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abstracts. phytopharm 2012
addition of marjoram powder at level of 4 g/kg seemed to mune responses, and could be considered as a natural have a positive influence on growth performance and im- potential growth promoter for broiler chicks.
COMPARISON OF THE EFFECTS OF THYME
AND OREGANO ON HEMATOLOGY IN LAYING JAPANESE QUAIL
© Aghdam Shahryar Habib, Ebrahimnezhad Yahya, Gholipoor Vahid
Department of Animal Science, Shabstar branch, Islamic Azad University, Shabstar, Iran, Email: ha_shahryar@yahoo. com
The aim of this study was to compare effects of oregano (Mentha pulegiym), thyme (Thymus) on immune system in laying Japanese quail. 420 quails were feed in completely random design by 7 treatments and 4 replications (every replication involves 12 female and 3 male quails) by following ration for 45 days: 1) control diet (without thyme and oregano), 2)control diet+thyme 1.5 %, 3)control diet+thyme 3 %, 4)con-trol diet+thyme 4.5 %, 5)control diet+oregano 1.5 %, 6)control diet+oregano 3 %, 7)control diet+oregano 4.5 %. At the end of the experiment, 2 birds were selected from each replication and the hematology measures were analyzed. The result showed that us-
ing different levels of oregano and thyme in quail diet were affected on hematology. Monocytes had the highest consumer 4.5 % oregano than control group (9.25 vs 6.5 %). Adding oregano until 4.5 % had significant effect on basophile, oezinophil and monocyte. intake level of 4.5 % thyme observed highest level in basophile and oezinophil between groups (2.22 and 5.75 respectively). Containing 4.5 % oregano in group, suggests that differences in antioxidant and antioxi-dation properties, thyme and oregano. in conclusion, add thyme and oregano to the 4.5 % of the diet has significantly positive effect on the percentage of ba-sophile, oezinophil and monocytes.
MULTI-BIOACTIVE METABOLITES FROM RUDBECKIA HIRTA L. FLOWERS
© AhmedAtallah F.-12, Michael Botros R.2, Gedara Sahar R.2, Amer M. M.2, Stevenson Lesley3
Department of Pharmacognosy, College of Pharmacy, King Saud University, P. O. Box 2457, Riyadh 11451, Kingdom of Saudi Arabia
2Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Egyp
3Centre for Phytochemistry and Pharmacology, Southern Cross University, PO Box 157, Lismore NSW 2480, Australia
Black-eyed Susan or Rudbeckia hirta L. (Asteraceae) is a popular garden biennial herb. American indian used the root tea to treat worms and colds, and as a wash for sores and snakebites, while the root juice has been used to treat earache (1). The immunomodulatory organic extract of R. hirta flower heads was partitioned and subjected fractionation using a series of chromatographic techniques which led to the isolation of a new highly oxygenated pseudoguaianolide: (1S*,4S*,5R*,6R*, 7S*, 10S*,11S*)-4,14,15-tri-acetoxy-pseudoguaian-12-,6-olide along with three phenolic acids: P-resorcylic acid, (E)-p-coumaric acid, and (E)-caffeic acid; two phenolic esters: 3-O- (E)-caffeoylquinic acid and 3-O-(E)-coumaroylquinic acid methyl ester; a phenolic acid ether (Z)-p-coumaric acid-4-O-P-D-glucopyranoside;
two flavonol glycosides: gossypitrin and quercetagitrin; three methylated flavonol glycosides: eupatolin, patu-litrin, eupatolitin-3-O-P-D-glucopyranoside; and eu-patolitin-3-methyl ether. The structure of the new ses-quiterpene lactone 1 was established on the basis of extensive spectroscopic analyses, including 1D and 2D NMR. Most of isolated compounds exhibited antioxidant (oxygen radical absorbance capacity, ORAC), immunomodulatory, 5-lipoxygenase (5-LOX) inhibitory and cytotoxic activities at variable concentrations, which can be considered as a partial scientific evidence for the ethnopharmacological uses of the plant.
Reference: Barker, J. (2004) "The Encycol-pedia of North American Wild Flowers". Parragon Publishing Ltd. Bath, UK.
TOM 10/2012/2 Obzory po kliniceskoj farmacologii i lekarstvennoj terapii [Reviews of clinical pharmacology and drug therapy] I ^^ 33
