Научная статья на тему 'Peculiarities of psychological, clinical and instrumental indicators in children with vegetative dysfunction and hypotension under the influence of innovative psychocorrective program'

Peculiarities of psychological, clinical and instrumental indicators in children with vegetative dysfunction and hypotension under the influence of innovative psychocorrective program Текст научной статьи по специальности «Клиническая медицина»

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Ключевые слова
VEGETATIVE DYSFUNCTION WITH HYPOTENSION / INNOVATIVE PSYCHOCORRECTIVE PROGRAM WITH ELEMENTS OF MUSIC THERAPY VISUAL ART THERAPY AND GELOTOLOGY / CHILDREN / ВЕГЕТАТИВНА ДИСФУНКЦіЯ З ГіПОТЕНЗієЮ / іННОВАЦіЙНА ПСИХОКОРЕКЦіЙНА ПРОГРАМА З ЕЛЕМЕНТАМИ МУЗИКОТЕРАПії іЗОТЕРАПії ГЛОТОЛОГії / ДіТИ / ВЕГЕТАТИВНАЯ ДИСФУНКЦИЯ С ГИПОТЕНЗИЕЙ / ИННОВАЦИОННАЯ ПСИХОКОРРЕКЦИОННАЯ ПРОГРАММА С ЭЛЕМЕНТАМИ МУЗЫКОТЕРАПИИ ИЗОТЕРАПИИ ГЕЛОТОЛОГИИ / ДЕТИ

Аннотация научной статьи по клинической медицине, автор научной работы — Mitjurjajeva I.O., Kuhta N.M., Tarnavska O.V., Dolgopolova O.V.

Background. To study the features of psychological state, clinical and instrumental parameters in children with vegetative dysfunction (VD) and hypotension influenced by comprehensive treatment with the inclusion of the innovative psychocorrective program with elements of music therapy, visual art therapy and gelotology. Materials and methods. The study included 57 patients with VD and hypotension aged 12 to 17 years, 37 of them received psychotherapy with innovative program “Our drugs music, laughter, creativity” in comprehensive treatment, 20 children (control group) received basic treatment without psychological assistance. General clinical, laboratory, instrumental and psychodiagnostic studies were performed both in main and control groups. Results. Using innovative psychocorrective program in children with VD and hypotension as a part of comprehensive treatment contributed to the improvement of clinical and instrumental data: number of cases with autonomic influences on the heart reduced (from 22.1 to 5.25 %, р < 0.05), orthostatic test autonomic provision was normalized in 40.5 % of children, psychological state improvement was observed in 74.1 % of cases. Conclusions. Innovative psychocorrective program with elements of music therapy, visual art therapy and gelotology can be recommended as a part of comprehensive treatment of children with VD and hypotension in hospital environment and in future psychological support of patients.

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Текст научной работы на тему «Peculiarities of psychological, clinical and instrumental indicators in children with vegetative dysfunction and hypotension under the influence of innovative psychocorrective program»

ребенка

КлУчна пед1атр1я / Clinical Pediatrics

UDC 616.8-009.86:616.12-008.331.4-053.2-07-085.851+615.851

DOI: 10.22141/2224-0551.12.2.2017.99764

I.O. Mitjurjajeva, N.M. Kuhta, O.V. Tarnavska, O.V. Dolgopolova Bogomolets National Medical University, Kyiv, Ukraine

Peculiarities of psychological, clinical and instrumental indicators in children with vegetative dysfunction and hypotension under the influence of innovative psychocorrective program

For cite: Zdorov'ye Rebenka. 2017;12:109-16. doi: 10.22141/2224-0551.12.2.2017.99764

Abstract. Background. To study the features of psychological state, clinical and instrumental parameters in children with vegetative dysfunction (VD) and hypotension influenced by comprehensive treatment with the inclusion of the innovative psychocorrective program with elements of music therapy, visual art therapy and gelotology. Materials and methods. The study included 57 patients with VD and hypotension aged 12 to 17 years, 37 of them received psychotherapy with innovative program "Our drugs — music, laughter, creativity" in comprehensive treatment, 20 children (control group) received basic treatment without psychological assistance. General clinical, laboratory, instrumental and psychodiagnostic studies were performed both in main and control groups. Results. Using innovative psychocorrective program in children with VD and hypotension as a part of comprehensive treatment contributed to the improvement of clinical and instrumental data: number of cases with autonomic influences on the heart reduced (from 22.1 to 5.25 %, p < 0.05), orthostatic test autonomic provision was normalized in 40.5 % of children, psychological state improvement was observed in 74.1 % of cases. Conclusions. Innovative psychocorrective program with elements of music therapy, visual art therapy and gelotology can be recommended as a part of comprehensive treatment of children with VD and hypotension in hospital environment and in future psychological support of patients.

