Научная статья на тему 'REPRODUCTIVE STATUS OF WOMEN OF ADVANCED MATERNAL AGE'

REPRODUCTIVE STATUS OF WOMEN OF ADVANCED MATERNAL AGE Текст научной статьи по специальности «Фундаментальная медицина»

CC BY
1
0
i Надоели баннеры? Вы всегда можете отключить рекламу.
Журнал
World science
Ключевые слова
women of advanced maternal age / infertility / medical and social characteristics

Аннотация научной статьи по фундаментальной медицине, автор научной работы — Orenchuk I.V., Boichuk O.H.

The purpose of the study: to study, evaluate and comparative analysis of the causes of reproductive health disorders, to identify socio-hygienic characteristics of women of late reproductive age with infertility. Materials and methods. The study was performed continuously, included 1297 women who underwent infertility treatment by in vitro fertilization from 2019 to 2021. at the state IVF center. Of these, the basic group 530 women of late reproductive age (35-49 years), average age 37.01 + 2.02 years. The comparison group included 767 women with infertility aged 2035 years, average age 30 + 2.79 years. The medical status of patients was assessed according to a comprehensive objective examination. Social status based on the results of the survey. Results. We have found significant differences in the causes of infertility in women of advanced maternal age (from 35 to 49 years) in comparison with infertile women age below 35 years. The predominant causes of infertility in the basic group are the combined factor (42%), multiple female factors (20%) and reduced ovarian reserve (17%). A significantly smaller percentage of women presented the absolute tubal factor (6%) or no gynecological pathology but isolated male factor infertility (9%). The comparative analysis of the social status of the women from the basic and the reference group has found no fundamental differences. Conclusions. Significant differences in the causes of infertility in women of advanced maternal age, the frequency of labors, the assessment of the social situation of infertile women of advanced maternal age are the basis for the development of ways of optimization of the specialized medical assistance for infertile couples and the improvement of the efficiency of treatment.

i Надоели баннеры? Вы всегда можете отключить рекламу.
iНе можете найти то, что вам нужно? Попробуйте сервис подбора литературы.
i Надоели баннеры? Вы всегда можете отключить рекламу.

Текст научной работы на тему «REPRODUCTIVE STATUS OF WOMEN OF ADVANCED MATERNAL AGE»

REPRODUCTIVE STATUS OF WOMEN OF ADVANCED MATERNAL AGE

Orenchuk I. V., postgraduate student at the Subdepartment of Obstetrics and Gynecology of the Department of Postgraduate Studies of Ivano-Frankivsk National Medical University ORCIDID: https://orcid.org/0000-0002-3693-5671

Boichuk O. H., MD, professor at the Subdepartment of Obstetrics and Gynecology ofIvano-Frankivsk National Medical University, ORCID ID: https://orcid.org/0000-0003-4439-3099

DOI: https://doi.org/10.31435/rsglobal_ws/30122021/7728

ABSTRACT

The purpose of the study: to study, evaluate and comparative analysis of the causes of reproductive health disorders, to identify socio-hygienic characteristics of women of late reproductive age with infertility. Materials and methods. The study was performed continuously, included 1297 women who underwent infertility treatment by in vitro fertilization from 2019 to 2021. at the state IVF center. Of these, the basic group - 530 women of late reproductive age (35-49 years), average age - 37.01 + 2.02 years. The comparison group included 767 women with infertility aged 2035 years, average age - 30 + 2.79 years. The medical status of patients was assessed according to a comprehensive objective examination. Social status -based on the results of the survey.

