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Genij Ortopedii. 2022. Vol. 28, no. 3. P. 392-399. Гений ортопедии. 2022. Т. 28, № 3. С. 392-399.
Original article
https://doi.org/10.18019/1028-4427-2022-28-3-392-399
Restoration of vertebral body height in traumatic thoracolumbar fractures: open versus minimal invasive surgery - which is better?
M. Mahesh1, T.V. Ravikumar1, N. Harshith2, Hiremaglur Nirdesh3, C.R. Dinakar Reddy4, N. Kotian Ronak1, B. Sneha1,
M. Safia1, Eapen Arun1
1 Ramaiah medical college, Bengaluru, India
2 Sapthagiri Institute of Medical Sciences and Research Centre, Bengaluru, India
3 National Academy of Medical Sciences (NAMS), Bengaluru, India
4 Ramaiah Memorial Hospital, Bengaluru, India
Corresponding author': M. Mahesh, [email protected] Abstract
Background Percutaneous minimally invasive surgery (MIS) has been increasingly implemented to treat thoracolumbar (TL) fracture against a conventional open pedicle screw fixation (OPSF) with desirable radiological and clinical outcomes. Studies in the Indian context are required to determine the efficiency of MIS over OPSF. Objective To compare restoration and maintenance of vertebral body height (VBH) following MIS versus OPSF. Methods A prospective comparative study was conducted in a tertiary care hospital. Patients (n = 36) aged 18-65 years (males = 23, females = 13) with traumatic TL fractures were identified. Eighteen of them underwent OPSF and other eighteen underwent MIS. The radiological outcomes like anterior and posterior vertebral body height percentage (AVBH % and PVBH %) restoration and maintenance were evaluated. Quantitative variables were analyzed and described using mean ± standard deviation and qualitative variables were presented using frequency and percentage. Student t-test was used to analyse continuous data and Chi-square/Fisher Exact test was used to analyse categorical data. Results The mean age of the patients was 38.8 years. The majority of fractures were seen in the T12-LI segment (52.7 %). The AVBH % restoration and maintenance in OPSF was significantly higher compared to that of MIS at immediate post-operative (IPO) period (p = 0.01), 6 weeks (p = 0.02) and 12 weeks (p = 0.006) post-surgery. Long segment stabilization provided statistically significant AVBH and PVBH values for OPSF compared to MIS (p < 0.05). The presence or absence of pedicle screw at fractured vertebral level did not restore AVBH and PVBH to a statistically significant level in both the groups (p > 0.05). Superficial surgical site infection (SSSI) was seen in both the groups without any statistical significance between them (p > 0.05). Conclusion OPSF is superior over MIS in the restoration of AVBH. Restoration of PVBH was also better with OPSF although not statistically significant. OPSF with longer segment fixation had better restoration of both AVBH and PVBH. The presence or absence of pedicle screw at fractured vertebral level did not seem to have any significance in both the groups. However, the MIS approach can be a reasonable alternative to open surgery with potential advantages like better clinical and functional outcome. A selected population of patients treated with MIS will show better surgical outcomes.
Keywords: Minimally Invasive Surgical Procedures, Pedicle Screws, Radiography, Body height, Surgical wound infection, Spine
For citation: Mahesh M., Ravikumar T.V., Harshith N., Nirdesh Hiremaglur, Dinakar Reddy C.R., Ronak N. Kotian, Sneha B., Safia M., Arun Eapen. Restoration of vertebral body height in traumatic thoracolumbar fractures: open versus minimal invasive surgery - which is better? Genij Ortopedii, 2022, vol. 28, no 3, pp. 392-399. https://doi.org/10.18019/1028-4427-2022-28-3-392-399
Научная статья
УДК 616.711.5/.6-001.5-089
Восстановление высоты тел позвонков при травматических переломах грудопоясничного отдела: открытая или малоинвазивная хирургия - что лучше?
