CC BY
7B-P-3
BIOMEDICAL PHOTONICS
Bimodal Fluorescence Imaging of Bladder Cancer
N. Kalyagina1'2'*. D. Kustov1, E. Kozlikina1'2, A. Borodkin1'2, M. Loshchenov2, D. Yagudaev3
1-Prokhorov General Physics Institute of the Russian Academy of Sciences, 119991, Moscow, Vavilov Str. 38, Russia 2- National Research Nuclear University MEPhI, 115409, Moscow,Kashirskoe Sh., 31, Russia 3- Central Clinical Hospital, Russian Railways-Medicine, 129128, Moscow, Budayskaya Str. 2, Russia
*Nina.Kalyagina@gmail.com
Early diagnosis of pathological cancerous micro-areas with their subsequent removal is highly important and can be achieved by the development of new modeling techniques and conducting relevant experiments. In order to study visualization properties at fluorescence endoscopy, bimodal fluorescence imaging was performed. Two-channel video fluorescence system was used as an instrunent to perform the measurements and visualization. Intraoperative images of the bladder wall were obtained in a patient with bladder cancer. A video system was used to reveal and image pathological areas with increased fluorescence intensity. Fluorescence indices in tumor tissue were recorded and corresponded to different concentrations of PpIX photosensitizer. The obtained images and fluorescence intensity measurements showed the ability of the video fluorescence system to register bladder wall structures and accumulated in them photosensitizers in different concentrations. The results of the diagnosic study allowed a doctor to reveal the tumor bodreds and new inconspicuous foci.
ALT'22
