Научная статья на тему 'THE BASIC LEVEL OF OXYTOCIN IN CHILDREN'S PATIENTS SUFFERING FROM AUTISM SPECTRUM DISORDERS'

THE BASIC LEVEL OF OXYTOCIN IN CHILDREN'S PATIENTS SUFFERING FROM AUTISM SPECTRUM DISORDERS Текст научной статьи по специальности «Фундаментальная медицина»

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Ключевые слова
AUTISM SPECTRUM DISORDERS / MENTAL RETARDATION / SOCIAL CHARACTERISTICS

Аннотация научной статьи по фундаментальной медицине, автор научной работы — Pichugina Yulia A.

A modern assessment of the prevalence of autism spectrum disorders indicates an increase in the number of patients [1]. As a rule, rates up to 3-4 cases per 10,000 of the population reflect the prevalence of typical forms of autistic disorders, such as early childhood autism and Kanner's syndrome [2]. With a broader assessment of other disorders that are included in the group of general disorders of mental development, the prevalence rates increase from 7.6 per 1000 to 157 per 10,000 [3, 4]. A significant increase in patients with childhood and older autism inevitably leads to the actualisation of scientific research on social problems [5]. The aim of the research: to study the social characteristics of patients with autistic disorders of childhood, hospitalised in a psychiatric hospital for the first time. Results: according to the results of a comparative analysis, children with autism were significantly more have a disability group than children with mental retardation (53.3 % and 13.5 %, p<0.05), and were also significantly less to be social orphans and were fully supported by the state till the time of first hospitalisation (2.6 % and 35.1 %, p<0.05). It was found that a relatively comparable number of children of both groups lived in single-parent families (20.5 % and 25.7 %); statistical significance corresponded to the level of random differences in this indicator. There was a clear trend towards a more prosperous situation for autistic children. Patients with autism spectrum disorder were less likely than those with intellectual disability to be in care (5.1 % vs. 21.6 %) and also less likely to have parents with alcohol or drug addiction (7.7 % vs. 20.3 %). However, the assessment of statistical significance in order to recognise the significant differences between groups in these parameters did not reach a statistically significant level. Conclusions: it was found that paediatric patients with autism spectrum disorders, who were first hospitalised in a hospital, were significantly more come from a more prosperous family environment than patients with mental retardation.

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Текст научной работы на тему «THE BASIC LEVEL OF OXYTOCIN IN CHILDREN'S PATIENTS SUFFERING FROM AUTISM SPECTRUM DISORDERS»

Pichugina Yu. A.

The basic level of oxytocin in children's patients suffering from autism spectrum disorders

© PICHUGINA Y. A.

UDC 612.313.1:616.896-053.2

DOI: 10.20333/25000136-2022-2-114

The basic level of oxytocin in children's patients suffering from autism spectrum disorders

Y. A. Pichugina

Prof. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk 660022, Russian Federation

Abstract. A modern assessment of the prevalence of autism spectrum disorders indicates an increase in the number of patients [1]. As a rule, rates up to 3-4 cases per 10,000 of the population reflect the prevalence of typical forms of autistic disorders, such as early childhood autism and Kanner's syndrome [2]. With a broader assessment of other disorders that are included in the group of general disorders of mental development, the prevalence rates increase from 7.6 per 1000 to 157 per 10,000 [3, 4]. A significant increase in patients with childhood and older autism inevitably leads to the actualisation of scientific research on social problems [5].

The aim of the research: to study the social characteristics of patients with autistic disorders of childhood, hospitalised in a psychiatric hospital for the first time.

Results: according to the results of a comparative analysis, children with autism were significantly more have a disability group than children with mental retardation (53.3 % and 13.5 %, p<0.05), and were also significantly less to be social orphans and were fully supported by the state till the time of first hospitalisation (2.6 % and 35.1 %, p<0.05). It was found that a relatively comparable number of children of both groups lived in single-parent families (20.5 % and 25.7 %); statistical significance corresponded to the level of random differences in this indicator. There was a clear trend towards a more prosperous situation for autistic children. Patients with autism spectrum disorder were less likely than those with intellectual disability to be in care (5.1 % vs. 21.6 %) and also less likely to have parents with alcohol or drug addiction (7.7 % vs. 20.3 %). However, the assessment of statistical significance in order to recognise the significant differences between groups in these parameters did not reach a statistically significant level.

Conclusions: it was found that paediatric patients with autism spectrum disorders, who were first hospitalised in a hospital, were significantly more come from a more prosperous family environment than patients with mental retardation. Key words: autism spectrum disorders, mental retardation, social characteristics.

Conflict of interest. The authors declare the absence of obvious and potential conflicts of interest associated with the publication of this article. Citation: Pichugina YA. The basic level of oxytocin in children's patients suffering from autism spectrum disorders. Siberian Medical Review. 2022;(2):2-114. DOI: 10.20333/25000136-2022-2-114

References

1. Fombonne E. Epidemiology of pervasive developmental disorders. Pediatric Research. 2009;65(6):591-598. DOI: 10.1203/PDR.0b013e31819e7203

2. Newschaffer CJ, Croen LA, Daniels J, Giarelli E, Grether JK, Levy SE, Mandell DS, Miller LA, Pinto-Martin J, Reaven J, Reynolds AM, Rice CE, Schendel D, Windham GC. The epidemiology of autism spectrum disorders. Annual Review of Public Health. 2007;(28):235-258. DOI: 1146/annurev.publhealth.28.021406.144007

3. Baxter AJ, Brugha TS, Erskine HE, Scheurer RW, Vos T, Scott JG. The epidemiology and global burden of autism spectrum disorders. Med. 2015;45 (3):601-613. DOI: 10.1017/S003329171400172X.

4. He P, Guo C, Wang Z, Chen G, Li N, Zheng X. Socioeconomic status and childhood autism: A population-based study in China. Psychiatry Research. 2018; (259): 27-31. DOI: 10.1016/j.psychres.2017.08.046

5. Ruggieri V, Gomez JLC, Martinez MM, Arberas C. Aging and Autism: Understanding, Intervention, and Proposals to Improve Quality of Life. Current Pharmaceutical Design. Accessed December, 2019. DOI: 10.2174/138161 2825666191204165117

Author information

Yulia A. Pichugina, Cand.Med.Sci., Associate Professor, Prof. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University; Address: 1, Partizan Zheleznyak Str., Krasnoyarsk, Russian Federation 660022; e-mail: kafedra_pn_@mail.ru , https://orcid.org/0000-000l-839l-821X

Received 24 February 2022 Revision Received 25 February 2022 Accepted 11 March 2022

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Siberian Medical Review. 2022;(2):114

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