M. Mahesh1, T.V. Ravikumar1, N. Harshith2, Hiremaglur Nirdesh3, C.R. Dinakar Reddy4, N. Kotian Ronak1, B. Sneha1,
M. Safia1, Eapen Arun1
1 Ramaiah medical college, Bengaluru, India
2 Sapthagiri Institute of Medical Sciences and Research Centre, Bengaluru, India
3 National Academy of Medical Sciences (NAMS), Bengaluru, India
4 Ramaiah Memorial Hospital, Bengaluru, India
Автор, ответственный за переписку: M. Mahesh, [email protected] Аннотация
Введение. Чрескожная малоинвазивная хирургия (MIS) все чаще применяется для лечения переломов грудопоясничного отдела (TL) по сравнению с традиционной открытой фиксацией транспедикулярными винтами (OPSF) с желаемыми рентгенологическими и клиническими результатами. Исследования в индийском контексте необходимы для определения эффективности MIS по сравнению с OPSF. Цель. Сравнить результаты восстановления и поддержания высоты тела позвонка (VBH) после MIS и OPSF. Материалы и методы. Проспективное сравнительное исследование было проведено в больнице третичного уровня. Отобраны больные (n = 36) в возрасте от 18 до 65 лет (мужчины - 23, женщины - 13) с травматическими переломами TL-позвонков. Восемнадцать из них оперированы по методике OPSF, остальные восемнадцать - MIS. Были оценены рентгенологические результаты, такие как восстановление и поддержание высоты тел позвонков в переднем и заднем отделах в процентном выражении (AVBh % и PVBH %). Количественные переменные были проанализированы и описаны с использованием среднего значения ± стандартное отклонение, а качественные переменные были представлены с использованием частоты и процента. Для анализа непрерывных данных использовался t-критерий Стьюдента, а для анализа категорий-ных данных применялся хи-квадрат/точный критерий Фишера. Результаты. Средний возраст пациентов составил 38,8 года. Большинство переломов наблюдалось в сегменте T12-LI (52,7 %). Процент восстановления и поддержания AVBH при OPSF был значительно выше по сравнению с MIS в ближайшем послеоперационном (IPO) периоде (p = 0,01), через 6 недель (p = 0,02) и 12 недель (p = 0,006) после операции. Стабилизация более протяженного сегмента обеспечила статистически значимые значения AVBH и PVBH при OPSF по сравнению с MIS (p < 0,05). Наличие или отсутствие транспедикулярных винтов на уровне перелома позвонка не влияло на восстанавление AVBH и PVBH до статистически значимого уровня в обеих группах (p > 0,05). Поверхностная инфекция области хирургического вмешательства (SSSI) наблюдалась в обеих группах без какой-либо статистической значимости между ними (p > 0,05). Заключение. OPSF превосходит MIS в восстановлении AVBH. Восстановление PVBH также было лучше при OPSF, хотя и не было статистически значимым. OPSF с более пролонгированной фиксацией сегмента лучше восстанавливала как AVBH, так и PVBH. Наличие или отсутствие транспедикулярных винтов на уровне поврежденных позвонков, по-видимому, не имело никакого значения в обеих группах. Тем не менее, подход MIS может быть
© Mahesh M., Ravikumar T.V., Harshith N., Nirdesh Hiremaglur, Dinakar Reddy C.R., Ronak N. Kotian, Sneha B., Safia M., Arun Eapen, 2022
разумной альтернативой открытой хирургии с потенциальными преимуществами, такими как лучший клинический и функциональный результат. У подобранной популяции пациентов при применении MIS возможны лучшие результаты хирургического вмешательства. Ключевые слова: малоинвазивные хирургические вмешательства, транспедикулярные винты, рентгенография, рост, хирургическая раневая инфекция, позвоночник
Для цитирования: Restoration of vertebral body height in traumatic thoracolumbar fractures: open versus minimal invasive surgery - which is better? / M. Mahesh, T.V. Ravikumar, N. Harshith, Hiremaglur Nirdesh, C.R. Dinakar Reddy, N. Kotian Ronak, B. Sneha, M. Safia, Eapen Arun // Гений ортопедии. 2022. Т. 28, № 3. С. 392-399. https://doi.org/10.18019/1028-4427-2022-28-3-392-399. EDN PYLRUM.