Keywords: vegetative dysfunction with hypotension; innovative psychocorrective program with elements of music therapy, visual art therapy and gelotology; children

Introduction

Vegetative dystonia (VD) with hypotension is one of the most common pathological conditions among all somatic pathology in adolescents, because of pubertal hormonal changes in the body, functional stress of various organs and systems and significant mental-physical activity. The disease is characterized by signs and symptoms of psychoemotional disorders, sensitive, motor and vegetative activity in children [10]. A communication is proven between hemodynamic parameters and level of anxiety in the genesis of VD with hypotension. Thus, high anxiety combined with hypersympatotonic auto-nomic reactivity and insufficient supply of autonomic

activity, which indicates high excitability and rapid depletion od the sympathoadrenal system. A representative of the theory of differential emotions K. Izard says that anxiety consists of the dominant emotion of fear and its interaction with one or more basic emotions: suffering, anger, guilt, shame and interest [6].

Psychological distress, tension, confusion, indeci-siveness, impotence in difficult situations, disorder of self-regulation processes, inadequate self-esteem and physiological responses (increased heart rate, pale skin, sweaty limbs) occur simultaneously and often lead to disease, because the information during perception of events the flow first to the thalamus, where the impulses

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© «Child's Health», 2017 © «Здоров'я дитини», 2017

© Publisher Zaslavsky O.Yu., 2017 © Видавець Заславський О.Ю., 2017

For correspondence: Inga Mitjurjajeva, MD, Professor at the Department of pediatrics N 4, Bogomolets National Medical University, T. Shevchenko boulevard, 13, Kyiv, 02000, Ukraine; e-mail: [email protected]

Для кореспонденци: Мгторясва 1нга Олександршна, доктор медичних наук, професор кафедри педетрп № 4, Нацюнальний медичний ушверситет ¡меш О.О. Богомольця, бульвар Тараса Шевченка, 13, м. Ки'Гв, 02000, УкраТна; e-mail: [email protected]

are divided: a part goes to the cerebral cortex, where the subjective sensation is formed, and another part to the hypothalamus, which is responsible for autonomic responses [6, 10].

It is known that children that have VD with hypotension are mostly characterized with personality traits such as vulnerability, insecurity and increased perception of stress. Each child problem develops because of some family problems, such as the possibility of parental divorce, the birth of a second child, etc. [6]. According to literature psychotherapeutic methods were used in the treatment of VD with hypotention: rational, group psychotherapy, autogenic training depending on gender, art therapy in the form of drawings. Given the state of the quality of life, stress in connection with a military threat to Ukraine, the psychological problems of adolescents that have VD with hypotension are a serious danger for the further development of the disease in adulthood. That is why the continued search of updated psychological approaches to help sick children, taking into account known facts of the impact of music on neuroendocrine function, particularly at the level of certain hormones in the blood that play a crucial role in the formation of emotional responses; isotherapy as a tool for research and harmonization of those aspects of the inner world of the child for which words don't reach, solving problems using humor [3, 5] is very important.

The purpose of the research was to study the dynamics of changes in the mental status, clinical and instrumental parameters in children with VD and hypotension influenced by complex treatment with the inclusion of the innovative psycho-program "Our drugs — music, laughter, creativity" with elements of music therapy, isotherapy and gelotology in the hospital.

Materials and methods

The study included 57 patients with VD and hypotension treated in the Center of autonomic dysfunction, Kyiv at the Child Clinical Hospital N 6. The age of patients ranged from 12 to 17 years old. Among them there were 45 girls and 12 boys. Patients were divided into two groups: main and control. Members of the main group (n = 37) received the standard basic treatment, which included the application of daily regime, diet, drug therapy, psycho-program "Our medicines — music, laughter, creativity", with elements of music therapy, isotherapy and gelotology. Participants in the control group (n = 20) received only basic treatment.

