., Зленко О. В., Колчпкъ О. В.

Коронавирусныя инфекци животныхъ и людей: Медийное идеологическое использоване противъ подхода, основан-наго на доказательныхъ принципахъ. Новый коронавирусъ 5AR5-CoV-2, вызывающа заболЪваые COVID-19, въ основ-номъ описывался меда-источниками какъ н-Ьчто экстраординарное. Его «необычныя», почти «мистичесмя» свойства постоянно придумываются мiровыми СМИ начиная съ января 2020 года. Критическое сравнеНе реальныхъ эпидемюлоги-ческихъ, физическихъ, химическихъ и бюлогическихъ свойствъ 5AR5-CoV-2 съ наиболее распространенными возбудителями семейства коронавирусовъ показываетъ, что принципы и методы лабораторной Дагностики и профилактики 5AR5-CoV-2 сл-Ьдуетъ строить только на основами доказательной медицины, а не на воображаемыхъ свойствахъ вируса, созданныхъ съ идеологическими целями.

Ключевыя слова: 5AR5-CoV-2, COVID-19, медтоыя идеологiи, идеологiя въ наук-Ь, доказательная медицина, идео-логическiй контроль

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Funding. This work did not receive any specific financing from any governmental, public, commercial, non-profit, community-based organisations or any other source.

Conflicts of interest. None declared.

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EXTENDED SUMMARY

Gerilovych, anton P., Rev, Stegniy, Borys T., Kornieikov, Oleksandr M., Muzyka, Denys v., Gerilovych, Iryna O., Bolotin, Vitaliy I., Kovalenko, Larysa V., Arefiev, Vasiliy L., Zlenko, Oksana B., and Olena V. Kolchyk. Coronavirus Infections of Animals and Humans: Ideological Use in Media vs Evidence-Based Scientific Approach.

Coronaviruses represent a significant number of species, variable and genetically plastic (in terms of mutations and recombination) group of RNA-containing viruses. The instability of the viral genome, and, as a consequence, the divergence of the antigenic structure of these pathogens explain the necessity of evidence-based in-depth studies of the ecology and biological properties of coronaviruses, including the novel pathogen SARS-CoV-2. Despite the lack of potential anthropopathogenicity in animal coronaviruses, they can serve as an effective model for testing the effectiveness of disinfectants, antiviral therapies and vaccines designed to control and contain the SARS-CoV-2 infection. Sober comparing ecological and biological properties of animal and human coronaviruses may lead to a conclusion that a promising area for the development of specific prevention of SARS-CoV-2 spread is the development of candidate drugs based on recombinant surface and internal antigens of the pathogen. Therefore, SARS-CoV-2 cannot be regarded as an unprecedented viral threat to humanity whose properties cannot be but a mystery to science and society.

This deduction can be never heard in TV news on prime world TV channels, often government-sponsored. The SARS-CoV-2-related "news"-like stories for general population are ideologically prepared, checked and double-checked. They contain several permanent narratives about the novel virus with key phrases aimed at influencing people's fears and raising their anxiety. Some of key phrases are "second wave," "excessive mortality," "Wuhan," "heaps of coffins," "protective costumes," "masks and gloves," "lockdowns." SARS-CoV-2 is ideologically depicted as the worst "plague" causing enormous number of victims. Moreover, ideologically the novel virus is described as "unknown," "mysterious," "unseen heretofore." Such phrases are common for TV news, talk shows, Internet communication. But even more importantly, they also penetrate academic discourse. The virus may be more or less dangerous, and all statements like this need be proven by medical evidence and statistical approach. One may observe that considerable amount of scientific publications in academic journals become ideologically tinted without necessary evidence. Media ideology of permanent fear before SARS-CoV-2 is universal for all parts of the world. However, it must not influence scientific study of the virus.

As an attempt of unprejudiced and ideology-free use of coronavirus-related information in the SARS-CoV-2 matter, we initiated pilot studies to clone in silico genes of two viral proteins S (spike) and N (nucleocapsid) into expressing plasmid vectors for subsequent transformation of bacterial and yeast cells to obtain recombinant antigens. GeneBank was used to find complete sequences of genes encoding the target proteins of the Wuhan-19 strain. Primer systems have been developed for the development and cloning of target fragments of the viral genome, as well as internal primers for screening recombinant clones. In the future, on the basis of these data, candidate drugs for immunisation against SARS-CoV-2 will be constructed and tested on laboratory animals.

The main task of the scientific approach, i.e. approach based on regarding the novel coronavirus pathogen in an unbiased and ideology-free way, may be approached starting with the comparison of all information on other animal and human coronaviruses that scientific community, veterinaries and clinicians possess so far, with the new data on SARS-CoV-2 that are received constantly since the beginning of 2020. Media ideology of SARS-CoV-2-related fear causes much threat to impartial and neutral studies and should be avoided in medical practice and scientific research.

/ Authors

Reverend Father Anton Pavlovich Gerilovych, PhD, Dr habil (Veterinary), Professor, is an Ukrainian Orthodox priest, the Deputy Director for Scientific Research of Institute for Experimental and Clinical Veterinary Medicine, Head of the Department of Molecular Epizootology, and Corresponding Member of the National Academy of Agrarian Sciences of Ukraine. Professor Fr Antony is the author and co-author of eleven diagnosticums, fifteen methodical recommendations, seventeen patents of Ukraine, more than one hundred articles on molecular diagnostics, epizootology and biotechnology, one mono-graph and scientific-methodical manual. Fr Gerilovych is the youngest corresponding members in Ukraine. As well he is one of the most influential Ukrainian theologians.