INTRODUCTION
Thoracolumbar (TL) fractures constitute a large spectrum of musculoskeletal injuries ranging from a simple non-displaced fracture to a complex fracture-dislocation [1]. Most TL injuries occur at the T11 to L2 level [2]. Around 50 % of these injuries are unstable and may lead to deformity, disability, neurological deficits that disrupt the quality of life [1]. The causes of TL fracture may vary based on the patient's age. The most common cause in young individuals is high-energy trauma and plunge from a height [1]. Low-energy trauma is the most common cause of osteoporotic fracture in the elderly [3].
Conventional open pedicle screw fixation (OPSF) via posterior approach has been the gold standard surgical method in the treatment of traumatic TL fractures [4]. However, the open technique involves extensive exposure and is associated with postoperative pain as well as early morbidity [1]. The percutaneous minimally invasive surgery (MIS) to treat TL fractures has gained much attention with good radiological and clinical outcomes [5, 6]. The restoration of AVBH and PVBH are the most important radiological parameters assessed following the fixation of TL spine. Pedicle screw fixation through in MIS via the Wiltse approach for the treatment of TL fractures efficiently restores the spine curvature, rebuilds the vertebral body height (VBH), resets the fracture blocks, and achieves three-dimensional fixation without morbidity [4, 7].
Although MIS is an attractive alternative to open surgery, it is still unclear whether MIS restores the VBH comparable to OPSF. Hence, the present study intended to compare the outcomes of MIS versus OPSF with regards to restoration and maintenance of AVBH and PVBH.
Subjects and Methods
This prospective comparative study was conducted on patients admitted to the department of orthopaedics in a tertiary care hospital with traumatic TL fractures from 2016 to 2018. Inclusion criteria were patients aged 18-65 years with traumatic TL fractures. All the patients with absent neurological deficits and those under AO subtypes A1-A4 and B1 were included. Patients with osteoporotic fractures, pathological fractures due to primary tumour/ metastasis, and previous surgery at the site of fracture were excluded. Patients who fulfilled the inclusion criteria were explained clearly about the purpose and nature of the study and written their informed consent was obtained. Ethical clearance was sought from Institutional Ethical and Review board before the study commencement.
The diagnosis of traumatic TL fractures was made based on clinical and radiological evaluation. Basic radiological examinations included antero-posterior and lateral radiographs of the fractured vertebra, Magnetic Resonance Imaging (MRI) of the fractured vertebra +/-Computed Tomography (CT) were done. OPSF for the fractured vertebra was performed in one group (n = 18) and
MIS in the other group (n = 18). All patients underwent the procedure in prone position on Wilson's frame, with the hip and knee in extension - indirectly flexing the pelvis, increasing the lumbar lordosis and thoracic kyphosis, thereby helping in ligamentotaxis and reduction of the fracture. The incision was made centering over the level of injury, and two levels, above and below the injury, were exposed. Without performing laminectomy, the pedicle screws were put in anatomical position, cantilevering of the rod along with sequential distraction and compression between the tulip of the pedicle screws were done to achieve indirect reduction and restoration of the VBH. The postoperative radiological examination was done at followed-ups for a minimum period of 12 weeks.
Patients were evaluated in the immediate postoperative (IPO) period, and at follow-up after weeks 6 and 12. Radiological parameters measured were AVBH and PVBH on lateral radiographs of the spine preoperatively, IPO period and later at 6 and 12 weeks post-operatively. Any complications following two different surgical techniques were followed up and noted. VBH loss was measured using the Anterior Vertebral Body Compression Percentage (AVBC %), consisting of the percentage of anterior vertebral body compression with respect to the average height of the anterior vertebral bodies immediately, cephalad and caudal to the injury level (formula: V2 / [(V1 + V3)/2] x 100 %) [9].
