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Section 8. Medical science
Gadzhieva Asiyat, Shevchenko Pet, Vishlova Irina, Stavropol State Medical University, Department of neurology, neurosurgery and medical genetics E-mail: [email protected]
Epidemiology of neurosyphilis
Abstract: The problem of neurosyphilis remains one of the most important in health care. Central nervous system syphilis is often irreversible, involves disability and harm not only to the families of the patients, but also to society as a whole.
Keywords: neurosyphilis, epidemiology, diagnosis.
Neurosyphilis — the defeat of the nervous system in syphilis infection, which can occur at any stage of the infection depends on the causative agent of syphilis hit in the brain tissue. The disease involves complex symptoms of the nervous system that with the growth of the disease vary, forming various manifestations of neurosyphilis. Despite the control measures, the incidence of syphilis remains high [5; 6].
The increase in the incidence of the neurosyphilis according to the long-term supervision lags behind the overall indicators relating to syphilis for 5-10 years. About 15 years ago
O. K. Loseva and colleagues in the journal “Doctor" published an article entitled “Neurosyphilis returns” [4]. Today, we must acknowledge that neurosyphilis “back.”
Currently, the National Assembly has been steadily increasing incidence and prevalence of the disease to various forecasts for 2020 may exceed 25 100 000 population, and the incidence of the manifest of the National Assembly in 2020 may exceed 25 100 000 population.
In neurosyphilis epidemiology in modern conditions may also affect late-seeking patients treated in unlicensed commercial centers, the widespread use of durant penicillin not provide sufficient antibiotic concentration against trepo-nem in the CSF. One reason for the increase in incidence of neurosyphilis may be his untimely and low-quality diagnosis (lack of consultation neurologist, internist, ophthalmologist, otolaryngologist and liquorologic Research), which entails the appointment of inadequate treatment, which naturally leads to an increase in the number of patients with neurological and psychiatric disorders [1; 2; 3].
The purpose of the study
To study the epidemiology of neurosyphilis in the Stavropol region.
Materials and methods
The incidence of neurosyphilis was analyzed on the basis of the archives of the library and the hospital data the Internet data.
Results and discussion
There have been studies of cognitive impairment in patients with an established diagnosis — neurosyphilis (neuropsychological testing). The data revealed the most significant cognitive changes in this group of patients, which may be due to more pronounced specific degenerative process in the brain tissues.
Considering that at the present stage for the National Assembly is erased, asymptomatic nature of the use of neuropsychological testing in conjunction with neurophysiological research methods may be a more objective way to detect cognitive impairment than an attempt at the clinical stage, focus on the characteristic symptoms of the late manifestations neyrosifilitic encephalopathy where the clinical picture can simulate any neuropsychiatric symptoms, which often leads to misdiagnosis and incorrect treatment. All this will help at an earlier date to diagnose neurosyphilis and will reduce the number of patients.
Conclusion
In recent years, the number of patients with neurosyphilis increased significantly. Often this is due to his untimely diagnosing. In order to prevent the development of neurosyphilis is necessary to monitor the state of the nervous system in patients with latent forms of syphilis during the period of clinical and serological monitoring.
For early diagnosis of neurosyphilis is necessary to introduce in hospitals carrying out neurophysiological and sonographic studies.
References:
1. Васильева О. А., Карпов С. М., Казиев А. Х. Когнитивные нарушения при позднем нейросифилисе.//Неврологиче-ский вестник. - 2012. - Т. XLIV, вып. 1 - С. 10-13.
2. Васильева О. А., Кубрин Е. А., Карпов С. М., Шевченко П. П. Поздний нейросифилис как фактор когнитивных нарушений.// Фундаментальные исследования. - 2012. - № 4-2. - С. 256-259.
3. Казиев А., Карпов С. М., Кубрин Е. М. Показатели когнитивных функций мозга при нейросифилисе.//Практическая неврология и нейрореабилитация. - 2010. - № 2. - С. 43.
