DISTRIBUTION VARIANTS OF SOMATOTYPE IN HEALTHY AND PATIENTS WITH ACNE BOYS AND GIRLS FROM PODILSKY REGION OF UKRAINE

Set peculiarities of distribution variants somatotype in healthy and patients with acne boys and girls from Podilsky region of Ukraine. In patients with acne compared with healthy young boys found significantly higher percentage of people mesomorphic and meso-endomorphic somatotype and a smaller percentage of people ecto-mesomorphic somatotype. In patients with acne girls compared with healthy girls found significantly higher percentage of people mesomorphic and a smaller percentage of people endomorphic somatotype. The rest of the percentages by somatotype (ectomorphic and medium intermediate in both sexes, and ecto-mesomorphic and meso-endomorphic in girls) between patients and normal subjects were not significantly differ. As in boys and in girls were not found significant differences or trends in the distribution variants somatotype between groups of patients with acne of various degrees of severity. Material and methods. Done clinical laboratory and anthropological examination of 84 patients with acne boys (mild severity - 42, moderate – 31, severe severity - 11) and 116 patients girls (mild severity - 72, moderate - 39, severe severity - 5) residents Podilsky region of Ukraine. The results are compared with data of anthropo-somatotypological survey of 150 healthy boys and 160 girls of similar age and region of residence from the data bank of scientific and research center Vinnitsa National Medical University named after M.I. Pirogov. Used the following methods: general clinical - to verify the diagnosis and severity of acne [16]; anthropometry by the method of V.V. Bunak in modification of P.P. Shaparenko [19]; somatotype determination by the method of J. Carter and B. Heath [2]; statistical analysis of the results carried out in the license statistical package ―STATISTICA 6.0‖. Results and its discussion. As a result of the research distribution of somatotypes in healthy and patients with acne boys and girls established: - greater (p <0.05) the percentage of boys mesomorphic somatotype among patients with mild acne severity (64.3%) than among healthy young men (46.7%) and greater (p <0,05-0,01) percentage of girls similar somatotype among patients with acne in general (39.7%) and among patients with acne of moderate severity (43.6%) than among healthy women (24.4%); - greater (p <0.05) percentage of healthy girls endomorphic somatotype (4.4%) compared with patients with acne girls in general (0%); - greater (p <0,01-0,001) percentage of healthy young men ecto-mesomorphic somatotype (22.0%) than in patients with acne youths in general (4.8%) than in boys and patients with mild acne severity (2,4%); - smaller percentage (p <0,05-0,01) In the article the cephalometric parameters which are used in the analysis of Charles H. Tweed International Foundation and their importance for young people Podilskiy region of Ukraine with orthognathic bite, assessment of sexual differences of these parameters and the comparison of obtained results with normative data which are used by Charles H. Tweed International Foundation and normative data of H. Stockfisch for the European population. Established gender and ethnic differences point to the need to create a normative base of cephalometric indicators used in the analysis of Charles H. Tweed International Foundation for the population of Ukraine.

Acne -a disease which in one form or another during the life suffer up to 95% of the population of civilized countries [5,8]. In recent years, acne is no longer a just teenage disease and often occurs in adolescence and adulthood. It is known that post inflammatory skin changes disturb most patients not less than the actual manifestations of acne, it adjusted difficult and often remain forever, which also reduces the quality of life of patients [8,20]. Dermatology is an urgent need before nosology problem of diagnosis and prevention of the formation of pronounced skin blemishes that will significantly reduce the psychosocial consequences of the disease, improve quality of life and reduce overall costs for the treatment of acne and correcting its effects [17].
The basis of all state norms and pathology is interaction peculiarities of organism of genetic and environmental factors. In fact, the genetic component gives an explanation of individual differences in susceptibility to a particular disease and causes a different degree of its manifestation and susceptibility to various means of therapy [11]. Multifactor pathology to which the acne include is characterized by polygenic predisposition, which is implemented through specific inherent features of genotypic constitution norm of reaction [14]. Of course, problems in the study of predisposition to acne one of the promising is constitutional approach, which involves the study of private subsystems of general constitution of man and can detect internal communications between private constitutions and structuralfunctional state of organism [13], including acne. The most complete picture of the overall human constitution gives somatotype (private bodily constitution). It is important to emphasize that a predisposition to acne and features of the constitution is largely caused by genetic factors [1], thus suggesting the relationship of physical types with a predisposition to this dermatosis [9]. In addition, the constitutional approach could promote primary prevention among persons who due to the peculiarities to their constitutions tend to the appearance of acne [17].
The purpose of research -identify the characteristics of distribution variants somatotype in healthy and patients with acne boys and girls Podilsky region Ukraine.
Material and methods. Done clinical laboratory and anthropological examination of 84 patients with acne boys (mild severity -42, moderate -31, severe severity -11) and 116 patients girls (mild severity -72, moderate -39, severe severity -5) residents Podilsky region of Ukraine. The results are compared with data of anthropo-somatotypological survey of 150 healthy boys and 160 girls of similar age and region of residence from the data bank of scientific and research center Vinnitsa National Medical University named after M.I. Pirogov. Used the following methods: general clinical -to verify the diagnosis and severity of acne [16]; anthropometry by the method of V.V. Bunak in modification of P.P. Shaparenko [19]; somatotype determination by the method of J. Carter and B. Heath [2]; statistical analysis of the results carried out in the license statistical package -STATISTICA 6.0‖.
Among the variety factors of acne one of the priorities is to study constitutional features of a person, which, along with the same unmodified risk factors as age, gender, ethnicity, important to consider when assessing the cumulative risk of dermatosis [4,14]. It has been proved that people who belong to certain physical types is susceptibility to various diseases, and one and the same diseases in different constitutions of subjects have different course [11]. It is natural to assume that course of acne will depend on the characteristics of constitution. So in researches Koshel M.V. [15] found that the severity of acne has pronounced inverse correlation with fat component of body weight and thickness of skin and fat folds. However, in our studies, between severity of acne and somatotype author, like other scientists [10,12,13] found no difference that explains heterogeneity of pathological process and needs to explore other parts of pathogenesis that affect the nature of the dermatosis.
In several studies has been shown relationship between hyperproduction of active androgens in the skin and acne. The high levels of testosterone and low estrogen levels was associated by authors with increased activity of the sebaceous glands and therefore with acne, dermatitis, accompanied by hyper seborrhea [3,7,18]. However, phenotype mesomorphic somatotype corresponds with prevalence of androgen and endomorphic -phenotype with a predominance of estrogen [3,4]. That is why, compared with representatives of mesomorph somatotype in endomorph developed of acne is less common. According to the survey results Hendohina Ya.O. [10] in boys of breast somatotypes acne diagnosed less common compared with boys of muscle, belly and uncertain Somatotypes. When analyzing the components of somatotype Chebotarev V.V. et al. [6] found that among patients with acne in 52% of cases observed prevalence of mesomorphic somatotype component, in 21.3% of cases -endomorpic somatotype component, and in 20.0% of cases -ectomorphic component of somatotype. The present study in relation to the given literature data allows to summarize and supplement existing information that investigated mesomorphic somatotype include the risk for the possibility of occurrence of acne.