Method 1 Method 2
Method 1 = Anterior/Middle Column Vertebral Body Compression Ratio (VBCR) = AVH/PVH Method 2 = Anterior Vertebral Body Compression Percentage (AVBC%) = V2/[(V1+V3)/2]»100%) AVH = anterior vertebral height PVH = posterior vertebral height
Fig. 1. Surveyed measurement techniques for assessing vertebral
body height loss [9]
Statistical analysis
All the quantitative variables were analyzed and described using mean ± standard deviation. All the qualitative variables were presented using frequency and percentage. Student t-test was used to find the significance of study parameters on a continuous scale between two groups. Chi-square/Fisher Exact test was used to find the significance of study parameters on a categorical scale between two or more groups. Fisher Exact test was used when sample were very small.
RESULTS
The mean age of patients in the OPSF group was younger when compared to patients in the MIS group, with male predominance in both the groups (P = 0.34). Most patients in both groups were diagnosed with a vertebral fracture of T12, followed by L1 and L2. Pedicle screws were inserted at the fracture site in most patients of both the groups. No significant difference was found between both groups with respect to sex, age, injury level, number of levels stabilized, and insertion of screw (P > 0.05; Table 1).
Table 1
Demography and clinical characteristics in each group
Characteristics Group OPSF (n = 18) Group MIS (n = 18) P-value
Age 37.94 ± 11.37 39.67 ± 12.14 0.34
Sex Female 6 (33.33 %) 7 (38.89 %) 0.72
Male 12 (66.67 %) 11 (61.11 %)
L1 5(27.8 %) 4(22.2 %)
L2 4(22.2 %) 2(11.1 %)
L3 3(16.7 %) 1(5.6 %)
L4 0(0 %) 1(5.6 %)
Injured level T12 4(22.2 %) 6(33.3 %) 0.60
T11 2(11.1 %) 1(5.6 %)
T10 0(0 %) 1(5.6 %)
T8 0(0 %) 1(5.6 %)
T5 0(0 %) 1(5.6 %)
Number of level stabilized 3 8 (44.44 %) 10 (55.56 %) 0.50
5 10 (55.56 %) 8 (44.44 %)
Screw at No 8 (44.44 %) 8 (44.44 %) 1
fracture site Yes 10 (55.56 %) 10 (55.56 %)
Notes: MIS - minimally invasive surgery; AVBH - anterior vertebral body height; PVBH - posterior vertebral body height
In the IPO period and at follow-up weeks 6 and 12, both AVBH and percentage AVBH restoration were significantly increased in the OPSF group compared to MIS group; PVBH and the percentage restoration of PVBH was also higher in the OPSF group compared to the MIS group, however, not statistically significant. The major complication in open surgery group was SSSI (11.1 %), whereas implant failure (11.1 %) in the MIS group. Although insignificant, post-surgical complications were fewer in the open surgery group as compared to the MIS group (P > 0.05; Table 2).
The percentage of AVBH and PVBH restoration in the IPO period, at weeks 6 and 12 compared with regards to number of levels stabilized is given in Table 3 and Figures 2-4. The percentage of restoration of AVBH and PVBH in longer segment fixation (5 levels) at IPO period, weeks 6 and 12 was statistically significant in the OPSF group. However, percentage restoration of AVBH in the MIS group was higher in short segment fixation at IPO period, 6 weeks, and 12 weeks although not statistically significant (Table 3) whereas percentage
restoration of PVBH at IPO period, 6 weeks, and 12 weeks was higher in long segment fixation, although not statistically significant when comparing short and long segment fixation.
