Pichugina Yu. A.
The basic level of oxytocin in children's patients suffering from autism spectrum disorders
© PICHUGINA Y. A.
UDC 612.313.1:616.896-053.2
DOI: 10.20333/25000136-2022-2-114
The basic level of oxytocin in children's patients suffering from autism spectrum disorders
Y. A. Pichugina
Prof. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk 660022, Russian Federation
Abstract. A modern assessment of the prevalence of autism spectrum disorders indicates an increase in the number of patients [1]. As a rule, rates up to 3-4 cases per 10,000 of the population reflect the prevalence of typical forms of autistic disorders, such as early childhood autism and Kanner's syndrome [2]. With a broader assessment of other disorders that are included in the group of general disorders of mental development, the prevalence rates increase from 7.6 per 1000 to 157 per 10,000 [3, 4]. A significant increase in patients with childhood and older autism inevitably leads to the actualisation of scientific research on social problems [5].
The aim of the research: to study the social characteristics of patients with autistic disorders of childhood, hospitalised in a psychiatric hospital for the first time.
Results: according to the results of a comparative analysis, children with autism were significantly more have a disability group than children with mental retardation (53.3 % and 13.5 %, p<0.05), and were also significantly less to be social orphans and were fully supported by the state till the time of first hospitalisation (2.6 % and 35.1 %, p<0.05). It was found that a relatively comparable number of children of both groups lived in single-parent families (20.5 % and 25.7 %); statistical significance corresponded to the level of random differences in this indicator. There was a clear trend towards a more prosperous situation for autistic children. Patients with autism spectrum disorder were less likely than those with intellectual disability to be in care (5.1 % vs. 21.6 %) and also less likely to have parents with alcohol or drug addiction (7.7 % vs. 20.3 %). However, the assessment of statistical significance in order to recognise the significant differences between groups in these parameters did not reach a statistically significant level.
Conclusions: it was found that paediatric patients with autism spectrum disorders, who were first hospitalised in a hospital, were significantly more come from a more prosperous family environment than patients with mental retardation. Key words: autism spectrum disorders, mental retardation, social characteristics.
Conflict of interest. The authors declare the absence of obvious and potential conflicts of interest associated with the publication of this article. Citation: Pichugina YA. The basic level of oxytocin in children's patients suffering from autism spectrum disorders. Siberian Medical Review. 2022;(2):2-114. DOI: 10.20333/25000136-2022-2-114
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Author information
Yulia A. Pichugina, Cand.Med.Sci., Associate Professor, Prof. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University; Address: 1, Partizan Zheleznyak Str., Krasnoyarsk, Russian Federation 660022; e-mail: kafedra_pn_@mail.ru , https://orcid.org/0000-000l-839l-821X
Received 24 February 2022 Revision Received 25 February 2022 Accepted 11 March 2022
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Siberian Medical Review. 2022;(2):114