CC BY
42
BecmHUK Kß^HJy №4-2018
UDC 617-089 615.468.6
D.A. Abildayev, Zh.A. Semzhanova, L.Sh. Abdullayeva, A.Y. Aitberdiyeva
Asfendiyarov Kazakh National medical university, Course of Clinical Anatomy and Operative Surgery
COMPARATIVE CHARACTERISTICS OF MODERN SUTURE MATERIAL
(REVIEW)
Authors performed an updated and thorough review of the literature regarding modern suture materialA comprehensive literature review was conducted through the search in the databases Pubmed, Google Scholar, Cochrane Library, using the keywords suture, suture techniques, suture material.Were described data on the qualities ofthe ideal suture, general classification, comparative characteristics of different types of suture materials.lt was possible to synthesize the current knowledge about present suture material and present their peculiarities according to examined laboratory findings. Keywords: suture, suture material, regeneration
Introduction.
Each surgical operation requires the application of adequate suture material, taking into account the general condition and age of the patient, the presence of infection and inflammatory process, a high risk of thrombosis and etc. Thus, one of the problems, defining the further progress of modern medicine is the creation of suture materials, most rational in this or that surgical situation. For the first time, the suture thread was used for closing wounds 3.500 years before Christ in Egypt. [1] In the past centuries, there have been many stitching matters, for instance, animal tendons, horsehair, leather strips, clod fibres, and human hair. [2] In 1806, Philip SyngPhysick developed a firm absorbable suture made from buckskin, [2] basically developing the current suture technique. Still, nowadays, there is a search for an ideal suture material.
Ideal suture material should:
1. Have stable handling properties; 2. Not provoke tissue response; 3. Enable solid knots; 4. Have satisfying tensile force; 5. Not perforate into tissue; 6. Be sterile; 7. Be nonelectrolytic; 8. Be non-allergenic; 9. Cheap. [3] Materials and methods.
A comprehensive literature review was conducted through the search in the databases Pubmed, Google Scholar, Cochrane Library, using the keywords suture, suture techniques, suture material. Totally were found 1132 articles (60 from PubMed, 574 from Google Scholar, 498 from Cochrane Library). From them we have chosen 29 articles, which were relevant for our theme. Discussion and Results.
A comprehensive assortment of stitching materials is available to surgeons today. Suture materials can be broadly categorised on natural and synthetic. [4]
Table 1 [5] - Classification of suture material
Suturematerials
Absorbable Non-absorbable
Natural Synthetic Natural Synthetic
Catgut-plain or Polyglactin (vicryl), Silk, Polyamide (nylon),
chromic polyglycolic acid linen polyester (dacron),
(dexon) polypropylene (prolene)
Besides, they can be monofilament or multifilament (braided), dyed or undyed, coated or uncoated. Various parameters, including suture strength, flexibility, capillarity and thread memory represent a physical characteristic of sutures. [6] Advantages of braided sutures include ease of administration, weak memory and increased knot security. However, bacteria can invade the spaces between fibres, potentially leading to suture infection, granulomas and sinuses. [7] By contrast, a monofilament suture is a single material. These seams have limited tendency of infection, ease of
the passage within tissue and simple removal. Their disadvantages are considerable preservation of package shape, difficult applying, knot insecurity, and perforating the tissue. [8] Generally, braided sutures potentiate more contaminations as opposed to non-braided sutures. When sealing wounds by a braided Vicryl™ suture there is a 100% rate of infection. By contrast, injuries connected by non-braided sutures exhibited a significantly diminished rate of wound infection. [9]
Many surgeons prefer non-absorbable monofilament sutures, while others tend to choose
Vestnik KaxNMU №4-2018
absorbable ones more. [10] The main limitation of non-absorbable sutures is the necessity for their removal within 5 and 10 days next to installation. This requires an extra doctor visit, what is not so beneficial for many patients. As LaBagnara has mentioned in his review of absorbable suture materials, used in head and neck surgery, absorbable sutures are simple to manipulate, have low reactivity and good tensile strength, and cost less than non-absorbable sutures. [11] Luck et al., came with no clinically notable variations in cosmetic appearance between absorbable and non-absorbable sutures after 3 months. [12] Likewise, Karounis et al. did not discover any difference in cosmetic scores between plain catgut versus nylon sutures in paediatric lacerations after 4-5 months.