Table 2
Comparison of AVBH, PVBH, restoration of AVBH, restoration of PVBH, complications in both groups after surgery
Characteristics OPSF MIS P-value
AVBH Pre-operation 67.84 ± 7.59 69.45 ± 11.63 0.71
IPO period 82.01 ± 7.43 78.92 ± 9.92 0.01*
6 weeks 80.19 ± 7.50 77.7 ± 9.81 0.04*
12 weeks 79.15 ± 7.32 76.68 ± 9.81 0.04*
% Restoration of AVBH Post-op 14.17 ± 5.48 9.48 ± 5.13 0.01*
6 weeks 12.38 ± 4.95 8.25 ± 4.95 0.02*
12 weeks 11.31 ± 4.62 7.24 ± 4.70 0.006**
PVBH Pre-op 93.17 ± 4.32 92.97 ± 2.47 0.56
Post-op 95.61 ± 3.02 95.18 ± 2.53 0.79
6 weeks 95.14 ± 3.41 94.70 ± 2.35 0.06
12 weeks 94.95 ± 3.46 94.51 ± 2.39 0.12
% Restoration of PVBH Post-op 2.44 ± 2.21 2.21 ± 1.76 0.74
6 weeks 1.97 ± 1.75 1.73 ± 1.22 0.85
12 weeks 1.78 ± 1.57 1.54 ± 1.14 0.15
Complications No 16 (88.89 %) 15 (83.33 %) 0.31
Implant failure 0 2 (11.11 %)
SSSIs 2 (11.11 %) 1 (5.56 %)
Notes: MIS - minimally invasive surgery; AVBH - anterior vertebral body height; PVBH - posterior vertebral body height
Table 3
Number of levels stabilized with % restoration (AVBH and PVBH) in both groups
Group % restoration Number of levels stabilized P-value
3 5
AVBH
IPO period 11.13 ± 1.98 16.61 ± 6.24 0.000***
6 weeks 10.22 ± 2.96 14.11 ± 5.67 0.000***
OPSF 12 weeks 9.34 ± 2.87 12.88 ± 5.27 0.015*
PVBH
IPO period 0.93 ± 1.25 3.64 ± 2.09 0.000***
6 weeks 0.87 ± 1.24 2.85 ± 1.64 0.010*
12 weeks 0.78 ± 1.08 2.58 ± 1.47 0.000***
AVBH
IPO period 10.33 ± 5.62 8.43 ± 4.58 0.98
6 weeks 8.93 ± 5.56 7.41 ± 4.25 0.97
MIS 12 weeks 7.79 ± 5.19 6.53 ± 4.25 0.68
PVBH
IPO period 1.97 ± 1.11 2.51 ± 2.39 0.27
6 weeks 1.57 ± 0.79 1.95 ± 1.64 0.16
12 weeks 1.38 ± 0.73 1.64 ± 1.55 0.08
Notes: MIS - minimally invasive surgery; AVBH - anterior vertebral body height; PVBH - posterior vertebral body height
Fig. 2. X-rays of a 49-year old female patient with T11 fracture who underwent T9-L1 MIS 5 level stabilization without screw at fracture site: pre-operative AVBH and PVBH (a, b); IPO AVBH and PVBH (c, d); post-operative AVBH and PVBH at 6 weeks (e, f), and at 12 weeks (g, h)
*
Fig. 3. X-rays of a 58-year old female patient with L1 fracture who underwent T12-L2 open 3 level surgery with screw stabilization fracture site: pre-operative AVBH and PVBH (a, b); IPO AVBH and PVBH (c, d); post-operative AVBH and PVBH at 6 weeks (e, f), and at 12 weeks (g, h)
í 3
Fig. 4. X-rays of a 42-year old female patient with T8 fracture who underwent T7-T9 MIS 3 level stabilization with screw at fracture: preoperative anterior vertebral body height and PVBH (a, b); IPO AVBH and PVBH (c, d); post-operative AVBH and PVBH at 6 weeks (e, f) and, at 12 weeks (g, h)
The percentage restoration of AVBH and PVBH at IPO period, 6 weeks, and 12 weeks compared with regards to the presence or absence of screw at the fractured vertebral level in both groups is tabulated in Table 4. The percentage restoration of AVBH was higher in patients with a screw at the fractured vertebral level compared to patients without a screw in both OPSF and MIS groups, although not statistically significant. The percentage restoration of PVBH was higher in patients without a screw at fractured vertebral level in both groups (Table 4), although not statistically significant (Fig. 5-9).
