CC BY
13B-PS-1
Determination of stress-related characteristics of blood vessel walls using endoscopic optical coherence elastography
A. Potlov1, S. Frolov1, T. Frolova1, S. Proskurin1
1Tambov State Technical University, Biomedical Engineering, Tambov, Russian Federation
An original approach to assess the stress-related properties of large blood vessel walls is described. Structural images of the investigated part of the blood vessel wall are sequentially obtained using endoscopic optical coherence tomography (EOCT) before the deforming impact and during the process of the deforming impact. Pulse wave is used as the deforming force. The surface area of the deforming force is considered to be equal to the scanning area of an EOCT system. Structural images specific test points are determined corresponding to the moments of systole and diastole. The above points are grouped in pairs. For each pair the vector value of the relative displacement is calculated. Then, the displacement values are independently resolved into components. The longitudinal displacements for each pair of the test points are considered to be equal to the projections of the vectors on the Y-axis. Sizes of the deformable region are calculated by combining the longitudinal displacements for all pairs of the test pixels. The transverse displacements and transverse dimensions for the X-axis are to be found the same way. Further, the values of Young's modulus and Poisson's ratio are calculated using the classical formulas.
The presented approach can be used in analyzing atherosclerotic plaque in vivo, determining the likelihood of correct deployment of the flow-diverter, assessing the accuracy of the flow-diverter deployment post factum, predicting the duration of the positive effect of stenting of the cerebral artery with aneurysm post factum and the feasibility of further surgical procedures. This work was supported by the Russian Science Foundation (RSF project 16-15-10327).