General clinical, laboratory and instrumental examinations were performed before and after treatment. Subjective and objective indicators were assesed, as well as and the results of the survey of autonomic homeostasis: via Wayne's adapted to child age tables the output of au-tonomic tone was estimated, orthostatic test was done by general procedure — autonomic sufficiency, status of the cardiovascular system — electrocardiography (ECG), cerebral blood flow — rheoencephalography (REG), brain activity using electroencephalography (EEG) [1, 2]. Blood preassure was determined with the single measurement method by standard triple test.

The assesment of the state of cerebral hemodyna-mics was performed by determining the status of REG arterial pulse blood filling, peripheral vascular resistance and condition of venous outflow, as well as the asymmetry coefficient. To analyze rheographic curves standard methods were used. The registration of REG curve was performed on electrocardiograph 6 NEK-4 with the help of 4-RG-2M 4 channel box at paper speed of 50 mm/ sec and the value of calibration signal at 0.1 Ohm for the described method.

State of the central nervous system activity was studied using EEG, which was performed on an eight-channel electroencephalograph "Schwazer-ED-14" (Germany). Registration of brain activity was carried out in a state of relaxed wakefulness. EEG recording was performed in a reclining position of the patient with eyes closed in dark conditions and silence. Previously the patients were subjected to 15-20-minute adjustment. Background acti-vi-ty and EEG were recorded during the functional test (in this case — hyperventilation). All subjects were subjected to mono and bipolar recording. Background activity was analyzed by the following parameters: frequency, amplitude and distinctiveness of high (a, p) and slow (8, 9) potencials, presence of focal and convulsive paroxysms. EEG into account age features. Age specifications of EEG were taken into account.

Echoencephalography was conducted on echoen-cephaloscope EPS-12 (Russia) with the transmission method of assessment of middle and displaced M-echo, as well as the presence of pulsation.

Electrocardiography (ECG) was used to characterize the condition of the cardiovascular system [1].

Before psychic correction treatment was carried out consultations with doctors about the status of each child were conducted and consent of children and their parents on such a form of treatment was obtained. Psychological testing was carried out on the terms of the Privacy Policy.

Psychodiagnosis was conducted before and after the psychocorrection treatment during standard basic therapy techniques used in child clinical psychology: rapid assessment of health, activity, mood (HAM) [8], Goldberg, Benjamin and Creed's screening tests using A (alarm) and D (depression) scales [4], the Olshan-nikov — Rabinovich method, which determines a person's tendency to experience the three basic emotions (fear, anger, joy) [7].

To normalize the emotional state, ensuring the remedial impact in three areas: communication (doctor and psychologist establish contact with patient, interpersonal contacts in the group), regulatory (removal of the neu-ropsychological stress), reactive (to achieve catharsis, purification of pathological states) we have created an innovative psychocorrective program with elements of music therapy, isotherapy and gelotology "Our drugs are music, laughter, creativity". The program used the principles of positive psychotherapy that allows to understand that there are problems and difficulties, and, at the same time, that there are resources and possibilities. To maximize the therapeutic potential of correction

the treatment was conducted in small groups of 10—12 children. The duration of one session was 40—50 minutes; the course was designed to last for 12—14 sessions 5 times a week in heterogeneous by gender, age, personality styles and conflict groups.

Training sessions in which the focus was on psychological problems more characteristic in children with VD and hypotension, on topics "How to overcome fear?", "Conflict is not a problem, but an opportunity", "Excellently self-esteem", "Ways out of stress", "Laughter treatment" consisted of mini-lectures, group discussions, brainstorming — the method of group discussion of the problem with the aim of solving it, structured exercises that have enabled each participant to learn from their own experience different feelings, movement exercises that activate attention, increase the level of activity and trust in the participants, thematic drawing, role-playing situations etc. The technical work contained receptive music therapy based on passive perception of music, isotherapy, given that symbolic language of pictures are most adequate to express the unconscious; classic direction of gelotology (using anecdotes, humorous stories, etc.).

