Научная статья на тему 'Numerical simulation for magnetic nanoparticles drug delivery with laser photothermal therapy'

Numerical simulation for magnetic nanoparticles drug delivery with laser photothermal therapy Текст научной статьи по специальности «Медицинские технологии»

CC BY
61
18
i Надоели баннеры? Вы всегда можете отключить рекламу.
Ключевые слова
Magnetic nanoparticles / magnetic targeting delivery system / magnetic field / laser heating / computational modeling.
i Надоели баннеры? Вы всегда можете отключить рекламу.
iНе можете найти то, что вам нужно? Попробуйте сервис подбора литературы.
i Надоели баннеры? Вы всегда можете отключить рекламу.

Текст научной работы на тему «Numerical simulation for magnetic nanoparticles drug delivery with laser photothermal therapy»

B-PS-10

Numerical simulation for magnetic nanoparticles drug delivery with laser photothermal therapy

S. Salem1

1Saratov state university, physics faculty, Саратов, Russian Federation

This work will discuss about principle of magnetic targeting, mechanism of magnetic targeted drug delivery, magnetic nanoparticles in targeted drug delivery in the presence of magnetic field. Magnetically targeted drug delivery by particulate carriers is an efficient method of delivering drugs to localized disease sites such as tumours. High concentrations of chemotherapeutic or radiological agents can be achieved near the target site without any toxic effects to normal surrounding tissue. The magnetic nanoparticles as drug carriers provide huge opportunities in cancer treatment. The use of such carriers in targeted therapy considerably reduces the side effects of conventional chemotherapy. The magnetic drug targeting enables the fast and precise location of drug in the body with the use of external magnetic field.

Also using laser beam for destructive and killing the tumor cells and this occurs by increasing the temperature of tumor cells. This therapy used laser beam which illuminates through cells and generates temperature helping to destroy the tumor cells. In the present study, combination between laser irradiation together with a magnet (which help the magnetic nanopartical directed toward the target (tumor), and by using the laser beam which the source for energy the tumor damaged and destroyed. The equation of motion describing the problem was solved numerically. Description for the model given by Figure 1.

Fig. 1.

Keywords: Magnetic nanoparticles, magnetic targeting delivery system, magnetic field, laser heating, computational modeling.

i Надоели баннеры? Вы всегда можете отключить рекламу.