Results. We have found significant differences in the causes of infertility in women of advanced maternal age (from 35 to 49 years) in comparison with infertile women age below 35 years. The predominant causes of infertility in the basic group are the combined factor (42%), multiple female factors (20%) and reduced ovarian reserve (17%). A significantly smaller percentage of women presented the absolute tubal factor (6%) or no gynecological pathology but isolated male factor infertility (9%). The comparative analysis of the social status of the women from the basic and the reference group has found no fundamental differences. Conclusions. Significant differences in the causes of infertility in women of advanced maternal age, the frequency of labors, the assessment of the social situation of infertile women of advanced maternal age are the basis for the development of ways of optimization of the specialized medical assistance for infertile couples and the improvement of the efficiency of treatment.

Citation: Orenchuk I. V., Boichuk O. H. (2021) Reproductive Status of Women of Advanced Maternal Age. World Science. 11(72). doi: 10.31435/rsglobal_ws/30122021/7728

Copyright: © 2021 Orenchuk I. V., Boichuk O. H. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

Women's reproductive health is of crucial importance for the well-being of women

ARTICLE INFO

Received: 28 October 2021 Accepted: 17 December 2021 Published: 30 December 2021

KEYWORDS

women of advanced maternal age, infertility, medical and social characteristics.

.

Therefore, one should monitor women's health, detect gynecological and extragenital pathologies

The purpose of the study: to study, evaluate and comparative analysis of the causes of reproductive health disorders, to identify socio-hygienic characteristics of women of late reproductive age with infertility.

Materials and methods. The study was performed continuously, included 1297 women who underwent infertility treatment by in vitro fertilization from 2019 to 2021. at the state IVF center. The women were divided into two groups: the basic group of 530 women of advanced maternal age (from 35 to 49 years, average age 37.01 + 2.02 years, percentage of primary infertility

) and the reference group of 767 infertile women aged between 20 and 35 (average age 30 + 2.79 years, percentage of primary infertility

of infertility 5.2 + 3.35 years). The patients' medical status was assessed on the basis of the data of a complex objective examination: consultations with specialists, instrumental and laboratory examinations. The assessment of gynecological morbidity included the general morbidity level, the structure of morbidity, the remoteness or duration of a pathological process, the combination of pathologies and the peculiarities of women's chronic morbidity. The patients' social status was assessed on the basis of the results of questionnaires and interviewing of women.

The results of this study suggest that there are significant differences in causes of infertility in women of late reproductive age (35 - 49 years) compared with women of reproductive age with infertility up The predominant cause of infertility in the basic group is the combined factor - 42% (35% in the reference group) multiple female factors

(20%) (7% in the reference group) reduced ovarian reserve (17%)

(0% in the reference group) . A significantly smaller percentage of women of advanced

maternal age presented the absolute tubal factor (6%) (26% in the reference group)

or no gynecological pathology but isolated male factor infertility (9%) (21% in the reference group) . No significant differences between the groups have been found in such

causes of infertility as endometriosis, ovulatory dysfunction, infertility of uncertain genesis

less often than in primary infertility. Patients with secondary infertility who have children are 3.4

compared with infertile women who do not have children. Severe depression is found in every fourth

reproductive age with endometrial pathology are much less likely to be depressed and more likely to have such personality traits as sociability, extraversion and masculinity; patients with primary infertility are more prone to spontaneous aggression, shyness, emotional lability compared to secondary infertility; dysfunctional personality traits are least common in patients with secondary infertility; the personality profile of secondary infertile women who have children is close to the personality profile of fertile patients of late reproductive age with endometrial pathology.

world who are not planning a pregnancy at this stage of their lives are increasingly interested in the

Conclusions. The problem of infertility among women of late reproductive age remains

Special differences in the causes of infertility in women of advanced maternal age, the assessment of the social situation of infertile women of advanced maternal age are the basis for the development of ways of optimization of the specialized medical assistance for infertile couples and the improvement of the efficiency of treatment.

REFERENCES

1. Henyk, N.I., & Yakymchuk, N.V. (2018). Modyfikatsiia prohramy prekontseptsiinoi pidhotovky na etapi planuvannia vahitnosti iz vrakhuvanniam psykhoemotsiinoho stanu zhinok [Modification of the pre-conceptional treatment program at the stage of pregnancy planning regarding the psychoemotional state of women]. Simeina medytsyna - Family Medicine, 5 (79), 128-131 [in Ukrainian].

