Научная статья на тему 'Accompanying defects of development in children with congenital cleft of lip and palate'

Accompanying defects of development in children with congenital cleft of lip and palate Текст научной статьи по специальности «Клиническая медицина»

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European science review
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children / congenital cleft / defects of development / lip and palate

Аннотация научной статьи по клинической медицине, автор научной работы — Shamsiyev Jamshid, Shamsiev Ravshan

For the examination and correction 122 patients with congenital cleft of lip and palate were in the clinic № 2 of SamMI during 2004–2014. In combination of pathology the child was examined by particular specialists. Detected in children with cleft of upper lip and palate external stigma of disembryogenesis — congenital defects of development of extremities, kidneys and other changes of organs have systemic character, progress which is conditioned with dysplasia of connective tissue. For extension of complex aid and provision complete rehabilitation of patients with congenital cleft of lip and palate is necessary synchronic work of specialists.

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Текст научной работы на тему «Accompanying defects of development in children with congenital cleft of lip and palate»

Accompanying defects of development in children with congenital cleft of lip and palate

Table 3.- Distribution of patients in the main group depending on gender, age and method of hernia repair

Method of hernia repair Gender A ge

m. w. Up to 40 40 to 60 Older than 60 Total

Autoplastic hernia repair 8 17 1 18 6 25

Mesh hernia repair 12 19 1 21 9 31

Tension free mesh hernia repair 23 13 2 32 2 36

Tension free mesh hernia repair with mobilization of rectus muscles sheaths by Ramirez 14 26 9 19 12 40

Total 57 75 13 90 29 132

Table 4. - Distribution of patients in the control group depending on gender, age and method of hernia repair

Method of hernia repair Gender A ge

m. w. Up to 40 40 to 60 Older than 60 Total

Autoplastic hernia repair 12 28 5 27 8 40

Mesh hernia repair 18 30 7 26 15 48

Tension free mesh hernia repair 3 5 1 5 2 8

Total 33 63 13 58 25 96

Conclusions. Thus, the Mark score criteria of perioperative the optimal method of hernia repair based on individual character-risk in patients with incisional ventral hernias allows you to choose istics of the organism and to improve treatment outcomes.

References:

1. Аббасзаде Т. Н., Анисимов А. Ю. Диагностика и профилактика ранних послеоперационных раневых осложнений у больных с большими вентральными грыжами//Медицинский вестник Башкортостана. - 2013. - Т. 8. - №. 3.

2. Кукош М. В., Власов А. В., Гомозов Г. И. Профилактика ранних послеоперационных осложнений при эндопротезировании вентральных грыж.//Новости хирургии - 2012.- Том 20. - № 5. - С. 32-37.

3. Лаврешин П. М., Гобеджишвили В. К. Дифференцированный подход к лечению послеоперационных вентральных грыж//Вестник экспериментальной и клинической медицины. - 2014. - №. 3. - С. 246-251.

4. Shamsiyev Azamat, Kurbaniyazov Zafarjon and Davlatov Salim. "Criteria's of choice method in surgical treatment of patients ventral hernia with concomitant obesity". European science review No. 3-4. - 2016.

5. Breuing K. et al. Incisional ventral hernias: review of the literature and recommendations regarding the grading and technique of repaid/Surgery. - 2010. - Т. 148. - No.. 3. - С. 544-558.

6. Dietz U. A. et al. Importance of recurrence rating, morphology, hernial gap size, and risk factors in ventral and incisional hernia classification/Hernia. - 2014. - Т. 18. - No. 1. - С. 19-30.

7. Fink C. et al. Incisional hernia rate 3 years after midline laparotomy//British Journal of Surgery. - 2014. - Т. 101. - №. 2. - С. 51-54.

8. Shamsiev A. M., Davlatov S. S. Хирургическое лечение больных вентральными грыжами с сопутствующим ожирением//Шпитальна хiрургiя. Журнал iменi ЛЯ Ковальчука. - 2016. - No. 1.