Statistical analysis was performed using mathematical software package Stata 12.0 (licensed European version).

Results and discussion

Almost all patients in the main and control group complained of headaches (90.2 and 92.1 % respectively); heartache (40.5 and 37.2 %); dizziness (70.4 and 72.1 %); sleep disorder (10.4 and 8.1 %); emotional lability (50.3 and 49.1 %); weakness (35.5 and 30.6 %). After treatment the majority of the patients of the main group

noted a decrease in the intensity of headaches (68.4 %), heartaches (29.7 %), dizziness (50.8 %), emotional lability (48.6 %), improvement of night sleep (8.5 %), increase of functional abilities (32.3 %).

The control group showed a possitive trend on patient complains 3 times lower than in the main group.

We reaserched the medical history of the patients with VD and hypotension, which showed that the disease was the result of constant stress (60.4 %), anxiety (87.2 %), significant difficulty adapting to school life (48.5 %), out of school: complains from elders (30.4 %), isolation (62.1 %), tense situation in the relations with peers (68.5 %), etc. In conversations teenagers usually noted low satisfaction with the situation (52.3 %), constant search for the meaning in life, which is due to the dificulties of growing up (20.4 %). Our observations suggest that, in this sence, the most vulnerable are teenagers who are not in a very friendly relationship with their own parents (62.6 % of the subjects).

Research by the method of rapid assessment of health, activity, mood (HAM) to provide for children features emotional state before and after the psycho programs. The research results are presented in table 1.

Analyzing the initial results with the HAM method we diagnosed malaise in 73 % (27 patients) of the main group and in 75 % (15 patients) in the control group, low activity in 54 % (20 patients) and 55 % (11 patients), respectively, bad mood in 43.2 % (16 patients) and 60 % (12 patients). Repeated tests showed a positive trend change in the main group. So, has significantly improved in 21 patients (56.8 %) of the main group and in 4 patients (20 %) in the control group. Activity was significantly increased by 43.2 % (16 patients) in the study group and 15 % (3 patients)

Table 1. The results of psychological testing using the HAM method before and after providing psychological care to patients with VD and hypotension

Parameters Number of patients, n (%)

Main group (n = 37) Соntrol group (n = 20)

Before treatment After treatment Before treatment After treatment

Health state

Low 27 (73)* 6 (16.2) 15 (75) 11 (55)

Average 8 (21.6) 16 (43.2) 5 (25) 8 (40)

Normal 2 (5.4) 15 (40.6)* 0 1 (5)

Activity

Low 20 (54)** 4 (10.8) 11 (55) 8 (40)

Average 12 (32.4) 20 (54) 7 (35) 7 (35)

Normal 5 (13.6)* 13 (35.2) 3 (15) 5 (25)

Mood

Low 16 (43.2) 2 (5.4) 12 (60) 8 (40)

Average 16 (43.2) 20 (54) 7 (35) 9 (45)

Normal 5 (13.6) 15 (40.6) 1 (5) 3 (15)

р* 0.73 0.76

Notes: * — p < 0.05 — reliability of differences on the criterion X (xi-square); ** — р < 0.01.

Table 2. Results of the study of patients with VD and hypotention before and after the psychocorrective actions (using the Goldberg — Benjamin — Creed method)

Number of participants Parameters, n (%)

Anxiaty Depression

Before treatment After treatment Before treament After treatment

Main group (n = 37) 32 (86.5) 13 (35.1)* 12 (32.4) 2 (5.5)*

Control group (n = 20) 19 (95) 17 (85) 7 (35) 6 (30)

Note: * — p < 0.05 — reliability of differences on the criterion X (xi-square).

in the control group. Mood improved in 37.7 % (14 patients) of the main group and 20 % (4 patients) in the control group.

Results of study using D. Goldberg, S. Benjamin, F. Creed screening tests on two short A (alarm) and D (depression) scales are presented in table 2.

Using the Benjamin — Goldberg — Creed screening method it was shown that there is a high level of anxiety in 86.5 % (32 patients) the main group and 95 % (19 patients) in the control group, conditions with episodes of depression in 32.4 % (12 patients) in the main group and 35 % (7 patients) in the control group. After treatment, tests showed a significant decrease in anxiety by 51.4 % (19 patients) in the main group and 10 % (2 patients) in the control group, conditions with episodes of depression were significantly decreased by 26.9 % (10 patients) in the main group only 5 % (1 patient) in the control group.