2. Henyk, N.I., Yakymchuk, N.V., & Nesterak, R.V. (2012). Vyvchennia psykholohichnoi hotovnosti do materynstva v systemi psykhoprofilaktychnoi roboty po pidhotovtsi vahitnoi zhinky do polohiv [Study of psychological readiness for motherhood in the system of psychoprophylactic work to prepare a pregnant woman for childbirth]. Proceedingsof:Rehionalnoi nauk.-prakt. konf. «Psykhosomatychna medytsyna -shliakhy rozvytku» - Regional Scientific PracticalConference "Psychosomatic medicine - ways of development". Ivano-Frankivsk [in Ukrainian].

3. Dobryakov, I.V. (2014). Retrospektivnoye opredeleniye osobennostey psikhologicheskogo komponenta gestatsionnoy dominanty [Retrospective determination of the features of the psychological component of gestational dominance]. Voprosy psikhicheskogo zdorovya detey i podrostkov - Mental Health Issues in Children and Adolescents, 2, 71-75 [in Russian].

4. Znamenskaya, S.I., Kiselev, A.G., Shapovalova, Ye.A., & Maksimova, I.M. (2012). Osobennosti izmeneniy struktury psikhoemotsionalnoy sfery u zhenshchin po trimestram beremennosti [The peculiarities of changes in the structure of psychoemotional sphere in women during the gestation flavors of pregnanc]. Zhurnal akusherstva i zhenskikh bolezney - J. Obstet. Women's Dis., LXI, 6, 30-35 [in Russian].

5. Kaminskiy, V.V., Genyk, N.I., Tkachuk, R.R., Herych, P.R., & Strimbitskiy, V.V. (2018). Vehetatyvni ta psykhosomatychni rozlady u zhinok pid chas vahitnosti [Autonomic and psychosomatic disorders in women during pregnancy]. Simeina medytsyna - Family Medicine, 3 (77),129-137 [in Ukrainian].

6. Lytvynenko, N.V., Purdenko, T.Y., & Ostrovskaya, L.Y. (2015). Vehetatyvnyi ta psykhoemotsiinyi status zhinok u dynamitsi vahitnosti [Vegetative and psycho-emotional status of women in the course of pregnancy]. Simeina medytsyna - Family Medicine, 3 (59), 51-53 [in Ukrainian].

7. Lokhina, Ye.V., & Kachalina, T.S. (2013). Vliyaniye mediko-psikhologicheskoy podgotovki k rodam po programme «Schastlivoye materinstvo» na psikhoemotsionalnoye sostoyaniye zhenshchin v period beremennosti [The influence of medical and psychological preparation for childbirth under the program "Happy Motherhood" on the psycho-emotional state of women during pregnancy]. Meditsinskiy almanakh - Medical Almanac, 2 (26), 199-202 [in Russian].

8. Nikiforova, T.V., Agarkova, L.A., & Schastnyy, Ye.D. (2015). Ispolzovaniye standartizirovannykh shkal pri otsenke effektivnosti kognitivnoy psikhoterapii vo vremya beremennosti u depressivnykh patsiyentov s poterey ploda v anamneze [The use of standardized scales when evaluating the effectiveness of cognitive psychotherapy during pregnancy, depressed patients with loss of the fetus in history]. Uspekhi sovremennogo yestestvoznaniya - Advances Curr. Nat. Sci.,1 (6), 932-936 [in Russian].

9. Syusyuka, V.G. (2017). Otsinka parametriv vehetatyvnoho balansu ta aktyvnosti rehuliatornykh system u vahitnykh z urakhuvanniam yikh psykhoemotsiinoho stanu [Parameters estimation of vegetative balance and activity of regulatory systems of pregnant women in view of their psychoemotional state]. Perinatolohiia i pediatriia - Perinatology and Pediatrics, 2 (70), 64-68. DOI: 10.15574/pp.2017.70.64 [in Russian].

