6в кн. - ISBN 978-5-238-01325-1; [Электронный ресурс]. - URL: http://biblioclub.ru/index.php?page=book&id=114719
3. Шапкин, А.С. Задачи с решениями по высшей математике, теории вероятностей, математической статистике, математическому
программированию: учебное пособие / А.С. Шапкин, В.А. Шапкин. - 8-е изд. -М.: Издательско-торговая корпорация «Дашков и К°», 2017. - 432 с.: табл., граф. - (Учебные издания для бакалавров). - ISBN 978-5-394-01943-2; [Электронный ресурс]. - URL: http://biblioclub.ru/index.php?page=book&id=450779
УДК 615.099-056.2
Корнилова Анастасия Игоревна Kornilova Anastasia Igorevna
Студент магистратуры Master's degree student Санкт-Петербургский государственный университет
Saint Petersburg State University
ВЛИЯНИЕ РТУТИ НА РАЗВИТИЕ ЗАБОЛЕВАНИЙ СЕРДЕЧНО-СОСУДИСТОЙ СИСТЕМЫ У ЖЕНЩИН ГОРОДА ЧЕРЕПОВЦА ВОЛОГОДСКОЙ ОБЛАСТИ
INFLUENCE OF MERCURY ON THE DEVELOPMENT OF CARDIOVASCULAR DISEASES IN WOMEN OF THE CITY OF CHEREPOVETS, VOLOGDA REGION
Аннотация: Работа посвящена изучению влияния ртути на риск развития заболеваний сердечно-сосудистой системы у женщин. В исследовании приняли участие 895 женщин города Череповца. Результаты показали, что высокие концентрации ртути могут привести к увеличению риска развития сердечно-сосудистых заболеваний.
VII Международная научно-практическая конференция
Abstract. The work is devoted to the study of the effect of mercury on the risk of developing diseases of the cardiovascular system in women. The study involved 895 women from the city of Cherepovets. The results showed that high concentrations of mercury can lead to an increased risk of cardiovascular disease.
Ключевые слова, ртуть, токсичные элементы, тяжелые металлы, сердечно-сосудистые заболевания, артериальное давление, волосы, женщины.
Key words: mercury, toxic elements, heavy metals, cardiovascular diseases, blood pressure, hair, women.
Mercury (Hg) is a toxic chemical element and a heavy metal contained in water, air and soil. Mercury compounds have long been known as toxic substances for all living organisms. Currently, a person can be exposed to the negative effects of mercury from several different sources: eating contaminated fish and seafood, using creams and disinfectant solutions, using amalgam fillings in dentistry and working in the industry of fluorescent lamps [1, p. 128; 2, p. 360]. The World Health Organization considers mercury as one of the 10 main groups of chemicals that pose a significant public health problem [3]. In humans, when poisoning with mercury and its compounds, pathological changes occur on the part of the cardiovascular, nervous, respiratory and other systems of the body [3]. The US National Research Council concluded that mercury exposure has implications for cardiovascular disease, as the toxic effects of methylmercury include increased blood pressure, and noting that abnormal heartbeats, abnormal electrocardiogram and myocarditis have been reported in cases of mercury poisoning [4, p. 357].
The aim of the study is to study the effect of mercury on the development of cardiovascular diseases in women in the city of Cherepovets.
The study involved 895 women aged 18 to 89 years. The collection of material was carried out in medical institutions in the city of Cherepovets. The questionnaire data contained information about blood pressure indicators. Hair samples were taken in the form of a bundle. The mercury concentration in the samples was determined using a mercury analyzer RA-915M. Statistical data processing was performed in the STATISTICA program.
VII Международная научно-практическая конференция The average mercury content in the hair of women living in Cherepovets was 0,494 ± 0,019 mg/kg (Table 1).
Table 1. Mercury content indicators for the entire sample of
women in Cherepovets
Indicator N Mean Median Min Max SD SE
Mercury concentration, mg/kg 895 0,494 0,343 0,0006 5,959 0,579 0,019
Note. N - sample, Mean - arithmetic mean, Min - minimum value, Max - maximum value, SD - standard deviation, SE - mean error
The average values of women's blood pressure are 122 and 76 mm Hg and correspond to the reference values, but the minimum and maximum values of systolic (SBP) and diastolic (DBP) blood pressure levels exceed the reference range (Table 2).
