CC BY
2DOI 10.24412/cl-37136-2023-1-153-153
INSTRUMENT DEVELOPMENT AND APPLICATIONS OF LASER SPECTROSCOPY/MASS
SPECTROMETRY
YIXIANG DUAN1, QINGYU LIN1, WENWEN LI1 AND ZHONGJUN ZHAO1
1School of Mechanical Engineering, Sichuan University, China yduan@scu.edu.cn
ABSTRACT
At present, cancer seriously hampering the increasing life expectancy, developing an instant instrument and method has become an urgent objective. We developed a series of analytical instruments and further use them to recognition of tumor cells or early diagnosis of lunger cancer. We further focused on the analysis of tumor cells and tissue with Laser-induced breakdown spectroscopy. LIBS instrument and method can be used as the diagnostic analysis of clinical lung cancer tissues based on label-free imaging. The tumor cell can be also recognized by the corresponding aptamer sequence and can be detected by this SERS method. We proposed a novel PTR-TOF-MS instrument and developed a novel diagnostic method based on the detection of expired gas.
Figure: Diagnostic lung cancer with the PTR-TOFMS instrument.