10. Syusyuka, V.G. (2016). Otsinka vplyvu prohramy medyko-psykholohichnoi korektsii psykhoemotsinoi dezadaptatsii u vahitnykh na perynatalni naslidky yikh rozrodzhennia [Estimation of influence of introduced program of medical and psychological correction of psychoemotional disadaptation of pregnant women on perinatal consequences of their delivery]. Perinatolohiia i pediatriia - Perinatology and Pediatrics, 3 (67), 43-48 DOI: 10.15574/PP.2016.67.43 [in Ukrainian].

11. Torchinov, A.M., Umakhanova, M.M., Doronin, G.L., Dzhonboboyeva, G.N., & Ron, M.G. (2013). Problema poteri beremennosti - diagnostika, vedeniye beremennosti, lecheniye i prognozy na sovremennom etape razvitiya akusherstva (obzor literatury) [Problem of pregnancy loss: diagnostics, pregnancy observation, treatment and forecasting at the modern stage of development of midwifery (literature review)]. Lechashchiy vrach - Attending Physician, 9, 85-91 [in Russian].

12. Filinov, A.G. (2016). Kardioritmogramma v otsenke vegetativnoy nervnoy sistemy v razlichnyye sroki normalno protekayushchey beremennosti [Cardiorhythmogramme in evaluation of vegetative nervous system within different terms of normal course of pregnancy]. Meditsinskiy almanakh - Medical Almanac, 5 (45), 55-58 [in Russian].

13. Filippova, G.G. (2015). Prenatalnyy stress: usileniye riska pri sovremennykh tekhnologiyakh vedeniya beremennosti i lecheniya besplodiya [Prenatal stress: increased risk with modern technologies of pregnancy management and infertility treatment]. Proceedings of thelnternational Scientific Conference: «Psikhologycheskiye problemy sovremennoy semi» -"Psychological Problems of the Modern Families". Moscow - Zvenigorod (pp. 418-426) [in Russian].

14. Allaire, A.D. (2014). Placenta apoptosis in preeclampsia. Obstet. Gynecol.,96 (2), 271-276. DOI: 10.1016/s0029-7844(00)00895-4.

15. Ananth, C.V. (2014). Ischemic placental disease: a unifying concept forpreeclampsia, intrauterine growth restriction, and placental abruption. Semin. Perinatol.,38 (3), 131-132. DOI: 10.1053/j.semperi.2014.03.001.

16. Anderson, G., & Maes, M. (2013). Postpartum depression: psychoneuroimmunological underpinnings and treatment. Neuropsychiatr. Dis. Treat.,9, 277. DOI: 10.2147/NDT.S25320.

17. Bartsch, E., Medcalf,K.E., Park,A.L., &Ray,J.G. (2016). Clinical risk factors for preeclampsia determined in earlypregnancy: systematic review and meta-analysis of large cohort studies. BMJ,353, i1753. DOI: 10.1136/bmj.i1753.

18. Blankley, G., Galbally, M., Snellen, M., Power, J., &Lewis,A.J. (2015). Borderlinepersonality disorder in the perinatal period: early infant and maternal outcomesAustralas Psychiatry., 23 (6), 688-692. DOI: 10.1177/1039856215590254.

19. Bogaerts, A.F., Devlieger, R., Nuyts, E., Witters, I., Gyselaers, W., Guelinckx, I., &Van den Bergh, B.R.H. (2013). Anxiety and depressed mood in obese pregnant women: a prospective controlledcohort study. Obes. Facts., 6 (2), 152-164. DOI: 10.1159/000346315.

i Надоели баннеры? Вы всегда можете отключить рекламу.