Сборник научных тезисов и статей "Здоровье и образование в XXIВеке" №2, 2010г. (Т.12)
NONCOMMUNICABLE DISEASES: THE TSIM TSOUM CONCEPT.
R.B. Singh, Agnieska Wilzynsca, Fabien De Meester, Wilson D.W., Hungin A.P.S.
Tsim Tsoum Institute, Krakow, Poland; Durham University, Durham, UK
The last few decades of the last century greatly increased our knowledge about the global dimensions of the noncommunicable diseases (NCD) including cardiovascular diseases (CVDs). Recent studies indicate that there is coexistence of nutritional deficiencies and appreciable overnutrition in the form of central obesity and overweight in developing countries and in developed countries one quarter of the population is obese. The Global Burden of Disease Study clearly showed that the gratifying gains in cardiovascular health occurred in developed countries, in association with an epidemic of CVD in the developing world. We proposed that overweight comes first in conjunction with inflammation, hyperinsulinemia, increased angiotensin activity, vascular variability disorders and central obesity followed by glucose intolerance, type 2 diabetes, hypertension, low HDL and hypertriglyceridemia (Metabolic syndrome).This sequence is followed by CAD, gall stones and cancers and finally dental caries, gastrointestinal diseases, bone and joint diseases, degenerative diseases of the brain and psychological disorders, during transition from poverty to affluence. As people become rich, they begin to increase their intake of proinflammatory refined foods; dietary fat, salt and sugar intake in the form of ready prepared foods, syrups, dairy products and flesh foods in place of grain based diet. There is a greater use of automobiles, television vewing and decrease in sports, walking and dancing as recreation which also enhances the inflammation, dyslipidemia and obesity. These changes in the diet and lifestyle in conjunction with mental strain, and increase in tobacco and alcohol intake, appear to be primary risk factors in the pathogenesis of inflammation and dyslipidemia leading to NCDs.
Correspondence: Dr RB Singh,MD President, Tsim Tsoum Institute, Ul.Golebia 2, 31-007, Krakow,Poland Email [email protected] tel in India:0591 2417437
Материалы1 XI международного конгресса «Здоровье и образование в XXI веке» РУДН, Москва, 2010
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