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Physical activity and bone mass density in p-thalasemia subjects (A Review)
4. Лосева О. К. Современный нейросифилис: клиника, диагностика, лечение./О. К. Лосева, Э. Ш. Тактамышева//РМЖ. -1998. - Т. 6. - № 15. - С. 21-23.
5. Попов А. К., Одинак О. М. Нейросифилис.//Дифференциальная диагностика нервных болезней/Под ред. Г. А. Акимова и М. М. Одинака. - СПб, 2000. - С. 349-354.
6. Яковлев Н. А. Нейросифилис (клиника, диагностика и лечение): уч.пос./под ред. В. В. Дубенского. - Тверь, 2004. - 175 с.
MSc. Genti Pano, PhD Student at Sport Sciences Research Institute, Department of Physical Activity Health and Recreation Research,
Sports University of Tirana, Albania E-mail: [email protected] Qna Robert,
Prof. Assoc. Dr., Deparment of Sport Medicine, Faculty of Movement Sciences, Sports University of Tirana, Albania
Physical activity and bone mass density in p-thalasemia subjects (A Review)
Abstract: Beta thalassemia is a blood disorder that reduces the production of hemoglobin. Patients with thalassemia show a variety of bone disorders that include bone deformities, osteopenia and osteoporosis, growth failure, and spinal deformities Karimi [6].
Main objective of this paper was to review the recent literature regarding physical activity influence on bone mass density in ^-thalassemic subjects.
The search was made mainly focusing in PubMed, ResearchGate, Hinari, for studies focusing on PA intervention in в-thalassemia subjects. Only 6 papers fulfilled the inclusion criterias.
There is a lack of studies focusing in PA influence on bone mass density in these patients category. Further research is needed to identify risk factors, means of prevention and also to establish specific PA engagment guidelines and recomandations for this social category.
Keywords: Thalassemia, Bone mass density, Physical Activity.
Haemoglobin Disorders
Beta thalassemia is a blood disorder that reduces the production of hemoglobin. Patients with thalassemia show a variety of bone disorders that include bone deformities, osteopenia and osteoporosis, growth failure, and spinal deformities [6]. Beta (в-) thalassemia syndromes of which в-thalassemia major, also known as Mediterranean anemia or Cooley’s Anemia, is the clinically most severe one.
The major beta (в-) thalassaemia syndromes are:
• в- thalassemia;
• в-thalassemia intermedia;
• ^E^-thalassemia;
• Other rare thalassemia’s.
Approximately 7 % of the global population is a carrier for Hemoglobin disorders. A carrier of a pathological Hb gene encounters no health problems. Between
300.000- 500,000 children are born annually with a severe hemoglobin disorder. About 80 % of affected children are born in middle and low income countries. About 70 % are born with sickle cell and the rest with thalassemia disorders. 50-80 % of children with sickle cell anemia and
50.000- 100,000 children with в-thalassemia major die
each year in low and middle income countries World Bank 2006 [9], (report of a joint WHO-March of Dimes meeting 2006). Patients with в-thalassemia major, the most severe form of thalassemia, cannot make adult hemoglobin, and as a consequence cannot produce normal red blood cells. In these individuals, each red blood cell contains much less hemoglobin, and there are far fewer red cells than the normal range. This causes anemia, which is severe in these patients. A child with в-thalassemia major does not, however, develop severe anemia until 3 months to one year of age. If left untreated, affected children have a very poor quality of life and most will die at a very young age. The basic components of management in these patients are blood transfusion and iron chelation.
Objectives
Main objective of this paper was to review the recent literature regarding physical activity influence on bone mass density in thalassemic subjects (ft-thalassemic specifically).
Methods
The search was made mainly focusing in: PubMed, ResearchGate, Hinari, for studies focusing on PA intervention in в-thalassemia subjects.
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