Borys T. Stegniy is ScDr (vet.), Professor, NAAS Academician, head of laboratory for avian viral diseases and director in the National Scientific Centre Institute for Experimental and Clinical Veterinary Medicine (Kharkiv, Ukraine). National project lead for scientific support of veterinary medicine. He has 45 years' experience in veterinary virology, microbiology, immunology, and biosafety. Co-author of multiple vaccines and diagnostics kits against Avian influenza, Newcastle disease, Chicken infectious bronchitis etc. Author and co-author of 30 books, over 700

papers dedicated to animal infectious diseases.

Oleksandr M. Kornieikov is PhD (vet.), DVM, head of laboratory for virology in the National Scientific Centre Institute for Experimental and Clinical Veterinary Medicine (Kharkiv, Ukraine). His scientific interests are concentrated in veterinary virology, immunology, and epidemiology areas. Co-author of vaccines against viral pneumoenterites of cattle, including IBR, BVD, and rota-coronaviral infections. Author and co-author of ~70 papers dedicated to cattle viral diseases.

Denys V. Muzyka is ScDr (vet.), Senior researcher, head of Department for avian diseases in the National Scientific Centre Institute for Experimental and Clinical Veterinary Medicine (Kharkiv, Ukraine). He has 20 years' experience in veterinary virology, and epidemiology. Co-author of multiple vaccines and diagnostics kits against Avian influenza, Newcastle disease, Chicken infectious bronchitis etc. Author and co-author of 4 books, over 200 papers dedicated to avian infectious diseases.

Iryna O. Gerilovych is PhD (vet.), DVM, head of laboratory for biosafety and control in the National Scientific Centre Institute for Experimental and Clinical Veterinary Medicine (Kharkiv, Ukraine). Areas of expertize are veterinary toxicology, food safety and biosafety. Author and co-author of 22 papers dedicated to food safety, 4 patents and 4 guidelines for toxicants detection.

Vitaliy I. Bolotin is PhD (vet.), DVM, Head of the Head of the Animal Brucellosis Laboratory of National Scientific Centre Institute for Experimental and Clinical Veterinary Medicine (Kharkiv, Ukraine). Major Research Interests: development and validation of new diagnostic

tools; study of immunogenic proteins of microorganisms and recombinant vaccine development; molecular epidemiology; study of genetic variability of viruses; bacteria antibiotic resistance study. 10 peer-reviewed publications.

Larysa V. Kovalenko is PhD (bio.), DVM, head of laboratory for biochemistry in the National Scientific Centre Institute for Experimental and Clinical Veterinary Medicine (Kharkiv, Ukraine). Her scientific interests are concentrated in veterinary virology, immunology, and clinical biochemistry. Author and co-author of 112 papers dedicated to animal diseases, 22 patents and 4 monographs.

Vasiliy L. Arefiev is PhD (vet.), DVM, head of laboratory for Microbial Genetics in the National Scientific Centre Institute for Experimental and Clinical Veterinary Medicine (Kharkiv, Ukraine). Areas of expertize are veterinary microbiology, and microbial genetics, and resistance of microorganisms. Author and co-author of 18 papers dedicated to molecular diagnostics of animal infectious diseases and one monograph.

Oksana B. Zlenko, Junior researcher of laboratory for Microbial Genetics in the National Scientific Centre Institute for Experimental and Clinical Veterinary Medicine (Kharkiv, Ukraine). Diagnostics of zoonotic diseases, recombinant biotechnologies, biosafety and biosecurity. Co-author of 7 articles and 3 utility patents.

Olena V. Kolchyk is PhD (vet.), Senior Researcher, DVM, leading researcher of laboratory for porcine diseases in the National Scientific Centre Institute for Experimental and Clinical Veterinary Medicine (Kharkiv, Ukraine). Areas of expertize are veterinary microbiology, virology and epidemiology. Author and co-author of vaccines technology from local microbial

strains' antigens, as well as convalescents sera, 55 papers and 18 patents dedicated to porcine infectious diseases.

Fr Anton P. Gerilovych, Borys T. Stegniy, Oleksandr M. Kornieikov, Denys V. Muzyka, Iryna O. Gerilovych, Vitaliy I. Bolotin, Larysa V. Kovalenko, Vasiliy L. Arefiev, Oksana B. Zlenko, Olena V. Kolchyk Institute for Experimental and Clinical Veterinary Medicine of the National Academy of Agrarian Sciences of Ukraine, 83 Pushkinskaya st, Kharkov 61023, Ukraine

© Rev Fr Anton P. Gerilovych; Borys T. Stegniy, Oleksandr M. Kornieikov, Denys V. Muzyka, Iryna O. Gerilovych, Vitaliy I. Bolotin, Larysa V. Kovalenko, Vasiliy L. Arefiev, Oksana B. Zlenko, and Olena V. Kolchyk Licensee The Beacon: Journal for Studying Ideologies and Mental Dimensions

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