Research by Olshannykov — Rabinovich method let's us determine the susceptibility of children to the experience of the three basal emotions: fear, anger, joy. Table 3 presents the results of the research.

By the Olshannikov — Rabinovich method high fear level were found in 81.1 % (30 patients), of the main group and in 80 % (16 patients) of the control

Table 3. Results of the study patients VD and hypotention using the Olshannikov — Rabinovich method before

and after psychocorrective actions

Parameters Number of patients, n (%)

Main group (n = 37) Control group (n = 20)

Before treatment After treatment Before treatmnet After treatment

Fear

High 30 (81.1) 1 (2.7)* 16 (80) 16 (80)

Average 3 (8.2) 20 (54.1)* 4 (20) 3 (15)

Low 4 (10.8) 16 (43.3) 0 1 (5)

Anger

High 25 (67.5) 0* 13 (65) 11 (55)

Average 10 (27.1) 30 (81)* 4 (20) 6 (30)

Low 2 (5.4) 7 (19)* 3 (15) 3 (15)

Joy

High 18 (48.7) 27 (72.9) 10 (50) 11 (55)

Average 7 (18.9) 10 (27.1) 5 (25) 4 (20)

Low 12 (32.4) 0* 5 (25) 5 (25)

р* 0.04 0.81

Note: * — p < 0.05 — reliability of differences on the X2-criteria (xi-square).

120 n

100 -

100

80 "

81.1

60 -

40

50

40

45 45

20 "

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13.4

5.4

10

10

Before After Before After

treatment treatment treatment treatment Main group Control group

■ Sympatic tone

■ Eutone □ Vagotone

Figure 1

group, high level of anger in 67.5 % (25 patients) in the main group and in 65 % (13 patients) in the control group; low levels of joy were observed in 32.4 % (12 patients) and 25 % (5 patients), respectively. Repeated testing after treatment showed a tendency to decrease fear by 78.3 % (29 patients) anger by 67.5 % (25 patients), increase in joy by 51.4 % (19 patients) in the main group. In the control group a decrease in anger by 10 % (2 patients) was observed, indicators of fear and mood remained the same.

Given the initial results of the three methods (high anxiety, elements of depression, poor health, low activity, low mood, high levels of fear, anger, low levels of joy) and referring to the analysis of possible strategies for treatment, on our training sessions we focused on developing skills for fighting childhood fears, conflicts through play, drawing, humor.

At the beggining of the sessions 18.7 % of adolescents easily joined in and were willing to talk about themselves and their situation, 58.2 % listened with interest but said little, 10.5 % showed complete indifference to the sessions.

Drawing while listening to music helped all children to "open up". In the drawings the children reflected what is going on in their lives now what they have experienced and what can not be forgotten. Teens interpretred their feelings in pictures: "My parents neglect me", "Parents don't value my time", feelings which can be clearly seen on the pictures of patient M., 15 years old, and patient D., 13 years old, before treatment (figures 2, 4). The pictures and statements of these adolescents following treatment showed a change in their attitude to the problems of hopelessness to finding a solution (figure 3 "Kindness is blind and sincere" and figure 5 "A world where all are singing and dancing"), in which creativity, originality and critical thinking were observed.

A check the performance of our established programs was carried out during the psychotherapeutic process through feedback and after its completion. Attention was focused on the overall health of adolescents, their attitude to the group process, expression of feelings in the process of listening to music.

Teens stated that the music helped them "get to know themselves", ie to assess their strengths and weaknesses

Figure 2. "Solitude" drawn by patient M., 15 years old, diagnosed with VD and hypotension, before treatment

Figure 3. "Kindness is blind and sincere" patient M., 15 years old, with VD and hypotension after treatment

Figure 4. "Life under pressure" patient D., 13 years old, with VD and hypotension before treatment

Figure 5. "A world where all are singing and dancing" patient D., 13 years old, with VD and hypotension after treatment

to be able to solve their own problems, to get over anxiaty and get rid of it.

Music therapy treatment results of adolescents with VD and hypotention are shown in table 4.