9. Slater N. J. et al. Criteria for definition of a complex abdominal wall hernia//Hernia. - 2014. - Т. 18. - No. 1. - С. 7-17.

DOI: http://dx.doi.org/10.20534/ESR-17-1.2-155-157

Shamsiyev Jamshid, Samarkand State Medical Institute, doctor degree in medicine, department of pediatric surgery

E-mail: shamsievja@mail.ru Shamsiev Ravshan, Samarkand state medical institute, resident graduate 2st year students, specializing in maxillofacial surgery

E-mail: ravuz@yahoo.com

Accompanying defects of development in children with congenital cleft of lip and palate

Abstract: For the examination and correction 122 patients with congenital cleft of lip and palate were in the clinic № 2 of SamMI during 2004-2014. In combination of pathology the child was examined by particular specialists. Detected in children with cleft of upper lip and palate external stigma of disembryogenesis — congenital defects of development of extremities, kidneys and other changes of organs have systemic character, progress which is conditioned with dysplasia of connective tissue. For extension of complex aid and provision complete rehabilitation of patients with congenital cleft of lip and palate is necessary synchronic work of specialists.

Section 8. Medical science

Keywords: children, congenital cleft, defects of development, lip and palate.

Introduction. To the most widespread of congenital defects of development refers congenital cleft of upper lip and palate. The birth rate of children with the fact of defect is composed of about 86% anomalies of jaw-facial area and 20-30% defects of development of man [9]. Basically clefts of lip and palate are considered polygenic multifactoral diseases. They may occur as isolated defect of development and was been one of the symptoms of congenital syndromes (syndrome Van-der-Vud, Pier Robin and others). Besides, in majority of sick children with congenital clefts of lip and palate are occurred accompanying congenital defects of development of other organs and system (heart, lungs, kidneys and others), and it is also important to take into consideration in forming plan of treatment. Immediately, after birth of a child with these anomalies of development in maternity hospital is established exact clinic-anatomical diagnosis and determined the plan of surgical and conservative treatment. In case of need child is moved to the surgical department of newborns where is carried out examination, revealed congenital defects of development of other organs and system, diagnosed accompanying somatic and nervous diseases [1; 7; 8]. In the presence of accompanying defects of development, severe somatic diseases, diseases of central nervous system the time of surgical treatment are separated. Surgical rehabilitation must be finished not later 5-6 years with that estimation that the child can go to ordinary school [1; 7]. Children with Daun, Little, children cerebral paralysis and other rough pathology of organism on contraindications may be operated in later estimations [1; 2; 5]. Therefore, in the period new birth is composed ofindividual plan ofpreparation ofpatient to the surgical operation with taking into consideration of gravity of defect of development in the maxillary-facial area accompanying defects and somatic status condition of the child [4; 6; 7].

Materials and methods. For the examination and correction 122 patients from them with congenital cleft oflip — 68 (55.74%), palate- 13 (10.66%), one-sided- 96 (88.07%), two-sided- 13 (11.93%) patients, girls- 47 (43.12%) and boys accordingly-62 (56.88%) were in the clinic № 2 of SamMI during 2004-2014. 54 patients from them complete cleft of palate -52 (96.30%), with incomplete- 2 (3.70%), girls-19 (35.19%), boys — 35 (64.81%) were with non closure palate. In primary referencing these children was carried out complete clinic-laboratory examination including clinical, laboratory and instrumental examinations of patients with examination of qualified specialists such as jaw-facial surgeon, INT doctor, geneticist, orthopedist, pediatrician in necessarily neurologist, hema-tologist and orthopedist-traumatologist. Carried out research was showed that the children with congenital cleft of upper lip and palate accompanying defects of development were registered in the area of head, neck, extremities and trunk and were often combined [3; 5]. The main of them were short frenum of lip and tongue in 76 patients, low index ofbody weight in 97, deformation ofvertebra in 6, club-foot in 19, congenital flat-foot in 5, congenital dysplasia of hip joint in 2, defects of development of urinary system in 19, prenatal encephalopathy in 46, congenital muscular wryneck in 15 children. In the process of research the functions of kidneys were established pyuria in 19 children with congenital cleft of upper lip and palate. These patients were carried out special urological examination in which was revealed congenital stricture of prerenal (8) and pelvic area of urethra (6) was carried out ultrasound examination of urinary system. On evidence of excretion urography in 14 patients were revealed pyelcctasis, in 8 hydronephrolic transformation from the direction of urethra obstruction. Cystic-urethral reflux II degree

