CC BY
16B-O-9
The OCE-assisted monitoring of slow strains in laser-reshaped cartilage implants
Y. Alexandrovskaya1,2, O. Baum1,2, V. Zaitsev1
institute of Applied Physics, Russian Academy of Sciences, Nizhny Novgorod, Russian Federation
2Federal Scientific Research Centre 'Crystallography and Photonics' of Russian Academy of Sciences, Biophotonics laboratory, Troitsk, Moscow, Russian Federation
The infrared laser-induced thermal and stress fields are applied to cartilaginous tissue to perform its reshaping and obtain allo- and autoimplants of new stable curvature [1]. In particular, the medical technology for the larynx stenosis treatment using laser-modified semicircle costal cartilage slices has been developed and tested showing positive results on animals and patients [13]. The most serious side effects are connected with the spontaneous deformation of the implanted tissue causing its poor engraftment. Thus, rapid and non-destructive monitoring of residual stress in cartilage is of utmost importance to control the quality of the laser-reshaped implants. Here we present a technique of the combined OCT-based elastographic measurement to monitor the velocity of the post-irradiational dilatation of costal cartilage implants. We observe post-reshaping slow strains caused by residual unrelaxed stresses. During the operation an unaided eye cannot distinguish such slow, but potentially dangerous strains accompanying unfolding of the semicircular implant. High sensitivity of OCT-based strain mapping makes it possible to detect such strains on intervals ~tens of seconds, which bodes well for intraoperational applications. The cumulative strain kinetics for different time intervals after laser irradiation was analyzed. The criteria for laser-induced relaxation of mechanical stresses in cartilage were formulated. The study was supported by Russian Science Foundation grant 16-15-10274.
References
1. O.I. Baum, Yu.M. Alexandrovskaya, V.M. Svistushkin, S.V. Starostina and E.N. Sobol 2019, Laser Phys. Lett., 16, 035603.
2. E. Sobol, O. Baum, Yu. Alexandrovskaya, A. Shekhter, L. Selezneva, V. Svistuskin 2017, Proc. of
SPIE,10039, 100390U-1.
3. O.I. Baum, Y.M. Soshnikova, E.N. Sobol et al 2011, Lasers Surg. Med., 43, 511.
