CC BY
9
УДК 00- 13058
Tojiddinova M. lecturer
Pharmaceutical Sciences Department at Andijan State Medical Institute
HIGH RISKS OF ANTIBOTIC RESISTANCE AFTER COVID-19 IN
UZBEKISTAN
Abstract: After COVID-19 pandemic, it turned out that antibiotic resistance is getting more and more actual problem in Uzbekistan. Because of overusing antibiotics in pandemic period bacterias are becoming stronger against ordinary antibiotics. The paper was intended to make society tuned in front of status quo in medicine. To stay against bacterial resistance against antibiotics we have to use medications appropriately.
Key words: bacterial infections, post-COVID-19, pandemic, antibiotics, resistance, bacteria, infections.
Introduction
Antibiotic resistance is a growing concern in the medical community, as bacteria continue to evolve and develop resistance to the drugs used to treat them. The emergence of COVID-19 has further exacerbated this issue, as the widespread use of antibiotics to combat secondary bacterial infections in COVID-19 patients has led to an increase in antibiotic resistance. This article will explore the high risks of antibiotic resistance after COVID-19 and the measures that can be taken to mitigate them.
The Risks of Antibiotic Resistance
Antibiotic resistance occurs when bacteria evolve to become resistant to the drugs used to treat them. This can occur through a variety of mechanisms, including mutations in the bacterial genome, horizontal gene transfer, and selective pressure from antibiotic use. The overuse and misuse of antibiotics have been major drivers of antibiotic resistance, as bacteria are exposed to these drugs at sublethal doses, allowing them to develop resistance over time.
The emergence of COVID-19 has further heightened the risks of antibiotic resistance. COVID-19 patients are often prescribed antibiotics to treat secondary bacterial infections that can arise during the course of the disease. This has led to a surge in antibiotic use, which in turn has created a favorable environment for the development and spread of antibiotic-resistant bacteria.
Moreover, COVID-19 has disrupted the supply chains of antibiotics, which has led to shortages of these drugs in many parts of the world. This has forced healthcare providers to use antibiotics more sparingly, which can lead to suboptimal dosing and treatment outcomes. Additionally, the COVID-19 pandemic has created an environment in which infection prevention and control
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measures have been strained, leading to increased transmission of antibiotic-resistant pathogens.
Mitigating the Risks of Antibiotic Resistance
To mitigate the risks of antibiotic resistance after COVID-19, several measures can be taken. First, healthcare providers should ensure that antibiotics are used judiciously and only when necessary. This can be achieved through the implementation of antibiotic stewardship programs, which promote the appropriate use of antibiotics and monitor antibiotic prescribing practices.
Second, infection prevention and control measures should be strengthened to reduce the transmission of antibiotic-resistant pathogens. This can include measures such as hand hygiene, environmental cleaning, and the use of personal protective equipment.
Third, research and development efforts should be accelerated to develop new antibiotics and alternative treatments for bacterial infections. This can be achieved through increased investment in basic and clinical research, as well as incentives for pharmaceutical companies to develop new antibiotics.
Conclusion
Antibiotic resistance is a significant threat to global health, and the emergence of COVID-19 has heightened these risks. The overuse and misuse of antibiotics during the COVID-19 pandemic have created a favorable environment for the development and spread of antibiotic-resistant bacteria. To mitigate these risks, healthcare providers should ensure that antibiotics are used judiciously, infection prevention and control measures should be strengthened, and research and development efforts should be accelerated to develop new antibiotics and alternative treatments for bacterial infections. By taking these measures, we can reduce the risks of antibiotic resistance and ensure that we have effective treatments for bacterial infections in the years to come.
References:
1. ANALYZING COLLECTED DATABASE BY USING GOOGLE FORMS TO DETECT AN INCREASE IN THE NUMBER OF FUNGAL INFECTIONS AMONG CHILDREN POST-COVID-19 PERIOD Pazliddinov A. Shokirov A. b06fdc_6c2e1a6b5c4a407bb3aeb667d156848a.pdf (iupr.ru)
2. Antimicrobial resistance and COVID-19: Intersections and implications Gwenan M Knight https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886324/
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