REGRESSION MODELS OF RHEOENCEPHALOGRAPHIC INDICES, DEPENDING ON THE ANTHROPO-SOMATOMETRIC PARAMETERS OF THE BODY IN PRACTICALLY HEALTHY WOMEN WITH ENDO-MESOMORPHIC SOMATOTYPE

The article describes and analyzes regression models of individual indicators of cerebral circulation in practically healthy women of the endo-mesomorphic somatotype, depending on the features of anthropo-somatotypological indicators. Constructed all 5 possible time indices of rheoencephalogram with determination coefficient (R2) from 0.593 to 0.904; of the 5 possible amplitude indices of the rheoencephalogram, 3 of R2 from 0.540 to 720 were constructed; of the 8 possible derivatives of the rheoencephalogram, 7 with R2 from 0.528 to 0.865 were constructed. Constructed models with R2 more than 0.5 most often include: for amplitude rheoencephalogram indicators - body diameters (29,4%), cephalometric indices and thickness of skin and fat folds (by 23,5%); for the time indices of the rheoencephalogram - the thickness of skin and fat folds (35.7%), cephalometric indices (21.4%), longitudinal, circumferential dimensions and diameters of the body (by 10.7%); for derivative indices of the rheoencephalogram - the thickness of skin and fat folds (29.3%), the circumferential size of the body and the width of distal epiphyses of long limb bones (by 17.1%) and body diameters (14.6%).

with the scheme of V. V. Bunak [3]. Craniometry included a definition: the girth of the head (glabella), sagittal arc, the largest length and width of the head, the smallest head width, face width and mandible [1]. The somatotype is determined by the method of J. Carter and B. Heath [10], and the component composition of the mass of the body -by the method of J. Matiegka [16] and additionally the muscle component -according to the formulas of the American Institute of Nutrition (AIN) [14]. The construction of regression models of individual indicators of cerebral circulation, depending on the anthropo-somatometric parameters of the body of practically healthy women of the endo-mesomorphic somatotype (n = 27), was performed in the -STATISTICA 6.0‖ licensed statistical package.
Results and its discussion. Constructed trustworthy models of individual indicators of cerebral circulation in practically healthy women of the endo-mesomorphic somatotype with a determination coefficient R2 of greater than 0.5 have the following linear equations (in the equations below F is Fisher's criterion, Std. Error of estimation is the standard error of regression estimation): -EZ (base impedance) = 51,81 -5,251 × thickness of the skin-fat fold (TSFF) on the forearm -7,197 × shoulder circumfluence in a tense state + 97,01 × body surface area + 22,26 × face width -4,585 × transverse averaged breast size -10.00 × width of mandible + 2.367 × shoulder width (R2=0.754; F(7,19)=8,31; p<0,001; Std. Error of estimate: 8,347); -EC (duration of the heart cycle) = 2,488 + 0,060 × TSFF on the shoulder front -0,040 × foot circumference -0,037 × head girth + 0,047 × width of the lower jaw + 0,020 × sagittal head arch -0,012 × TSFF on the back of the shoulder (R2=0. components of the somatotype -in marks, indicators of the component weight of the body -in kg. Reliable models with a determination coefficient R2 of less than 0.5 (correspondingly, R2 = 0.330, 0.316, 0.478) for the indicators of the systolic wave amplitude and fast blood flow and the average speed of slow blood flow have been constructed and therefore, these models are not essential for practical medicine.
Thus, with the coefficient of determination more than 0.5, the following models were constructed: from 5 possible amplitude rheoencephalogram parameters -3 with determination coefficient R2 from 0.540 to 720; all 5 possible time rheoencephalograms with determination coefficient R2 from 0.593 to 0.904; from 8 possible derivatives of the rheoencephalogram -7 with a determination coefficient R2 from 0.528 to 0.865. Constructed models most often included: for amplitude indices of rheoencephalograms -body diameters (29.4%), cephalometric indices and TSFF (by 23.5%); for the time indices of the rheoencephalogram -TSFF (35.7%), cephalometric indices (21.4%), longitudinal, circumflex dimensions and body diameters (by 10.7%); for derivative indices of rheoencephalogram -TSFF (29.3%), the circumferential size of the body and the width of distal epiphyses of long limb bones (17.1%) and body diameters (14.6%). The solution of the tasks of preventive and evidence-based medicine is impossible without scientifically substantiated methods of mathematical modeling of functional indicators taking into account the individual-typological features of the organism. This is understandable because the functional capabilities of human cerebral vessels are the result of the interaction of innate neurophysiological status and external influences, the adaptation of which forms the current morphofunctional state specific for individuals of different typological categories [7,9,19]. Traditionally, the morphological criterion -in the form of a somatotype -is taken as the basis for the distinction of types of constitution, since the signs of morphotype are combined with features of a functional organization, parameters of "psychotype", peculiarities of the organization of metabolism, and motor capabilities. As a result, the somatotype is regarded as the main "informer" about the nature of the human constitution [17].The results of constructing regression models of individual indicators of cerebral circulation according to the anthropo-somatometric parameters of the body in women of the endomesomorphic somatotype differ from the results of mesomorphic (in which 3 models of amplitude parameters with determination coefficient R2 from 0.517 to 0.573; only 2 models of time indices with determination coefficient R2 0.613 and 0.582; only one model of derivative with determination coefficient R2 0.509. Constructed models of amplitude and temporal rheoencephalograms parameters most often included circumferential body sizes, cephalometric indexes, TSFF and body diameters) [21] and ectomorphic somatotypes (in which all five models of amplitude indices with a determination coefficient R2 from 0.799 to 0.906 were constructed; all 8 derivative indicators with determination coefficient R2 from 0,733 to 0,909; 4 out of 5 possible time indices with determination coefficient R2 from 0,820 to 0,842. Constructed models most often included: for the time indicators -the circumferential dimensions of the body, TSFF, cephalometric indices and diameters of the body; and for amplitude and derivative indices -the width of the distal epiphyses of the long tubular bones of the extremities in additionally) [11].
Consequently, the typological features of the regression equations confirm the conclusion that representatives of each type of body structure should be regarded as a separate general aggregate. This means that the positive basis for mathematical modeling should be consistent with constitutional features, rather than the results obtained with respect to the entire sample being studied.

Conclusions
1. In the practically healthy women of the endo-mesomorphic somatotype, 15 of the 18 possible models of the studied parameters of cerebral circulation were constructed on the basis of their anthropometric, somatotypological and body composition components with a determination coefficient of R2 greater than 0.5 (3 models of amplitude indices with R2 from 0.540 to 720; all 5 possible time indices with R2 from 0.593 to 0.904; 7 models of rheoencephalograms index derivatives with R2 from 0.528 to 0.865). 2. Among the anthropo-somatotypological indicators, models of amplitude indicators of the rheoencephalogram most often include the diameters of the body (29.4%), cephalometric indices and TSFF (23.5%); to the models of the time indices of the rheoencephalogram -TSFF (35.7%), cephalometric indices (21.4%), longitudinal, circumferential dimensions and diameters of the body (by 10.7%); to models of derivative indices of rheoencephalogram -TSFF (29.3%), the circumferential dimensions of the body and the width of distal epiphyses of long limb bones (17.1%) and body diameters (14.6%). цефалометричні показники, товщина шкіри і жирових