A 23-year-old male patient (Fig. 5) with T12 fracture: T10-L2 open surgery with 5-level stabilization without screw fixation at the fracture site was done (Fig. 6). Pre-operative AVBH (Fig. 6, a) (in millimeter) = 12/(26.3+26.9)/2 = 12/26.6 = 45.11 %. Pre-operative PVBH (Fig. 6, b) (in millimeter) = 25.8/(26.2+28.3)/2 = 25.8/27.25 = 94.67 %. Post-operative AVBH: 25/26.6 = 93.98 % (Fig. 7, b), or 48.87 % restoration compared to preoperative AVBH; postoperative PVBH 26.8/27.25 = 98.34, or 3.67 % restoration compared to preoperative PVBH. Post-operative X-rays AP and lateral views (Fig. 7). Post-operative AVBH at 6 weeks (Fig. 8): 24.7/26.6 = 92.85 %, or 47.74 % restoration compared to preoperative AVBH; post-operative PVBH at 6 weeks: 26.8/27.25 = 98.34 %, or 3.67 % restoration compared to preoperative PVBH; 6 weeks post-operative X-rays AP and lateral views (Fig. 8, a, c). 12-weeks postoperative AVBH: 24.7/26.6 = 92.85 %, or 47.74 % restoration compared to preoperative AVBH (Fig. 9, b); 12-weeks post-
operative PVBH: 26.8/27.25 = 98.34, or 3.67 % restoration compared to preoperative PVBH; 12-weeks post-operative X-rays AP and lateral views (Fig. 9, a, c).
Table 4
Screw at fracture site with % restoration (AVBH and PVBH) in each group (OPSF and MIS)
Group % Restoration Screw at fracture site P value
No Yes
AVBH
IPO period 14.43 ± 6.01 13.96 ± 5.34 0.75
6 weeks 12.35 ± 5.75 12.40 ± 4.54 0.34
OPSF 12 weeks 11.18 ± 5.49 11.42 ± 4.12 0.90
PVBH
IPO period 3.18 ± 2.55 1.84 ± 1.81 0.05
6 weeks 2.46 ± 1.93 1.58 ± 1.59 0.08
12 weeks 2.18 ± 1.68 1.46 ± 1.48 0.47
AVBH
IPO period 8.03 ± 4.53 9.65 ± 5.51 0.19
6 weeks 7.06 ± 4.95 8.21 ± 4.98 0.07
MIS 12 weeks 5.92 ± 4.72 8.28 ± 4.66 0.51
PVBH
IPO period 2.21 ± 2.03 2.22 ± 1.62 0.06
6 weeks 1.77 ± 1.33 1.71 ± 1.19 0.94
12 weeks 1.51 ± 1.22 1.57 ± 1.14 0.1474
Notes: MIS - minimally invasive surgery; AVBH - anterior vertebral body height; PVBH - posterior vertebral body height
Fig. 5. Pre-operative AP (a) and lateral (b) X-rays of the patient
Fig. 6. Pre-operative AVBH (a) and PVBH (b) of the patient
Fig. 7. IPO X-rays and AVBH and PVBH restoration of the patient
Fig. 8. 6-weeks post-operative X-rays and AVBH and PVBH restoration of the patient
Fig. 9. 12-weeks post-operative X-rays and AVBH and PVBH restoration of the patient
DISCUSSION
The advent of MIS represents one of the most important advances in surgery during recent times. Compared to OPSF, the MIS has more advantages clinically such as reduced blood loss, operative time, hospital stay and rehabilitation with less soft tissue damage [2, 11]. Percentage restoration of VBH was comparable between MIS and OPSF in a previous study [13]. However, in the present study it was found that OPSF was better for VBH restoration especially with respect to AVBH restoration and maintenance when compared to percutaneous MIS. The technical limitation of MIS instruments currently available for maneuverability to restore the VBH, and with intact paraspinal muscle and soft tissue of the posterior column in MIS may hinder complete distraction of the anterior column.
