CC BY
25
BHopagHKa^w u AHTHOKCHgaHTbi 2018 TOM 5, №3
99
EVALUATION OF THE EFFECT OF OZONE THERAPY ON THE OSSEOINTEGRATION OF DENTAL IMPLANTS Iman Mohamed Sobhy
Alexandria University, Alexandria, Egypt
Pharos University in Alexandria, Alexandria, Egypt
International Scientific Committee of Ozone Therapy (ISCO3)
The success of dental implants has been attributed to osseointegration or direct contact of the implant surface and bone.
The purpose of this study was to evaluate the effect of ozone therapy on the osseointegration of dental implants inserted in experimental animals as well as in patients received implant supported mandibular overdentures.
Eight New Zealand white mature male rabbits were received 16 dental implants inserted in both tibiae, as well as in eight completely edentulous male patients were received mandibular implant overdentures supported by two implants in the canine area. The implants in the right tibiae and in the right canine regions (control group) were inserted by the conventional method. The implants in the left tibiae and left canine regions (test group) were inserted by the conventional method nevertheless; irrigation with ozonized water of 25^g/mL concentration was applied during the osteotomy procedure. Ozone gas of 60 ^g/mL concentration was applied topically in the performed osteotomy sites before the insertion of the implants. After implantation two rabbits were euthanized after two, four, six and eight weeks. The tibiae were dissected from each rabbit and specimens were prepared for histologically and histomorphometric analysis. Clinical and radiographic evaluations were carried out for every patient at the time of loading the prosthesis, then three, six and up to 12 months respectively. Within the limits of this study, the results suggest that the success of osseointegration of the dental implants was achieved in both groups. Moreover, the ozonized group may reveal acceleration of osseointegration, also it may influence bone density in peri-implant interface.
Key words: dental implants, ozone therapy, osseointegration, experiment
