CC BY
10ALT'22
LASER-MATTER INTERACTION
LM-O-4
Thermo-mechanical effect of eye-tissue laser modification.
O.I. Baum
Institute of Photon Technologies, Federal Scientific Research Centre 'Crystallography and Photonics ' of Russian
Academy of Sciences, Troitsk, 108840 Moscow, Russia baumolga@gmail.com
Laser-indused thermo-mechanical effect is a basis of new methods for laser modification of the biological tissue structure. This effect can be useful in normalizing intraocular pressure in correction of refraction [1], treatment of glaucoma [2], laser reshaping of rib cartilage for larynx stenosis surgery [3] and for regeneration processes [4]. The common problem for all these new laser methods is achieving the predicted and stable result.
Earlier the assumption that in the places of the sample, where the greatest thermal stresses were created, is the epicenter of pore formation, was confirmed. In this work the theoretical calculation of thermal stresses was compared with the laser-induced pore-distribution along the direction perpendicular to the laser radiation axis. The experimentally obtained width and position of the maximum size distribution of laser-induced pores in bio-tissue repeated the dynamics obtained theoretically. The obtained verification of the theoretical model demonstrates its potential and will allow it to be further used to predict the result obtained under laser irradiation.
The novelty of the developed approach is associated with the development of the foundations for a new method of diagnosing and monitoring the treatment method for advanced open-angle glaucoma.
References
O. Baum, A. Yuzhakov, A. Bolshunov, et.al., "New laser technologies in ophthalmology for normalisation of intraocular pressure and correction of refraction," Quantum electronics, 47(9), p.860, 2017.
O. Baum, S. Wachsmann-Hogiu, T. Milner, E. Sobol, "Laser-assisted formation of micropores and nanobubbles in sclera promote stable normalization of intraocular pressure," Laser Physics Letters, 14 (6), p.065601, 2017.
O. Baum, Y. Soshnikova, E. Sobol, "Laser reshaping of costal cartilage for transplantation," Lasers in surgery and medicine, 43 (6), pp.511-515 (2011).
Alexandrovskaya, Y. M., Baum, O. I., Shekhter, A. B., Petersen, E. V., Tiflova, O. A., Dmitriev, A. K. & Sobol, E. N. Mechanisms of laser activation of chondrocytes in osteoarthritis healing. Laser Physics Letters, 15(8), 085601 (2018).
