Клиническая медицина список научных статей
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The Role of the Akt Signaling Pathway in Sjögren’s Syndrome
Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disorder with diverse clinical picture and high prevalence of B-cell non-Hodgkin lymphoma (NHL), that possibly raises from the chronic activation of B-cells. The mechanisms underlying the development of neoplasia in pSS remain elusive....
2023 / Efstathia K. Kapsogeorgou, Ioanna E. Stergiou, Loukas Chatzis, Michael Voulgarelis, Panayiotis G. Vlachoyiannopoulos -
‘Ray Pattern’ of Hand Joint Involvement2023 / Sankar J, Jithin Mathew, Sanjay Jain, Varun Dhir
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Symptomatic Bilateral Sacroiliitis in a Patient with Juvenile Systemic Lupus Erythematosus: A Rare Association2023 / Vikas Gupta, Devinderpal Singh Dhanota
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Thyroid Storm in Lupus: A Rare Cause of Unrelenting Pyrexia
Systemic lupus erythematosus may present with fever, and it is a challenge to attribute fever to a particular cause. Very rarely it can be due to hyperthyroidism. Thyroid storm is a medical emergency causing unrelenting pyrexia. Here we report a case of a young female who first presented as fever...
2023 / Varsha R. Bhatt, Sanjay M. Khaladkar, Manaswini Edara -
Prevalence & Impact of COVID-19 in Systemic Sclerosis Patients and Assessment of the Demographic & Clinical Features in Cases Associated with Worse Prognosis: Results of a Single Centre Registry
Background: Our knowledge of the COVID-19 infection impact on systemic sclerosis (SSc) is scarce. This study aimed to assess the prevalence of COVID-19 infection and to determine the predictive factors of worse outcomes and death in SSc patients. Methods: In this cohort study all patients who...
2023 / Hadi Poormoghim, Fatemeh Gaffarirad, Shahrzad Rahmani, Negin Mohtasham, Simin Almasi, Ali Sobhani, Μaryam Salimi-Beni, Elham Andalib, Parsa Amiri Naeini, Arash Jalali -
Recommendations of the Moroccan Society of Rheumatology (SMR) for the Therapeutic Management of Spondyloarthritis (SpA) including Psoriatic Arthritis (PsA)
The advent of new therapeutic classes and the updating of international recommendations have justified the development of recent recommendations by the Moroccan Society of Rheumatology. Methods Guidelines were drafted by a core steering committee after performing a literature search. A...
2023 / Nada Jaouad, Lamia Oulkadi, Ibtissam Bentaleb, Ahmed Bezza, Abdellah El Maghraoui, Redouane Niamane, Imane El Bouchti, Saloua Larhrissi, Linda Ichchou, Saadia Janani, Fatima Ezzahra Abourazzak, Nessrine Akasbi, Mariam Erraoui, Samia Karkouri, Ihsane Hmamouchi, Rachid Bahiri -
Anti-IL5 Monoclonal Antibodies Reduce Asthma Exacerbations and Corticosteroids Dose in Three Eosinophilic Granulomatosis with Polyangiitis Case Reports
Eosinophilic Granulomatosis with Polyangiitis (EGPA) is a rare multisystem necrotizing small and medium-sized vessel vasculitis with eosinophilic adult-onset asthma as part of its spectrum. Therapeutic choices include corticosteroids, immunosuppressive agents, and novel immunomodulators....
2023 / Elpida Skouvaklidou, Maria Kipourou, Dimitrios Zisopoulos, Periklis Vounotrypidis, Konstantinos Katsoulis -
Clinical and Serological Characteristics of a Monocentric Cohort of Patients Affected by Interstitial Pneumonia with Autoimmune Features (IPAF)
Introduction: Interstitial lung diseases (ILDs) are diseases characterised by excessive deposition of collagen matrices in the pulmonary interstitium. Some of them are considered idiopathic (idiopathic pulmonary fibrosis – IPF), others are related to known pathologies such as connective tissue...
2023 / Claudia Canofari, Andrea Vendola, Annamaria Iuliano, Loreta Di Michele, Alfredo Sebastiani, Andreina Gubbiotti, Gian Domenico Sebastiani -
Physical Therapists’ Choices, Views and Agreements Regarding NonPharmacological and Non-Surgical Interventions for Knee Osteoarthritis Patients: A Mixed-Methods Study
Objective/Aims: The aims of this study are to collect the most common non-pharmacological and non-surgical interventions used by the Portuguese physical therapists in their knee osteoarthritis patients, and to deeper understand the factors associated to their intervention choices. Methods: This...
2023 / Ricardo M. Ferreira, Pedro N Martins, Nuno Pimenta, Rui S. Gonçalves -
Limbic Encephalitis as a Late Complication of Relapsing Polychondritis: A Case Report and Review of the Literature2023 / Vasiliki Michalaki, Dimitrios Katsifis-Nezis, Tzim Rallis, Konstantinos Kanavouras, Zisis Tsouris, Andromachi Roussopoulou, Maria Ismini Arvaniti, Anastasia Skafida, Smaragdi Katsoulakou
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Spinal Tuberculosis: Features and Early Predictive Factors of Poor Outcomes
Introduction: Tuberculosis is still endemic in Tunisia. Among musculoskeletal involvement, spinal tuberculosis (STB) or «Pott’s Disease» is the most common and can lead to serious neurological complications. The purpose of our study was to focus on STB features (clinical, biological, and...
