CC BY
359th multidisciplinary international
Conference of Biological Psychiatry
«Stress and Behavior»
Proceedings of the 9th International Multidisciplinary Conference «Stress and behavior» Saint-Petersburg, Russia, 16-19 May 2005 Editor: Allan V. Kalueff, PhD
CONFERENCE ABSTRACTS
4. EXPERIMENTAL MODELS: M.A. DERYAGINA MEMORIAL SYMPOSIUM
ESTIMATION OF OXIDATIVE STRESS RESPONSE OF SEXUALLY MATURE STRESS-RESISTANT PIGS
A.M. Guskov, A.N. Makarenko, S.N. Himicheva, N.N. Sergeeva
Orel State Agrarian University, Orel, Russia Modern technologies of industrial pig-breeding deal with various experimental effects on animal organism. Indispensable condition for the technology of industrial manufacturing of pig-breeding production is high concentration of livestock and heavy use of animals. This results in weakening of general resistance of organism and in production loss (Gorizontov P.D.). The research objective was to study oxidative stress influence on blood values and fat thickness of pigs. The work has been completed on 20 mature male and female pigs weighting from 90 to 100 kg. Control group was kept under the standard zootechnology conditions. Test group was kept at higher density. On Day 1, stress state coincided with the following changes in the blood: the count of segmentonuclear neutrophils authentically increased by 49.7%, the count of stab neutrophils increased almost twice, the count of lymphocytes was greater by 50.9%, while the count of eosinophiles was reduced by 24.5% that evidence the development of initial periods of animals' stress response. We have also noted some increase of whole protein count in blood by 11.7%, and gamma globulins by 19.7%. Fat thickness of the test group decreased by 1.6 mm, clearly indicating intensification of neutral lipid mobilization from depot. Analysis of the obtained result shows that increased density of pigs placement leads to disturbance of animals' functional homeostasis, and results in higher stress responses.
Psychopharmacol. Biol. Narcol. 2005. Vol. 5, N 2. P. 902
Psyhopharmacology & biological narcology
ISSN 1606-8181
