CC BY
27PH-I-8
Direct laser writing technique for creating non-enzymatic sensors
V. Andrianov1, E. Khairullina1, A. Smikhovskaia1, V. Mironov1, M. Panov1, M. Mizoshiri2, I. Tumkin1
1Saint Petersburg State University, Institute of Chemistry, Saint Petersburg, Russian Federation 2Nagaoka University of Technology, Dept. of Mechanical Engineering, Nagaoka, Japan
The development of the modern methods for fabrication of new nano- and microcomposite materials is quite important for medicine, science, and industry [1]. In recent years, more and more interest has been paid to the development and production of next-generation sensors, in which electron transfer does not occur through a mediator, but directly to the electrochemically active centers of the surface layer of a sensor material. This allows to significantly increase the analytical signal as well as improve sensitivity and selectivity.
In this work, the metallic and bimetallic electrodes will be fabricated using two methods: Laser-induced Chemical Liquid-phase Deposition of metals from solution (LCLD) [3] and reactive Selective Laser Sintering (SLS) [4]. Both approaches are related to Direct Laser Writing (DLW) techniques, the common feature of which is the localized interaction of laser radiation with the precursor leading to the initiation of a given chemical reaction and subsequent deposition of the required material on the surface of a substrate.
We used ceramic as well as polymeric (flexible) substrates, which are promising for creating flexible devices. The electrochemical measurements showed that metallic and bimetallic microelectrode created by Direct Laser Writing (DLW) techniques significant improvement of the sensor characteristics as compared to that of pure copper and many other analogs. Microelectrodes were used as working electrodes for electrochemical detection of such bioanalysts as glucose, hydrogen peroxide and amino acids.
I.I.T. thanks the Fellowship of President of Russia MK-6153.2018.3. The authors also express their gratitude to the SPbSU Nanotechnology Interdisciplinary Centre, Centre for Optical and Laser Materials Research, Centre for X-ray Diffraction Studies and Chemistry Educational Centre.
References
[1] B.D. Ratner, A.S. Hoffman, F.J. Schoen, J.E. Lemons, Biomaterials Science: An Introduction to Materials in Medicine, third edition, Academic Press, 2012.
[2] W. Liu, H. Zhang, B. Yang, Z. Li, L. Lei, X. Zhang, A non-enzymatic hydrogen peroxide sensor based on vertical NiO nanosheets supported on the graphite sheet, J. Electroanal. Chem. 749 (2015) 62-67.
[3] A.V. Smikhovskaia, M.S. Panov, I.I. Tumkin, E.M. Khairullina, S.S. Ermakov, I.A. Balova, M.N. Ryazantsev, V.A. Kochemirovsky, The in situ laser-induced codeposition of copper and different metals for fabrication of microcomposite sensor-active materials, Anal. Chim. Acta 1044 (2018) 138— 146.
[4] S. Arakane, M. Mizoshiri, J. Sakurai, S. Hata, Direct writing of three-dimensional Cu-based thermal flow sensors using femtosecond laser-induced reduction of CuO nanoparticles, J. Micromech. Microeng. 27 (2017) 055013.
