DOI 10.24412/cl-37136-2023-1-175-175
STRATEGIES FOR AN INDIVIDUALIZED LIGHT DOSIMETRY
THEREZA CURY FORTUNATO1 , VICTOR PORTO GONTIJO DE LIMA2 AND LILIAN TAN
MORIYAMA2
1 Bright Photomedicine Ltda., Brazil 2 Sao Carlos Institute of Physics, University of Sao Paulo, Brazil
ABSTRACT
In Biomedical Optics applications, either for therapy or diagnostics, it is important to establish the best strategy for tissue irradiation. The main difficulties rely on the fact that there are several types of equipment and several types of target tissues. It is noticeable that the best strategy of irradiation is not very simple to determine, and up to our knowledge, the influence of all these different parameters (technological and biological) has not been deeply explored yet. It is not clear, for instance, how light dosimetry for a certain phototherapy can be affected by tissue surface roughness, by the application of a cream or oil during the irradiation, or by the light delivery device. One of the biggest obstacles for establishment of individualized light dosimetry is that experimental measurements of all the features of a targe tissue would require an invasive procedure, like the insertion of an optical fiber, and it is infeasible and impractical. Monte Carlo simulations have been proven to be a powerful toll to assess light propagation through biological tissues. In this presentation we will address strategies our group is exploring to achieve an individualized light dosimetry.
REFERENCES
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