Negative results were found in none of the patients. The most positive results were achieved with the help of fantasy and developed imagination while listening to J. Iglesias "Life goes on the same" in 94.6 %, in 89.2 % when listening to Beethoven's Overture "Edmond" and 81.08 % when listening Mozart's Turkish waltz "Rondo", developed the ability to see, listen and hear themselves and others. Suite "Morning" from the works of "Peer Gynt" E. Grieg at in case of 86.4 % of patients, "Ode to Joy" by L. Beethoven allowed 78.4 % patients to feel stronger, more confident, able to make consious choices for their own health.

A survey of the children and their parents showed that working in the group allowed anxious adolescents to increase their self-esteem (40.2 %), contributed to the development of effective interaction skills, with parents included.

According to the objective clinical and instrumental examinations the blood pressure in both experimental groups using one-time measurement method on average before treatmentregarding age norms ranged from: systolic blood pressure = 101.8 ± 8.7, diastolic blood pressure = 63.6 ± 4.8. After treatment the main group showed a steady increase of blood pressure: systolic — statistically significant (p = 0.02), an average of 106.00 ± 7.26 and diastolic (p = 0.66) to 61.10 ± 5.18. The control group had no significant changes in BP.

The evaluation of the functional state of autonom-ic homeostasis before and after complex therapy with

provided psychological assistance was carried out on the basis of its main components - autonomic tone and provision.

Analysis of patient examination data using Wayne tables of the main group showed that 5.6 % of patients appeared to have sympatikinetic direction of initial ANS tonusin 11.1 % — parasympathicotonic in euto-nia 81.1 % was observed (table 5). Similar data was also studied in the control group: sympatoconic — at 13.3 %, parasympathicotonic — 40 % eutonic in 66.7 % after treatment. In 100 % of children in main group eutonic direction of ascending tone BHC was observed — 40 %, while the control group had the eutonic direction even decreased by 5 %.

According to the orthostatic test, normal autonom-ic sufficiency during the first examination was observed in only 18.9 % of the main group, insufficient levels in 52.7 %, excess levels in 27.9 %. In the control group insufficient levels of autonomic sufficiency were noted in 50 % — excess in 15 %, sufficient levels in 35 %. After a complex, including psychological methods, treatment a 22.2 % increase in the number of children with sufficient autonomic sufficiency (p < 0.05), and an increase of 5 % was noted in the control group (p < 0.05). After treatment, the normal reaction to orthostatic test was in 40.5 % of children (p < 0.05). In the control group a normal reaction to orthostatic test before and after treatment was 35 and 40 % (p < 0.05), respectively (table 6).

An analysis of ECG data in children with hypo-tensive type of VD, who received complex medication and psychological treatment, showed a statistically significant reduction in the incidence of autonomic influences on the heart (from 22 to 5 %, p < 0.05). It

Table 4. Results of music therapy treatment in adolescents with VD and hypotention

№ Name of music composition Number of patients with VD and hypotension (n = 37), n (%)

Positive results Indifferent

1 Mozart turkish waltz, "Rondo" 30 (81.08)* 7 (18.92)

2 Grig, "Morning mood", act four of the "Peer Gynt" Suite 32 (86.4)* 5 (14.6)

3 Beethoven, "Ode to joy" 29 (78.4)* 8 (21.6)

4 J. Iglesias, "Life goes on the same" 35 (94.6)* 2 (5.4)

5 Beethoven, Ouverture "Egmont" 33 (89.2)* 4 (10.8)

Autonomic tone Number of patients, n (%)

Main group (n = 37) Control group (n = 20)

Before treatment After treatment Before treatment After treatment

Sympatic tone 2 (5.4) 0* 2 (10) 2 (10)

Eutone 30 (81.1) 37 (100) 10 (50) 9 (45)

Vagotone 5 (13.5) 0* 8 (40) 9 (45)

p* 0.025 0.94

Note: * — p < 0.05 — reliability of differences on the x2-criteria (xi-square).

