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Section 3. Medical science
8. Golanov A. V., Ilyalov S. R., Kostyuchenko V. V., Pronin I. N. Radiosurgical treatment of brain metastases.//Proceedings of the IX Russian Cancer Congress on November22-24, 2005, Moscow.
9. Grigoreva V N., Chudakova I. V Quality of life in patients with brain tumors.//Neurological Bulletin. № 2. 2007. - P. 28-32.
10. Grinberg M. S. Neurosurgery. - M: MEDpress-inform, 2010.
11. Danilov V I., Alekseev A. G. Primary tumors of the central nervous system in the Republic of Tatarstan (clinical epidemiology and organization of health care).//Journal Problems of Neurosurgery after N. N. Burdenko. № 3. 2006. - P. 34-38.
12. Zozulya Y. A., Nikiforova A. N, Packo Y. V Epidemiological studies in neuro-oncology: current state in Ukraine and abroad.//Journal Problems of Neurosurgery after N. N. Burdenko. № 3. 1998. - P. 50-54.
13. Karahan V B. Primary and metastatic tumors of the central nervous system.//Problems of clinical medicine. № 1. 2009. -P. 10-21.
14. Kozlov A. V Hereditary diseases in neuro-oncology.//Journal Problems of Neurosurgery after N. N. Burdenko. № 3. 2003. -P. 33-35.
15. Kosmachev M. V., Poshataev K. E., Kapitonenko N. A., Korablev V N. Epidemiology and organization of medical care for patients with brain tumors in large remote regions of the Russian Federation (by the example of Khabarovsk territory).//Far East Medical Journal. № 3. 2009. - P. 35-39.
16. Lavrov A. Y., Modern aspects of pathogenesis, diagnosis and treatment of tumors of the central nervous system.//Journal of Neurology. № 6. 2004. - P. 49-56.
17. Mahnev V V Prognostic factors and improvement of the approach to comprehensive treatment of primary brain tumors based on their clinical and morphological characteristics.//Abstract of dissertation for the degree of Candidate of Medical Sciences. - Ufa, 2012.
18. Moguchaya O. V., Shhedrenok VV., Zahmatov I. G., Ulitin A. Y. Quality issues and evaluation in health care for patients with brain tumors.//Bulletin of Surgery after I. I. Grekov. № 5. 2012. - P. 91-93.
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Tambieva Fatima Ismailovna, Student, Stavropol State Medical University;
Shevchenko Petr Petrovich, PhD, assistant of Neurology department, Stavropol State Medical University, Karpov Sergey Mihaylovic, MD, professor, Stavropol State Medical University E-mail: potoshka282@gmail.com
Features of debut of pediatric multiple sclerosis
Abstract: This article is devoted to study of children’s multiple sclerosis (MS), which is an urgent problem of modern medicine. In recent years MS incidence among children increased significantly all over the world including Russia. A lot of causes of MS remain unexplored but there already have been done a great breakthrough in discovery of pathogenic mechanisms of development of inflammatory and destructive process.
Keywords: multiple sclerosis, children.
Topicality: Until recent time multiple sclerosis was considered to be an adult disease only. But now it is established that in last decades children’s cases ofthe disease are being recorded more often; moreover, in recent years the incidence of MS has increased significantly all over the world and, particularly, in Russia.
Purpose of the article: Analysis of the debut of multiple sclerosis in children.
Results: Due to the fact, that in childhood multiple
sclerosis is usually monosemeiotic, diagnosis is significantly
complicated. After long attack comes long remission, that’s why diagnosis is mostly retrospective, when there is aggravation of multifocal lesions of the nervous system. Among the risk factors of MS in children a special attention is paid to structural changes in the white matter of the brain, that are found in newborns with hypoxic encephalopathy [6]. By the age of six months the amount of healthy children’s antibody titers is almost equal to normal limit of adults, and, at the same time, 12% of 2-3 year children are being identified
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A state of visual analyzer according to the reverse color chees type pattern in case of patients with type 1 diabetes
to have antibody titers to galactocerebroside, and the amount ofwhich 2 times exceeds an adults’ usual amount of titers [7]. It’s already known that the level of antibody production to glutamate receptors is also dependent on the age. In some children those titers remain for a long time. It must be emphasized that increased titers of antybodies to galactocerebro-sides, which are contained in the myelin membranes and cells myelin-producing cells, and to glutamate receptors, which activate neurotransmitter nitrogen oxide production, having a direct toxic effect on oligodendrocytes, create background for the development of demyelinating process in the central nervous system. Debut of MS at the age of 10 years implies
a more favorable course of the disease, whereas the debut at the age of12-14 characterized by severe course with frequent exacerbations [8].
Summary: Thequestion about the prognosis of multiple sclerosis, which debut in childhood remains unsolved. There are a lot of cases of benign and malignant course of MS in children. Taking into consideration the difficulty of clinical diagnosis of MS in childhood, only complex approach using modern methods of examination allows making an early diagnosis and appropriate treatment, provide an important adherence which is essential to prevent progression of disease and deterioration of the patient.
References
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9. Karpov S. M., Pazhigova Z. B., Karpova E. N. Visual evoked potentials in examining the visual analyzer in patients with multiple sclerosis. Neurology, Neurolopsychiatry, Psychosomatics, 2014, number 3, 27-31.
Frantseva Anastasia Petrovna, Karpov Sergey Mihailovich, Khatuaeva Aminat Aubekirovna, Stavropol Medical State University, Assistant of the Neurology Department E-mail: a-frantseva@rambler.ru
A state of visual analyzer according to the reverse color chees type pattern in case of patients with type 1 diabetes
Abstract: The visual analyzer with an evaluation of its functional state at the time of the pulse and the response of the cortical structures presented stimuli. Results of the study revealed that diabetes mellitus in the structures of the visual analyzer significantly (p <0,01) increased in the latent period of the colored stimulus, relative to the control group and the performance of black and white pattern.
Keywords: diabetes, evoked potentials, visual analyzer.
Introduction
Among the pathological conditions of the nervous system, resulting in diseases of the endocrine glands, a special place is occupied by neurological disorders in diabetes mellitus (DM) [1]. This is due not only to the prevalence of these disorders, but their severity, a significant influence on the
prognosis and quality of life. DM is one of the most common diseases in the world. According to experts, by 2025 the total number of people with diabetes will reach 324 million people [3; 7; 11]. Currently, in Russia, about 8 million people suffer from diabetes and the number is constantly growing. [11] Despite the fact that the proportion of type 1 diabetes from
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