Table 2. Characteristics of the indicators of SBP and DBP in the patients of Cherepovets
Indicators N Mean Median Min Max SD SE Reference values [5, p. 2010]
SBP, mm Hg 895 122,451 120,000 90,000 194,000 19,050 0,635 100-135
DBP, mm Hg 895 76,372 75,000 58,000 111,000 11,027 0,368 65-85
Note. N - sample, Mean - arithmetic mean, Min - minimum value, Max - maximum value, SD - standard deviation, SE - mean error
When determining the correlation dependencies, a positive relationship was found between the concentration of mercury in the hair and the values of SBP (Fig. 1) and DBP (Fig. 2), at p < 0,05.
г = 0Л47; р < 0,05
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Figure 2. Positive correlation between mercury concentration and DBP values
The results of an earlier study revealed a significant positive relationship between the concentration of mercury in the hair and arterial hypertension, as well as between the concentration of mercury and systolic and diastolic blood pressure [6, p.
VII Международная научно-практическая конференция 076002-9]. Other studies have also found the effect of mercury exposure on the increase in blood pressure in the examined patients [7, p. 625; 8, p. 2245].
An increase in evidence suggests that exposure to mercury may lead to an increased risk of adverse cardiovascular effects in a population that has been exposed to this form of metal.
Reference list:
1. Mahaffey K.R. Mercury exposure: medical and public health issues // Transactions of the American clinical and Climatological Association. Nashville, 2005. Vol. 116. P. 127-154.
2. Zavariz C., Glina D.M. Clinico-neuro-psychological evaluation of workers exposed to metallic mercury in the electric lamp industry // Revista de Saude Publica. Sao Paulo, 1992. Vol. 26, No. 5. P. 356-365.
3. Mercury and health. [Electronic resource]. - 2017. - Access mode: https://www.who.int/news-room/fact-sheets/detail/mercury-and-health (date of request 01.06.2021).
4. Hong Y.S., Kim Y.M., Lee K.E. Methylmercury exposure and health effects // Journal of Preventive Medicine and Public Health. Daegu, 2012. Vol. 45. P. 353363.
5. Bagdulina E.N., Tsygankova O.V., Bondareva Z.G., Starichkov A.A., Latyntseva L.D. Diagnostic significance of daily monitoring of arterial pressure in young women (up to 40 years) with arterial hypertension. Moscow, 2015. Vol. 1, No. 1. P. 2009-2014.
6. Hu X.F., Singh K., Chan H.M. Mercury Exposure, Blood Pressure, and Hypertension: A Systematic Review and Dose-response Meta-analysis // Environmental Health Perspectives. Washington, 2018. Vol. 126, No. 7. P. 076002-1076002-15.
7. Houston M.C. Role of Mercury Toxicity in Hypertension, Cardiovascular Disease, and Stroke // The Journal of Clinical Hypertension. Incheon, 2011. Vol. 13, No. 8. P. 621-627.
8. Gallego-Viñas G., Ballester F., Llop S. Chronic mercury exposure and blood pressure in children and adolescents: a systematic review // Environmental Science and Pollution Research. Luxembourg, 2019. Vol. 26, No. 3. P. 2238-2252.
УДК 666.7
Акрамов Мухаммад Бозорович Akramov Muhammad Bozorovich
Заведующей кафедрой "Энергоэффективных и ресурсосберегающих технологии" «МИСиС», к.ф-м.н, доцент. Саидмуродов Мубориз Рахимович Saidmurodov Muboriz Rakhimovich Студент 5 -го курса Душанбинского Филиала федерального государственного автономного образовательного учреждения высшего образования «Национальный
исследовательский технологический университет»«МИСиС» Head of the Department of Energy Efficient and Resource Saving technologies "
"MISiS", Ph.D., associate professor. 5th year student of the Dushanbe Branch of the Federal State Autonomous Educational Institution of Higher Education "National Research Technological University" "MISiS"
КОМПЬЮТЕРНОЕ МОДЕЛИРОВАНИЕ ПРОЦЕССОВ КИСЛОТНОЕ ИЗВЛЕЧЕНИЯ ОКСИДОВ АЛЮМИНИЯ И ЖЕЛЕЗА ИЗ ОГНЕУПОРНЫХ ГЛИН «ЧАШМАСАНГ»
COMPUTER SIMULATION OF ACID EXTRACTION OF ALUMINUM AND IRON OXIDES FROM REFRACTORY CLAYS " CHASHMASANG "
Аннотация: В статье приводится влияние продолжительности процесса разложения огнеупорных глин «Чашмасанг» на составляющих A12O3 и Fe2O3, от концентрации серной кислоты и температуры. Применяя метод компьютерного моделирования, смоделированы процессы разложения. Предложены регрессионные уравнении процессов.
Abstract: The article presents the influence of the duration of the decomposition process of refractory clays "Chashmasang" on the components Al2O3 and Fe2O3, on the concentration of
