CC BY
3
Shirinova M. G.
Sherbekova F. U.
Musinova I. O.
Samarkand State Medical Institute
CLINICAL AND BIOCHEMICAL EVALUATION OF THE EFFECTIVENESS OF COMPLEX TREATMENT OF CATARRHAL GINGIVITIS DISEASES WITH A HERBAL PREPARATION, INFUSION
OF "CLOVE TREE"
Catarrhal gingivitis is a periodontal disease characterized by serous (catarrhal) inflammation of gums. Local changes in catarrhal gingivitis include edema, hyperemia (or cyonoticity) of the gingival mucosa, soreness and bleeding margin, the presence of dental plaque, and an upleasant taste in the mouth.
It is very important at an early stage in the development of inflammatory periodontal diseases to achieve a persistent and long term effect and prevent the development of destruction processes in the periodontal tissues. Since already at a young age, due to the influence of various factors in the oral cavity, there are initial manifestations of periodontal inflammation.
Key words: catarrhal gingivitis, periodontal disease, complex treatment, herbal infusion, "Clove tree ".
In practical dentistry, complex treatment of inflammatory and destructive periodontal diseases is most often carried out with the use of antibacterial agents. However, their long-term, uncontrolled use leads to numerous complications: drug tolerance, weakening of the therapeutic effects, dysbiosis of the oral cavity and gastrointestinal tract and etc. Such complications can be avoided by using homeopathic remedies. The most promising today is the use of herbal preparations. Herbal preparations have a mild, regulating, normalizing effect. They are easily absorbed, non-toxic, do not couse side effects and allergic reactions.
The aim of study- is to evaluate the effectiveness of the use of a new generation of phytopreparations from the herbal infusion of the Clove tree in the complex treatment of catarrhal gingivitis in young patients.
Research objectives:
1. To study the dynamics of clinical changes in the state of the gums in young patients before, during and after the application of the infusion of "Clove tree" in the complex treatment of catarrhal gingivitis;
2. To study the activity of the enzymes glutathione peroxide, superoxide dismutase alanine aminotransferase, aspartate aminotransferase, lactate dehydrogenase and alkaline phosphatase in mixed saliva in young patients before, during and after the application of the infusion of "Clove tree";
3. To propose an optimal scheme for the complex treatment of young patients with inflammatory periodontal diseases of a herbal preparation, an infusion of "Clove tree";
Research materials:
Young patients with catarrhal gingivitis (40 patients). All examined patients were devided into two groups, depending on the treatment. All patients participating in our study were examined using basic (clinical) and additional (paraclinical) methods. The main (clinical) methods of examination of the patients included the collection of anamnesis of the disease and life of the subject, examination and assessment of this periodontal status. Of the additional methods of examining patients, biochemical (laboratory), functional (assessment of the state of the microvasculatory of the gums) and X-ray were used. One group underwent a standart method of treating catarrhal gingivitis, the other a complex treatment with the addition of a herbal infusion "Clove tree".
Research methods:
1. Clinical examination
2. Biochemical examination
3. Statistical data processing
Reaserch results: Our studies revealed that the GPO activity in the SS in Patients with CG of both groups was 10.73 ± 0.19 IU / ml and 10.7 ± 0D7 IU / ml, respectively. This significantly exceeded the activity of GPO in the SS in patients of the control group.GPO appears in the SS only with bleeding of the gums, therefore in t he control group in payients with a healthy periodontal condition, the GPO activity was low - 0.34 ± 0.03 IU / ml, which is consistent with other authors.
In patients with CG og the comparison group, the decrease in GPO activity was on average 17.75%, which, as in the patients of the main group, reflected in the clinical state, however in this case, it did not reach control group.
Thus, our study of the results of treatment of patients with CG indicates that professional oral hygiene, supplemented by correctly performed individual hygiene measures, is not enough for long-term and persistent relief of the symptoms of the disease. The use of herbal preparations the infusion of "Clove tree" provided a pronounced and persistent therapeutic effect for a long time.
Conclusion:
Compherensive examination of the periodontal condition in patients aged 18 to 44 years, including the determination of dental indices and indicators of mixed saliva, revealed periodontal pathology in 80%. The clinical effect of the complex application of the Clove tree infusion is confirmed by a decrease in the activity of lactate dehydrogenase in mixed saliva in patients with catarrhal gingivitis (from 133.2 ±4.68 IU / l to 102.9 ± 5.13 / IU /l) and a decrease in activity alanine aminotransferase, aspartate aminotransferase and alkaline phosphatease in the mixed saliva of the patients of the main group to the values in the control group 30 days after the start of treatment.
Significant decrease in the amount of lactoferrin in mixed saliva in patienys with chronic generalized catarrhal gingivitis 8.81 ± 0.54 ng / L to 2.88 ± 0.51 ng / L and from 7.94 ± 0.41 ng / L to 2.86 ± 0.49 ng / L, respectively confirms the anti-inflammatory effect of the infusion " Clove tree".
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