as manifestation of congenital dysplasia stoma of urethra was established in 5 children. In combination of pathology the child was examined by particular specialists (neurologist, endocrinologist, cardiologist and others), were carried out suitable recommendations, in the case of need was carried out treatment. The children with accompanying defects of development of extremities and congenital muscular wryneck after training features of nursing and feeding, examination of orthodontist and making of obturator for closing of palate defects during feeding were directed for treatment to the orthopedist-traumatologist before cheilorhinoplasty that is till three-four months of age.

Psychoneurologist carried out medico-pedagogical rehabilitating measures with parents and then with patients about medicamen-tal corrective therapy, psychotherapy. All children without exception were examined by neurologist; in the case of need they were taken electroencephalographically examination. Children with encepha-lopathy got adequate treatment till I stage of operation and further was carried out prophylaxy, observation and the treatment of the specialist [6; 7; 10]. After made diagnosis and type of hereditary transmission (in the presence of the same) by geneticist were prognosticated the degree of birth risk in proband or members of his family of other children with CCL and P. It was carried out by the orthodontist ensuring full feeding of child (obturators, disjunctive plastics and etc.), pre- and post-orthodontic treatment, notice and treatment of secondary deformation of tooth-jaw system, restoration of tooth set. Periods of active observations by doctor-orthodontist are: new born period, before and after operation, changeable bite period, and further systematically observation till complete formation of permanent bite [6; 7; 11]. Logopedist carried out logopedic treatment before and after uranoplastics, training of muscular structure of soft palate, pharynx wall, the development of speech respiration, pre-and post-operative logopedic treatment, development ofphonemic hearing, formation of connected speech. Periods of active observation of logopedist are periods in 1-2 years, 4-5 years and further 7-13 years. It has been carried out estimation of somatic status by the pediatrician individually chosen type of feeding and volume of nutrition, evaluated micro flora of oral cavity, immune status, carried out prophylaxy and in the case of need anemic treatment, rickets and hypotrophy, realized preparation for surgical treatment during the first year. These children were actively observed prophylaxy by ENT doctor taking into consideration that the possibility of hit of food from oral cavity to nasal and pharyngonasal cavity may result in to the development of chronic rhinitis, eustachitis, otitis and as consequence to the reduce of hearing. Even in the absence of evident complaints to the function of cardiovascular system, once-only elec-trocardiographically research in 74 (60.66%) children with congenital cleft of lip and palate was revealed disturbance of automatism function, myocardial, because of which the patients were examined by cardiologist and got preoperative corrections of disturbances. Success of surgical treatment in majority of patients depended on timely conduction of complex preparation in conditions of dispensary observation [7; 12]. Surgical treatment began from 3 months in satisfactory somatic and neurological status. Heading and coordinating the work of doctors-consultants the surgeon-dentist determined data and volume of surgical treatment, controlled timeliness referral children to the consultation of particular specialists and carrying out prophylactic treatment, together with them determined absolute and relative contraindication to the operation. It shouldn't forget in decision of question operation dates and higher responsibility of