[13] When compared to absorbable sutures, monofilament nylon ones lessen the risk of hypertrophic scarring mainly in sternotomy scars.
[14]
Vicryl is a type of synthetic absorbable suture and formed of a polymer of glycolide and lactide coated with a mixture of glycolide, lactide and calcium stearate. [15] There is a new formulation of Vicryl called VicrylRapide, which consists of smaller molecules of the same components as Vicryl. [16] VicrylRapide is produced by gamma irradiation of polyglactin 910, which absorbs quickly than Vicryl. [16] Its tensile strength is reduced by 50% after 5 days, in comparison to Vicryl; furthermore, there is no traction left after 14 days. [16] VicrylRapide is fully absorbed after 42 days, whereas Vicryl takes around 56-70 days. Thus, irradiated polyglactin 910 is proper for the closure of scars where fast suture absorption is required, especially for bruises in the scalp, scrotum, and perineum and is an ideal material for mucocutaneous anastomosis at stoma surgery. Loss of suture strength is so accelerated that suture removal is unnecessary, eliminating the necessity for further medical or paramedical care.[17]
The features of irradiated polyglactin 910 do it ideal for full-thickness skin grafts. Linberg observed a similar efficiency of Vicryl and nylon stitches in inhibiting scar dehiscence in an in vivo rat model of oculoplastic surgery. [18]
Polydioxanone (PDS) is a monofilament absorbable thread produced from the polymerization of paradioxanone. The study performed by anastomosis and micro anastomosis with polidioxanone had shown that this type of material has provoked little inflammatory reaction when compared with other materials of suture [19, 20]. Additionaly, nowadays polydioxanone becomes very popular in Facial Rejuvenation procedure. Samira Yaraket. al. in their study reported a series of cases using polydioxanone absorbable monofilament synthetic threads called Mint Lift™. According to results, Mint Lift™ is an alternative for reconstruction and facial rejuvenation in patients
with mild to moderate skin flaccidity, admitted to be minimally invasive and can be performed in a shorter time and under local anaesthesia. It has a definite recommendation in patients who do not want to undergo the routine surgical procedure, do not have free time for recovery, or that do have a contraindication to procedure due to anaesthetic sedation. The procedure has proven to be safe, and a significant improvement was visible in the postoperative period. [21]
Poliglecaprone (Monocril) is an absorbable, monofilament, a copolymer of epsilon-caprolactone and glycoside. Laboratory findings have shown good ease of handling, minimal resistance during crossing in the tissues and tension resistance. The time of total absorption between 90 and 120 days after installation into the tissues, with minimal tissue reaction [22]. Moreover, according to LaBagnara study, where he applied Monocryl in 80 cases, suggest that it has multiple superior characteristics including the comfort of handling, mild tissue reactions, higher tensile strength, and lower cost. [11]
Poliglecaprone-25 (Monocril) and polyglactin-910 (Vicryl Rapid) are two of the most commonly applied absorbable stitches in cutaneous surgery. The study, closure of the deep part of Mohs defects, performed by Thomas Regan and Naomi Lawrence had shown that Poliglecaprone-25 resulted in significantly less projected sutures than did polyglactin-910, although both presented in the same degree of lumpiness and similar-appearing scars at 1 week and 3 months. [23] Cotton, linen and silk aremultifilamentary non-absorbable sutures of natural fibers. They have high resistance, are comfortable to manage and provide a secure mechanical connection. Their benefit is the low cost, reason by which still today are widely used in many hospitals. Nevertheless, they induce the infection more than monofilamentares wires nonabsorbable sutures. Thus, these materials should be avoided in wound suture that show bacterial contamination. Silk, in particular, exerts a significant inhibitory effect on the functions of macrophages, harming mostly the adhesion of these cells [24].