The mean age of the patients was 38.8 years with male predominance (12:6 in the open surgery and 11:7 in MIS group). Similarly, Khurjekar et al [12] in their study reported a male to female ratio of 8:1 and the mean age of patients to be 32 years. High exposure of adult males to outdoor and physical activities is the reason behind the high incidence of thoracolumbar fractures in the male population. It has been well documented that being a biomechanically unstable segment, more than 50 % of fractures occur in T12-L1 region and similar findings were also observed in this study [12].
The present study demonstrates the advantages of OPSF over MIS in several aspects. AVBH and its percentage restoration was higher significantly in OPSF group when compared to MIS group in IPO period, at 6 and 12 weeks respectively when compared to their pre-operative values. On the contrary, other studies have reported that both OPSF and MIS brought significant improvement in AVBH compared to pre-operative data [10, 13]. A retrospective study by Zhao et al. [14] reported
that AVBH increased significantly post-operatively when compared to pre-operative levels and the loss of AVBH in the group with screw fixation at the fractured vertebra was significantly less than in the group without screw fixation at the fractured vertebra after one-year follow-up period with open approach. However, the presence or absence of pedicle screw at fractured vertebral level did not seem to have any difference in both the groups in our study.
Previous study [15] demonstrated that the percentage of AVBH restoration was better in the long segment than in the short segment, while a few other studies reported that both long and short segment fixations had similar outcomes in terms of post-operative pain relief [16,17]. In the present study, long segment stabilization (5 levels) gave better restoration and maintenance of both AVBH and PVBH in the OPSF group. The longer the segment of fixation, the longer is the lever arm for correction and hence it results in better restoration of VBH.
Previous studies reported that post-operative complications are fewer with the MIS approach than the conventional OPSF for TL fractures [18-20]. In this study, SSSI was the most common complication in both groups and, although statistically insignificant, two implant failures were seen in the MIS group.
Certainly, the study has a few limitations. First, we evaluated the AVBH and PVBH using standard radiographs. Computed tomography is the best modality to assess the AVBH and PVBH especially for post-operative assessment. Second, this was purely a radiological comparison and no functional outcome scores were assessed. Third, the study sample size was quite small with a short term of follow up. Hence studies with a larger sample size with long term follow-up are needed to validate the current findings, with specific number of participants for every fracture type.
CONCLUSIONS
1. OPSF is superior over MIS in the restoration of AVBH.
2. Restoration of PVBH was also better with OPSF, although not statistically significant.
3. OPSF with longer segment fixation had better restoration of both AVBH and PVBH whereas number of levels of fixation did not have any effect in the MIS group.
4. The presence or absence of pedicle screw at fractured vertebral level did not seem to have any difference in both the groups.
5. However, the MIS approach can be a reasonable alternative to open surgery with potential advantages like better clinical and functional outcomes. A selected population of patients treated with MIS might show better surgical outcomes.
6. RCTs or prospective cohort studies, which avoid selection and experimental bias and with controls for confounding factors, are necessary to adequately evaluate this question further before the routine application can be recommended.
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The article was submitted 15.01.2021; approved after reviewing 09.03.2022; accepted for publication 28.03.2022.
Статья поступила в редакцию 15.01.2021; одобрена после рецензирования 09.03.2022; принята к публикации 28.03.2022.
Information about the authors:
1. M. Mahesh - Dr., [email protected], https://orcid.org/0000-0001-9365-3438;
2. T.V. Ravikumar - Dr., [email protected], https://orcid.org/0000-0001-6430-858X;
3. N. Harshith - Dr., [email protected], https://orcid.org/0000-0001-6090-7016;
4. Hiremaglur Nirdesh - Dr., [email protected];
5. C.R. Dinakar Reddy - Dr., [email protected];
6. N. Kotian Ronak - Dr., [email protected], https://orcid.org/0000-0001-9268-9674;
7. B. Sneha - [email protected];
8. M. Safia - [email protected];
9. Eapen Arun - [email protected].
Conflicts of interest Authors declare no conflicts of interest.
