Биотехнологии в медицине список научных статей
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Изменения в клетках-предшественницах стромального микроокружения костного мозга больных хроническим миелолейкозом в дебюте заболевания и в ходе лечения
Введение. У больных хроническим миелолейкозом (ХМЛ) изменены свойства клеток-предшественниц стромального микроокружения мультипотентные мезенхимальные стромальные клетки (ММСК) и колониеобразующие единицы фибробластов (КОЕф).Цель сравнительное изучение клеток-предшественниц стромального...
2019 / Петинати Н.А., Шипунова И.Н., Бигильдеев А.Е., Сац Н.В., Челышева Е.Ю., Шухов О.А., Петрова А.Н., Туркина А.Г., Дризе Н.И.WOSScopusВАКCASRSCIPubMed -
ВЫЖИВАЕМОСТЬ БАКТЕРИЙ ПРИ МОДЕЛИРОВАНИИ ОГРАЖДАЮЩИХ ПОВЕРХНОСТЕЙ СООРУЖЕНИЙ ДЛЯ СОЛЕТЕРАПИИ
Введение. Наземные сооружения для солетерапии, отличающиеся по составу минералов и модификации лечебных поверхностей, активно используются в России и за рубежом. Абиотические поверхности данных устройств подвержены микробному загрязнению, источниками которого являются верхние дыхательные пути,...
2019 / Кузнецова Марина Валентиновна, Маммаева М.Г., Баранников В.Г., Кириченко Л.В.ScopusВАКCASRSCIPubMed -
Tissue engineering of heart valves - challenges and opportunities
Background: Heart valve disease is a clinically serious condition. The replacement of damaged valves practiced since the 1950’s is the ultimate treatment for end-stage heart failure caused by severe valve dysfunction. The choice of adequate prosthesis is challenging. Unfortunately, the treatment...
2019 / Malcova Tatiana, Balutel Tatiana, Ciubotaru Anatol, Nacu Viorel -
Genetic predisposition to bronchopulmonary pathology
We studied 215 people who work in harmful industries, 90 of which had a history of bronchopulmonary pathology of occupational etiology and 125 of them without such pathology. The following polymorphisms of DNA repair genes were identified in real-time using polymerase chain reaction: XPD (rs13181,...
2019 / Andrushchenko T.A., Stroy D.O., Goncharov S.V., Dosenko V.E., Ishhejkin K.E. -
Restructuring of vessels of the thyroid gland after experimental thermal injury along with application of minced substrate of freeze-dried xenograft
Alterations in the vessels of the albino rats’ thyroid gland after experimental thermal injury in conditions of early necrectomy and the use of minced substrate of the freeze-dried xenograft have been studied. It has been established that the use of xenografts reduces the degree of destructive...
2019 / Korytskyi V.G., Nebesna Z.M., Kramar S.B. -
Features of remodeling cross-striated muscles of hind limbs in rats under conditions of experimental hypercholesterolemia
The study was performed with the purpose to study the features of cross-striated muscles remodeling of the femoral, knee and lower leg areas of the hind limbs in rats of pre-reproductive and reproductive age under conditions of experimental hypercholesterolemia. It was established that remodeling...
2019 / Yuryk І.І., Bodnar P. Ya., Bodnar Ya. Ya., Orel Yu. M. -
Histological changes in the duodenal wall in experimental pancreatitis
The morphological state of the duodenum in simulated cryogenic pancreatitis has been studied during the experiment on white rats. It has been established that on day 2 of the experiment the reactive changes occurred in the in the duodenal wall that were characterized by the dilatation of lumens and ...
2018 / Volkov K.S., Shuturma O. Ya., Nebesna Z.M., Getmaniuk І.B., Tupol L.D. -
Indicators cell cycle and DNA fragmentation in cells of small intestine mucosa 14, 21 and 30 days after skin burns on the background of pre-liminary infusion of solution lactoprotein with sorbitol or haes-lx 5%
In analyzing the data of cell cycle and DNA fragmentation of the cells of the mucous membranes of the small intestine of rats in the late stages after the thermal burn of skin 2-3 degrees, in the area of 21-23% of the body surface, on the background of the previous use of infusion solutions, it was ...
2018 / Gavryluk A.O., Galunko G.M., Chereshniuk I.L., Tikholaz V.O., Cherkasov E.V., Dzevulska І.V., Kovalchuk O.І. -
Bone stump formation in relation to the muscle tension value at amputation plastic surgery
Three series of experiments on 41 dogs with amputation in the medium third thigh and muscular plasty with muscle tension 916-962 μH (experimental group), 980-1100 μH and 650-800 μH (control groups). The monitoring lasted 1 and 3 months. In the 1st series of experiments with muscular tension 916-962 ...
