ENHANCED ANTIBACTERIAL ACTION OF SILVER NANOPARTICLES LOADED ON REDUCED GRAPHENE OXIDE SHEETS UNDER BLUE-LIGHT IRRADIATION Текст научной статьи по специальности «Биологические науки»

ENHANCED ANTIBACTERIAL ACTION OF SILVER NANOPARTICLES LOADED ON REDUCED GRAPHENE OXIDE SHEETS UNDER BLUE-LIGHT IRRADIATION

ANDERSON R. L. CAIRES*

Optics and Photonics Group, Institute of Physics, Federal University of Mato Grosso do Sul, Campo Grande, Mato

Grosso do Sul, 79070-900, Brazil. anderson.caires@ufms.br

ABSTRACT

The main motivation is to show that an efficient process of bacterial inactivation can be achieved by using silver nanoparticles (AgNPs) anchored on graphene oxide (GO) sheets under blue light illumination. It will be presented general motivations on: multi-drug microorganisms; antimicrobial photodynamic therapy (aPDT); nanoparticles in aPDT; photodynamic action of AgNPs; and enhanced photodynamic effect of AgNPs loaded on graphene oxide (GO). Finally, it will be shown a recent published study, which demonstrates that an enhanced antibacterial action of AgNPs-GO, against Staphylococcus aureus, under blue-light illumination can be achieved because of three different bacterial killing processes: (i) chemical effect promoted by Ag+ ion release from AgNPs; (ii) photodynamic activity induced by AgNPs-GO, enhancing the bacterial photoinactivation due to the excited-Plasmons of the AgNPs when anchored on r-GO; and (iii) photodynamic effect promoted by bacterial endogenous photosensitizers under blue-light irradiation.

Keywords: Antimicrobial photodynamic therapy; Silver nanoparticle; Graphene oxide; Blue light; Staphylococcus aureus.