Note: * — p < 0.05 — reliability of differences on the x2-criteria (xi-square). Table 5. Ascending initial autonomic tonus in children with VD and hypotension before and after treatment

Table 6. Orthostatic test indicators in children with VD with hypotension before and after the treatment

Parameter Number of patients, n (%)

Main group (n = 37) Control group (n = 20)

Before treatment After treatment Before treatment After treatmentn

Hypersympatotonic 3 (8.2) 3 (8.2) 0 0

Astenosympatic 6 (16.2) 8 (21.6) 2 (10) 1 (5)

Hyperdyastolic 2 (5.4) 6 (16.2) 0 0

Asympatotonic 17 (45.9) 5 (13.5) 10 (50) 10 (50)

Sympatoastenic 2 (5.4) 0 1 (5) 1 (5)

Normal 7 (18.9) 15 (40.5)* 7 (35) 8 (40)

р* 0.034 0.94

Note: * — p < 0.05 — reliability of differences on the %2-criteria (xi-square).

should be noted that in the control group, the figure rose from 20 to 35 %. The frequency of arrhythmia episodes in the main group decreased by 1.2 times, while in the control group it even increased from 15 to 45 % (p < 0.05). The group of children who received combined treatment had decreased incidence of metabolic changes by 5.6 %, and in the control group the the parameter remained unchanged.

Analysis of changes in EEG and EchoEG during treatment in patients of the main group demonstrated a reduction of bioelectrical activity of brain nature by 2.1 times, phenomenon of cortical irradiation — by 1.8 times, a marked stimulation of median brain structures — by 2.3 times and reduce pulsation of m-echo by 6.1 times. In the control group, statistically significant changes were not observed.

REG showed that children with VD when adding complex treatment the frequency of blood supplying disorders in the area of internal carotid artery decreased by 16.3 % (from 51.4 to 35.1 %), while in the control group no significant changes were found. Venous outflow significantly improved in the main group. Thus, the frequency of types with complications decreased by 25 % (from 62.2 to 37.8 %) compared to the same period in the control group, which only improved by 10 % (from 90 to 80 %).

An analysis of psychological testing, clinical and instrumental examination, feedback confirmed the efficiency of psycho innovative program with elements of music therapy, isotherapy, gelotology in complex treatment of children with VD and hypotension.

Research carried out by approved medical and psychological principles of ethics. Side effects were not found in all case.

Conclusions

1. Incorrect life balance (60.4 % strain, fatigue 48.5 %), unfriendly relations with parents — 62.6 %, psychological trauma — 62.1 %, scares — 30.4 %, 87.2 % of unrest lead to anxiety, displayed in emotional, behavioral and cognitive spheres of personality and are precipitating and supporting factors of VD with hypotension in children.

2. Comparison of the results of psychological tests before and after treatment using a complex psycho innovation program "Our medicines — music, laughter, creativity" in comparison with patients who did not receive it, showed effective normalization and psychological state of children suffering from hypotension with VD: an certain improvement in health by 56.8 %, activity by 43.2, mood by 37.7 % in the main group and by 20, 15, 20 % in the control group respectively; reduced anxiety was noted 51.4 %, states with elements of depression by 26.9 % in the main group (in the control group — by 10 and 5 % respectively); decrease by 78.3 % of fear, anger by 67.5 %, increased joy index in 51.4 % of the main group (the control group marked a decrease of anger in only 10 %, figures of fear and mood remained at the same level).

3. Used in the innovative psycho-nondirective program with an indirect approach allowed children with VD and hypotension showed creativity, and using self — regulation to get rid of psychosomatic symptoms, adapt to various difficult situations: music contributed to the emotional saturation; while drawing children adequately expressed and understood psychological problems; through humor negative emotions and feelings were let out.

4. The results of clinical and instrumental methods after complex treatment a normal reaction to orthostatic test was noted in 40.5 %, ECG analysis in children ofthe main group showed a statistically significant reduction in cases of autonomic influences on the heart (from 22.1 to 5.25 %, p < 0.05), in terms of REG it was found that the frequency of violations of blood supply in the area of internal carotid artery decreased by 16.3 % (from 51.4 to 35.1 %), while in the control group no significant changes were identified .

5. Studies indicate that innovative psycho program "Our drugs — music, laughter, creativity", with elements of music therapy, isotherapy, gelotology justify its widespread use as an effective component in the treatment of children with hypotensive type of VD in hospitals.