Polytetrafluoroethylene (PTFE) is a non-absorbable monofilament wire, examined with good results in plastic surgery. According to a comparative study with 10 other sutures, it was established that the PTFE induces lesser tissue reaction, making it admitted the material of choice for facial plastic surgery, where the functional and aesthetic results are crucial. [25]
One of the modern world trends in surgery is the use of synthetic non-absorbable sutures for the application of surface removable seams. Within the framework of this direction, new kinds of materials with improved characteristics are developed and introduced into surgical practice [26].
BecrnuuK Ka^HMy №4-2018
A decade ago, V.E. Günther et al. Discussed the possibility of using a thread based on titanium nickelide as a suture [27, 28].
Today this suture material has already been introduced into medical practice. Titanium nickelide provides implants with a new set of properties: shape memory with temperature change, superelasticity at body temperature, corrosion resistance under conditions of prolonged alternating deformation. D.N. Kornilov et al. in the experiment, studied the features of scar formation and its quality when using suture material based on titanium nickelide. As a result, it has been established that a titanium nickelide-based filament
induces the development of a fibrous clutch in the shortest possible time [29].
The literature contains only fragmentary data on the interaction of suture materials based on titanium nickelide with biological tissue. This is not enough for the wide use of new medical products, it is necessary to continue research. Conclusion.
In conclusion, the existing knowledge of sutures and their characteristics contribute to the surgeons decide the proper surgical material for the use, leading to best postoperative results, bypassing rejections, infections and other difficulties inherent to the operative procedure, promoting a quick recovery of the patient.
REFERENCES
1 Snyder C.C. On the history of the suture // PlastReconstr Surg. - 1976. - №58(4). - P. 401-406.
2 Luck RP, Flood R, Eyal D, Saludades J, Hayes C, Gaughan J. Cosmetic outcomes of absorbable versus nonabsorbable sutures in pediatric facial lacerations / / PediatrEmerg Care. - 2008. - №24. - C. 137-142.
3 Filho IA, Neto IA, Wanderley Costa Dantas MH, Sampaio TBM, Rego ACM Surgical Sutures: The Necessary Update of Current Knowledge / / GastroenterolPancreatol Liver Disorder. - 2018. - №6(1). - C. 1-5.
4 Mackenzie D. The history of sutures // Med Hist . - 1973. - №17. - C. 158- 168.
5 Kudur MH, Pai SB, Sripathi H, Prabhu S. Sutures and suturing techniques in skin closure / / Indian J DermatolVenereolLeprol . - 2009. - №75. - C. 425-434.
6 Swanson NA, Tromovitch TA. Suture materials 1980: Properties, uses, and abuses // Int J Dermatol . - 1982. -№21. - C. 373-378.
7 Parell GJ, Becker GD. Comparison of absorbable with nonabsorbable sutures in closure of facial skin wounds. // Arch Facial PlastSurg.. - 2003. - №5. - C. 488-490.
8 Pineros-Fernandez A, Salopek LS, Rodeheaver PF, Drake DB, Edlich RF, Rodeheaver GT. A revolutionary advance in skin closure compared to current methods / / J Long Term Eff Med Implants. - 2006. - №16. -P.19-27.
9 Pineros-Fernandez A, Salopek LS, Rodeheaver PF, Drake DB, Edlich RF, Rodeheaver GT. A revolutionary advance in skin closure compared to current methods / / J Long Term Eff Med Implants. - 2006. - №16. -P.19-27.
10 Parell GJ, Becker GD. Comparison of absorbable with nonabsorbable sutures in closure of facial skin wounds // Arch Facial Plast Surg. -2003. - №5. - P. 488-490.
11 LaBagnara J., Jr A review of absorbable suture materials in head and neck surgery and introduction of monocryl: A new absorbable suture // Ear Nose Throat J. - 1995. - №74. - P. 409-415.