Characteristic features of physical development of newborns born by mothers with pre-eclampsia

pediatrician giving permission to the surgical treatment. His conclusion about contraindication or indication to the operation of a child having accompanying CDD or somatic diseases, the pediatrician confirmed conclusions of particular specialists (cardiologist, ne-phrologist, urologist, neurologist, pulmonologist, endocrinologist and others). Absolute contraindication to the operation is insufficiency of blood circulation IA and IIB degrees. Relative contraindications are: sharp evident dystrophic changes in myocardium, acute somatic and infectious diseases and not earlier 2 months after recovery hypotrophy I-III degrees, rickets I-III degrees in fastigium period, atopic dermatitis in the stage of recrudescence, anemia with containing of erythrocytes less 3.5x10 12/l, hemoglobin less 120g/l, colored finding less 0.75, chronic diseases during 6 months after recrudescence, chronic nephritis with manifestations of renal insufficiency, dermatitis and eczema in the facial area, affection of mu-cousa. Children with relative contraindications were carried out specific treatment accompanying pathology (in the out-patient or profile departments) and on favorable dynamic was allowed opera-

tive treatment [7; 10]. But in consideration of earlier address to the specialized medical aid from the first days of the life and timely diagnostics of accompanying defects of development, primary cheilo-rhinoplasty were carried out at the age of 2-3 months, but qualified surgical treatment of children with congenital cleft of upper lip and palate was finished during 12-16 months of life.

Conclusions. Detected in children with cleft of upper lip and palate external stigma of disembryogenesis — congenital defects of development of extremities, kidneys and other changes of organs have systemic character, progress which is conditioned with dysplasia of connective tissue. For extension of complex aid and provision complete rehabilitation of patients with congenital cleft of lip and palate is necessary synchronic work of specialists: geneticist, logo-pedist, hematologist, otorhinolaryngologist, orthodontist, pediatrician, psychiatrist, orthopedist, surgeon, for timely detection of accompanying defects of development and diseases with the purpose of conduction of full, active preoperative preparation and qualified staged correction of all defects of development.

Refernces:

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2. Andreeva O. A. "Staged rehabilitation of children with congenital cleft of upper lip and palate"//Bulletin of Chuvash University -2012. - No 3. - C. 269-275.

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5. Epker B. N. Secondary surgery to correct CLP nasal deformity//3 th Biennial World Congress International Cleft Lip and Palate Foundation. Halifax. - 2004. - P. 66.

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7. Leslie E. J., Marazita M. L. Genetics of cleft lip and cleft palate//American Journal of Medical Genetics Part C: Seminars in Medical Genetics. - 2013. - T. 163. - No. 4. - C. 246-258.

8. Mossey P. A., Modell B. Epidemiology of oral clefts 2012: an international perspective//Cleft Lip and Palate. - Karger Publishers, -2012. - T. 16. - C. 1-18.

9. Neville B. W. et al. Oral and maxillofacial pathology. - Elsevier Health Sciences, - 2015.

10. Stuppia L. et al. Genetics of syndromic and nonsyndromic cleft lip and palate//Journal of Craniofacial Surgery. - 2011. - T. 22. - No. 5. - C. 1722-1726.

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DOI: http://dx.doi.org/10.20534/ESR-17-1.2-157-158

Ergashbaeva Dilrabo Abdurasulovna, The Head of the Chair of Neonatology, the Faculty of Doctor's Advanced Courses, ASMI Nasirova Feruza Djumabaevna, PhD the chair of obstetrics and gynecology ASMI Azizov Uriy Dalievich, The Head of the ChairMicrobiology, doctor of science, professor

Characteristic features of physical development of newborns born by mothers with pre-eclampsia

Abstract: Characteristic features of anthropometric indices of 100 new-borns born by women with pre-eclampsia (PE) according to their postnatal gestation age, in comparison with 30 children born by women without sign of PE and extra genital diseases were described in this work. The conclusion was that among the children born by women with pre-eclampsia (PE) there were immature children (full term and non-full term); their objective evaluation imitates the clinics of hypoxic ischemic encephalopathy and its complications.

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