Conflicts of interests. Authors declare the absence of any conflicts of interests that might be construed to influence the results or interpretation of their manuscript.

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OTpuMaHO 21.03.2017 ■

Мкюряева 1.О., Кухта Н.М., Тарнавська О.В., Долгополова О.В. Нацюнальний медичний у^верситет iM. О.О. Богомольця, м. Кив, Укра'на

Особливост психолопчного стану та клшкоЧнструментальних показниюв у д^ей, хворих на вегетативну дистоыю з ппотенз^ю, тд впливом шноващйноТ психокорекцшноТ програми

Резюме. Мета: вивчити особливост психолопчного стану та клшко-шструментальних показнишв у дггей, хворих на вегетативну дистошю (ВД) iз гiпотензieю, тд дieю шновацшно1 психокорекцшно1 програми з елементами музикотерапи, iзотераmi, глотологи. Матерiали та методи. Обстежено 57 хворих дггей вшом 12—17 ротв, 37 з яких отримували психотерапевтичне лжування за шновацш-ною програмою «Наш1 лiки — музика, смiх, творч1сть» у складi комплексного л^вання, 20 дггей (контрольна трупа) отримували базовий комплекс л^вання без надання психологiчноi допомоги. Проведеш загальноклшчне, лабораторно-шструментальне та психодiагностичне до-слщження до та тсля лшування в основнш та контроль-шй групах. Результата. Використання в комплексному

лшуванш дггей, хворих на ВД i3 гiпотензieю, iнновацiйноï психокорекцiйноï програми сприяло покращанню клшь ко-iнструментальних даних: зниженню випадыв вегета-тивних впливiв на серце (з 22,1 до 5,25 %, р < 0,05), нор-малiзацiï вегетативного забезпечення клiноортостатичноï проби в 40,5 % дтей, покращанню психологiчного стану в 74,1 % випадыв. Висновки. Iнновацiйна психокорекцшна програма з елементами музикотерапи, iзотерапiï, глотоло-riï може бути рекомендована в складi комплексного лщу-вання дiтей i3 ВД та riпотензieю в умовах стацiонару та в подальшому психологiчному веденнi пацieнтiв. K™40BÎ слова: вегетативна дисфункц1я з гiпотензieю; iнновацiйна психокорекцiйна програма з елементами музикотерапи, iзотерапiï, глотологи; дни

Митюряева И.А., Кухта Н.Н., Тарнавская Е.В., Долгополова О.В.

Национальный медицинский университет имени А.А. Богомольца, г. Киев, Украина

Особенности психологического состояния и клинико-инструментальных показателей у детей, больных вегетативной дистонией с гипотензией, под влиянием инновационной психокоррекционной программы

Резюме. Цель: изучить особенности психологического состояния и клинико-инструментальных показателей у детей, больных вегетативной дистонией (ВД) с гипотен-зией, под воздействием инновационной психокоррекци-онной программы с элементами музыкотерапии, изотера-пии, гелотологии. Материалы и методы. Обследовано 57 больных детей в возрасте 12—17 лет, 37 из которых получали психотерапевтическое лечение по инновационной программе «Наши лекарства — музыка, смех, творчество» в составе комплексного лечения, 20 детей (контрольная группа) получали базовый комплекс лечения без предоставления психологической помощи. Проведены общеклиническое, лабораторно-инструментальное и психодиагностическое исследования до и после лечения в основной и контрольной группах. Результаты. Использование в комплексном лечении детей, больных ВД с гипотензией,

инновационной психокоррекционной программы способствовало улучшению клинико-инструментальных данных: снижению случаев вегетативных влияний на сердце (с 22,1 до 5,25 %, р < 0,05), нормализации вегетативного обеспечения клиноортостатической пробы у 40,5 % детей, улучшению психологического состояния в 74,1 % случаев. Выводы. Инновационная психокоррекционная программа с элементами музыкотерапии, изотерапии, гелотоло-гии может быть рекомендована в составе комплексного лечения детей с ВД и гипотензией в условиях стационара и в дальнейшем психологическом сопровождении пациентов.

Ключевые слова: вегетативная дисфункция с гипотензией; инновационная психокоррекционная программа с элементами музыкотерапии, изотерапии, гелотологии; дети

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