2018 / Shevchuk V.I., Bezsmertnyi Yu. O., Bezsmertna H.V., Shevchuk S.V. -
Ultrastructural changes in pulmonary hemomicrocirculation at acute experimental pancreatitis
Experiment performed on 70 white male rats of the Vistar line by electron microscopic method, dynamics (12, 24, 48, 72 h) of ultrastructural changes of the hemomycocirculatory bed of lungs in experimental acute pancreatitis was studied. Established, that at 12 h after the beginning of the...
2018 / Zaiats L.M., Cherkasova V.V. -
The use of semi-thin section method in the study of stress-induced structural changes in lungs
The perfect knowledge of the microscopic structure of the appropriate organ is crucial in the solution of many urgent problems of clinical medicine. Better preservation of tissue structures is achieved when the tissues are embedded into epoxy resins followed up with the semi-thin section making. In ...
2018 / Koptev M.M., Vynnyk N.І., Kokovska O.V., Filenko B.M., Bilash S.M. -
Morphological state of the renal medulla in rats in case of an experimental burn injury under conditions of gekoton
The article presents structural changes of the renal medulla in experimental traumatic skin injury in rats under conditions of intravenous infusion of a colloid-hyperosmolar solution of gekoton. It was found that gekoton acts on the structure of the body as a cytoprotector. The cytoprotective...
2018 / Malikov O.V. -
Характеристика інфільтрації cd68+ та сd163+ макрофагами первинного вогнища та метастатичних уражень реґіонарних лімфовузлів при люмінальних інвазивних карциномах молочної залози в залежності від їх імунофенотипу
М1 ПАМ мають важливу протипухлинну активність, здатні ліквідовувати ракові клітини шляхом продукції сполук і виділяють хемокіни, які рекрутують і преміюють Т-клітини протипухлинного фенотипу, що призводить до затримки росту або регресії пухлини. М2-подібні ПАМ, навпаки, можуть активно сприяти...
2018 / Айкян А.З., Шинкевич В.І., Кайдашев І.П. -
Pathomorphological changes of respiratory department of lungs due to multiple skeletal trauma with the use of intramedullary osteosynthesis in the experiment
Experimental study was carried out on 90 white male Wistar line rats and defined microscopic and ultrastructural changes of the respiratory department of the lung due to multiple skeletal trauma with intramedullary osteosynthesis use in dynamics (6, 24, 72, 168 hours) by lightoptical and electron...
2018 / Zaiats L.M., Kuz U.V. -
Comparative analysis of dental implants stability
Dental implants are increasingly used in oral surgery. Notwithstanding the advancement of the methods for treatment of caries and its complications, the need of population in implant treatment is increasing annually. Currently, permanent impact of various pathogenic factors (cosmic-planetary,...
2018 / Popovych I.Yu., Petrushanko T.O., Yeroshenko G.A., Steblovskiy D.V. -
Экспериментальное применение ксенотрансплантата при операции синуслифтинг
Проведено экспериментальное исследование на беспородных собаках в возрасте 1-2 года массой 8 12 кг. Заготовлен брефоксено-трансплантат из костной ткани новорожденных ягнят, деминерализованный по методу В.И. Савельева и консервированный по методу В.Ф. Парфентьевой. При синуслифтинге применяли...
2019 / Элназаров Азамат Тулкин Угли, Шадиев Саъдулла Самехжанович -
Плазменно-активированные жидкости в противораковой терапии2019 / Кончеков Е. М., Пулиш А. В.
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Bone tissue regeneration of autografts of different origin after defect correction of alveolar process of maxillary in rats
The results of the research of reparative regeneration and course of osteogenesis in autografts of different origin and bone of the alveolar process of the maxillary in 75 rats after its defect are presented. In 2018-2019 at the territory of the Experimental Biological Clinic of the Bogomolets...
2019 / Yakovenko L., Kulynych M., Savytska I. -
Применение биопластических, клеточных и биологических материалов для заживления раневых дефектов
Лечение пациентов с послеоперационными раневыми дефектами и длительно незаживающими раневыми дефектами продолжает оставаться одной из важных проблем в хирургии. Использование достижений в области клеточной биологии позволяет расширить возможности обычных хирургических методик с помощью материалов,...
2019 / Кривощеков Е.П., Аляпышев Г.С., Ельшин Е.Б., Романов В.Е. -
Expression of specific glioma markers and proliferative activity index in tumor tissues of rats at experimental ascariasis and trichinosis
Objective to study the expression of specific glioma markers and indicators of the proliferative activity index in tumor tissues of rats with experimental ascariasis and trichinosis depending on the dose of infection and the duration of observation. Materials and methods. Studies were performed on...
2019 / Pobyarzhin V.