2023 / Soumaya Boussaid, Mariem M’Rabet, Sonia Rekik, Samia Jammali, Safa Rahmouni, Khaoula Zouaoui, Hela Sahli, Mohamed Elleuch -
Nakajo-Nishimura Syndrome: The First African Case
Nakajo-Nishimura syndrome is a hereditary autoinflammatory disorder caused by an autosomal recessive homozygous mutation of the PSMB8 gene, which encodes the immunoproteasome subunit beta 5i. The clinical manifestations of NNS are mainly pernio-like skin rashes, nodular erythema, lipodystrophy,...
2023 / Nacif Eddine Ghodbane, Ali Mecibah, Zohra Merzougui, Halima Zerguine, Zineb Akakba, Samy Slimani -
Focal Segmental Glomerulosclerosis and Hyalinosis in a Patient with Spondyloarthritis: A Rare Renal Involvement Case Report
Background: During its course, spondyloarthritis (SpA) may be associated with extra-articular manifestations affecting several organs. Renal involvement is one of the most common extra-articular manifestations and is dominated by secondary amyloidosis (AA), immunoglobulin A (IgA) nephropathy, and...
2023 / Soumaya Boussaid, Houssem Tbini, Sonia Rekik, Ikram Mami, Lilia Ben Fatma, Samia Jammali, Hela Bargaoui, Hela Sahli, Lamia Rais, Mohamed Karim Zouaghi, Mohamed Elleuch -
Pulmonary-Renal Syndrome During COVID-19 Pandemic Revealed a Rare Case of Anti-GBM Disease
Anti-GBM disease is a rare, life-threatening small vessel vasculitis caused by circulating anti-GBM antibodies resulting to rapidly progressive glomerulonephritis and/or pulmonary haemorrhage. The gold standard for the diagnosis is the renal biopsy with the pathognomonic finding of linear...
2023 / Aglaia Chalkia, Christos Koutsianas, Emelina Stampolliou, Panagiota Giannou, Harikleia Gakiopoulou, Dimitrios Vassilopoulos, Dimitrios Petras -
Case Series on DRESS: An Unpredictable Adverse Drug Reaction
Drug rash with eosinophilia and systemic symptoms syndrome (DRESS) is a potentially lifethreatening, drug-induced, multi-organ system reaction. The most frequently involved organ is the liver, followed by the kidneys and lungs. Early detection and diagnosis followed by withdrawal of the offending...
2023 / Maryam Fatima, Salwa Sahar Azimi, Soumya Ashwini, Madhuri H Radhakrishna -
Chilblain Lupus2023 / Ge Vivin Vinister, Rashmi Roongta, Debanjali Sinha, Arghya Chattopadhyay, Sumantro Mondal
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Successful Use of Tofacitinib in Scleroderma Arthropathy
Musculoskeletal manifestations of systemic sclerosis (SSc) are frequent and may be one of the early manifestations of the disease. However, arthralgia, pain and stiffness without frank arthritis usually constitute the clinical picture, while overlap syndromes such as rheumatoid-like polyarthritis...
2023 / Prakashini Mv, Debashis Maikap, Prasanta Padhan -
Paraneoplastic Polyarthritis in a Patient with Synchronous Lung and Colorectal Malignancy
Arthritis is an unusual manifestation of paraneoplastic syndrome, appearing in a variety of cancers, including pulmonary and colorectal. It can often pose a diagnostic challenge to physicians, since it may be difficult to distinguish from more commonly encountered rheumatic illnesses. Moreover,...
2023 / Claudia Cobilinschi, Alexandra Constantinescu, Egor Șargarovschi, Simona Enache, Andra Rodica Bălănescu, Daniela Opriș-Belinski -
SARS-CoV-2 Infection-Induced Necrotising Sarcoid Granulomatosis
SARS-CoV-2 infection is a pandemic that affects predominantly upper airways and lungs. It may lead to reactivation of known inflammatory rheumatic diseases and/or initiation of various granulomatous disorders. Necrotising sarcoid granulomatosis (NSG) is a rare condition that can be confused with...
2023 / Aysu Sinem Koc, Neslihan Fener, Senol Kobak -
Periodontal Disease in Patients with Newly Diagnosed Systemic Lupus Erythematosus
Statement of the Problem: Most of the studies assessing the relationship between systemic lupus erythematosus (SLE) and periodontal disorder are focused on patients with previously diagnosed SLE whose periodontal hygiene may be influenced by immunosuppressive therapies. Purpose: This study aimed to ...
2023 / Maryam Sahebari, Farzaneh Latifian Allaf, Nahid Nasrabadi, Ala Ghazi, Mandana Khodashahi, Fateme Absalan, Pegah Mosannen Mozafari, Shaghayegh Abbasi