12 Luck RP, Flood R, Eyal D, Saludades J, Hayes C, Gaughan J. Cosmetic outcomes of absorbable versus nonabsorbable sutures in pediatric facial lacerations / / PediatrEmerg Care. - 2008. - №24. - P. 137-142.
13 Karounis H, Gouin S, Eisman H Chalut D, Pelletier H, Williams B. A randomized controlled trial comparing long-term cosmetic outcomes of traumatic pediatric lacerations repaired with absorbable plain gut versus nonabsorbable nylon sutures // AcadEmerg Med. - 2004. - №11. - P. 730-735.
14 Durkaya S, Kaptanoglu M, Nadir A, Yilmaz S, Cinar Z, Dogan K. Do absorbable sutures exacerbate presternal scarring? // Tex Heart Inst J. - 2005. - №32. - P. 544-548.
15 Ratner D, Nelson BR, Johnson TM. Basic suture materials and suturing techniques / / Semin Dermatol. - 1994. - №13. - P. 20-26.
16 Talbot AW, Meadows AE, Tyers AG, Shah-Desai S. Use of 7/0 Vicryl (coated polyglactin 910) and 7/0 Vicryl-rapide (irradiated polyglactin 910) in skin closure in ophthalmic plastic surgery / / Orbit. - 2002. - №21. -P.1-8.
17 Tandon SC, Kelly J, Turtle M, Irwin ST. Irradiated polyglactin 910: A new synthetic absorbable suture // J R CollSurgEdinb. - 1995. - №40. - P. 185-187.
18 Linberg JV, Mangano LM, Odom JV. Comparison of nonabsorbable and absorbable sutures for use in oculoplastic surgery / / Ophthal Plast Reconstr Surg. - 1991. - №7. - P. 1-7.
19 Quesada D, Diago V, Redondo L, Rodriguez-Toves L, Vaquero C. Histologic effects of different suture materials in microsurgical anastomosis of the rat uterine horn / / J Reprod Med. - 1995. - №40(8). - P. 579- 584.
Vestnik KazNMU №4-2018
20 Pihlajamäki HK, Salminen ST, Tynninen O, Böstman OM, Laitinen O. Tissue restoration after implantation of polyglycolide, polydioxanone, polylevolactide, and metallic pins in cortical bone: an experimental study in rabbits // Calcif Tissue Int. - 2010. - №87(1). - P. 90-98.
21 Yarak S, de Carvalho JAR (2017) Facial Rejuvenation with Absorbable and Barbed Thread Lift: Case Series with Mint Lift™ // J ClinExpDermatol Res. - 2017. - №8. - P. 415-421.
22 Bezvada RS, Jomilkowski DD, Lee LY, Agarwal V, Persivale J, Trenka- Benthin S, et al. Monocryl suture, a new ultra- pliable absorbable monofilament suture / / Biomaterials. - 1995. - №16(15). - P. 1141-1148.
23 Lawrence N.Comparison of poliglecaprone-25 and polyglactin-910 in cutaneous surgery / / Dermatol Surg. -2013. - №39(9). - P. 1340-1344.
24 Uff CR, Scott AD, Pockley AG, Phillips RK. Influence of soluble suture factors on in vitro macrophage function // Biomaterials. - 1995. - №16(5). - P. 355-360.
25 Setzen G, Willams EF. Tissue response to suture materials implanted subcutaneously in a rabbit model / / PlastReconstr Surg. -1997. - №100(7). - P. 1788-1795.
26 Tretyak SI, Markevich EV, Buravsky AV. Surgical sutural material / / Guidelines [Khirurgicheskiy shovnyy material. Metodiches kiere komendatsii]. - Minsk: 2008. - 54 p.
27 Gyunter WE, Khodorenko VN, Chekalkin TL, Olesova VN, Dambaev GT, Sysolyatin PG, Fomichev NG. Medical materials with shape memory / / Meditsinskiematerialy i implantaty s pamyat'yuformy. - Tomsk: 2012. - 534 p.
28 Gyunter VE, Khodorenko VN, YasenchukYuF, Chekalkin TL, Ovcharenko VV, Klopotov AA, Dambaev GT, Sysolyatin PG, Fomichev NG, Olesova VN, Mirgazizov MZ, Proskurin AV, Ziganshin RV, Polenichkin VK, Matyunin AN, FatyushinMYu, Molchanov NA, Monogenov AN. Titanium nickelide / / Medical material of new generation [Nikelidtitana.Meditsinskiy material novogopokoleniya]. - Tomsk: 2006. - 296 p.
29 Kornilov DN, Popov IV, RayevskayaLYu, Goldberg OA, Lepekhova SA. Results of application of a super- elastic implant from titanium nickelide in experimental injury of a sinew, morphological justification // Sibirskiy meditsinskiy zhurnal. - Irkutsk: 2006. - №3. - P. 21-25.
Д.А. Абильдаев, Ж.А. Семжанова, Л.Ш. Абдуллаева, А.Е. Айтбердиева
С.Ж. Асфендияров атындагы К,азац Улттыц медицина университету Клиникалыц Анатомия жэне ОперативтжХирургия курсы
КАЗ1РП ЗАМАН МАТЕРИАЛДАРЫНЫН, САЛЫСТЫРМАЛЫ СИПАТТАМАЛАРЫ
(ЭДЕБИ ШОЛУ)
ty^h: 9p6ip хирургиялык операция толыкканды материалды емделушшщ жалпы жагдайы жэне жасына байланысты колдануга, инфекциялар мен кабыну процесстершщ жоктыгын, жогаргы тромбоз к;атерi жэне тагы баска аурулардыц болмайтындыгын талап етедь Осыган орай, ец басты мэселе, заманауи медицинаныц алга басуын аныктайтын, барлык салада колданылатын жаца т^у материалдарын ойлап табу. Бул ма;алада авторлар к^рп заман ттс материалдарыныц эдеби салыстырмалы нускасын жасады, Pubmed, Google Scholar, Cochrane Library секiлдi онлайн ютапханаларын колдана отырып. Тужырымдамада авторлар карастырган тiгiс материалдардыц eзiндiк к;асиеттерi мен жетiспеушiлiктерi бар, жэне эрбiр материалга тужырым , хирургтардыц операция тYрiмен кандай тiнге eзiндiк материал колдануын шеше алады. ТYЙiндi свздер: ттс, тiгiс материалдары, регенерация
Вестник Ка^ЖМУ №4-2018
Д.А. Абильдаев, Ж.А. Семжанова, Л.Ш. Абдуллаева, А.Е. Айтбердиева
Казахский Национальный медицинский университет им. С.Д. Асфендиярова, Курс Клинической Анатомии и Оперативной Хирургии
СРАВНИТЕЛЬНАЯ ХАРАКТЕРИСТИКА СОВРЕМЕННОГО ШОВНОГО МАТЕРИАЛА
(ОБЗОР ЛИТЕРАТУРЫ)
Резюме: Каждая хирургическая операция требует использования адекватного шовного материала с учетом общего состояния и возраста пациента, наличия инфекции и воспалительного процесса, высокого риска тромбоза и так далее. Таким образом, одной из проблем, определяющих дальнейший прогресс современной медицины, является создание шовных материалов, наиболее рациональных в той или иной хирургической ситуации. В данной статье авторы выполнили обширный обзор литературы по современным шовным материалам, используя онлайн библиотеки, такие как Pubmed, Google Scholar, Cochrane Library.B заключение авторы отметили, что рассмотренные шовные материалы имеют свои преимущества и недостатки, и существующие знания об их характеристиках способствуют тому, что хирурги могут выбрать подходящий материал в зависимости от типа ткани и вида операции. Ключевые слова: шов, шовный материал, регенерация
