Фундаментальная медицина список научных статей
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INVESTIGATING METHODS OF EXTRACTING BIOACTIVE COMPOUNDS FROM MANDRAGORA TURCOMANICA PLANT
Mandragora is a mountain medicinal plant is known to mankind since ancient times. The plant is also known as selmelek, mehrigoya, serayot, or the herb of life. According to its habitat, the Turkmen mountain range grows in our country at an altitude of 800-1200 meters. It grows in clayey, improved...
2024 / Igdirova P., Geldimyradova Ch., Soltanova N. -
ИММУНОЛОГИЧЕСКИЕ ИЗМЕНЕНИЯ У ПАЦИЕНТОВ С ХРОНИЧЕСКОЙ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТЬЮ
Хроническая сердечная недостаточность симптомокомплекс, возникающий в исходе сердечно-сосудистых заболеваний различной этиологии. В настоящий момент сердечная недостаточность широко распространена и приобрела характер пандемии. Данный факт привел к необходимости уточнения известных механизмов...
2018 / Купенов Б.Г., Малгаздарова О.В., Молдажанова А.М., Бекжигитова Ж.Б. -
МАРКЕРЫ ОКИСЛИТЕЛЬНОГО СТРЕССА КЛЕТОК КРОВИ У ПАЦИЕНТОВ С ЭКЗОГЕННЫМИ ТОКСИЧЕСКИМИ НЕФРОПАТИЯМИ
Большое количество научных работ посвящено изучению механизмов развития почечной недостаточности на фоне отравления алкоголем и уксусной кислотой. Однако связь между употреблением алкоголя и поражением почек до сих пор считается спорной, и молекулярные механизмы повреждения почек при отравлении...
2018 / Демидчик Людмила Андреевна -
МОДИФИЦИРОВАННЫЕ БЕЛКИ В КРОВИ ПАЦИЕНТОВ С ЛЕКАРСТВЕННО-ИНДУЦИРОВАННОЙ НЕФРОПАТИЕЙ
Лекарственное повреждение почек является частым неблагоприятным исходом, которое способствует росту заболеваемости и даже потере трудоспособности. Наши текущие знания о нарушении функции почек, вызванных лекарственными средствами (ЛС), ограничены ввиду различных определений повреждений почек,...
2018 / Ли Валентина Витальевна -
АУТОЛОГИЧНЫЕ СТВОЛОВЫЕ КЛЕТКИ -ПЕРСПЕКТИВЫ ЛЕЧЕНИЯ РЕЗИСТЕНТНОГО НЕФРОТИЧЕСКОГО СИНДРОМА ПРИ СИСТЕМНОЙ КРАСНОЙ ВОЛЧАНКЕ2018 / Криворучко Н.А., Туганбекова С.К., Аскаров М.Б., Иманбердиева А.М., Аманбеккызы С., Касымова Ж.А.
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ВОЗМОЖНОСТЬ ПРИМЕНЕНИЯ ПРОТОЧНОЙ ЦИТОФЛЮОРИМЕТРИИ ЛИМФОЦИТОВ ПЕРИФЕРИЧЕСКОЙ КРОВИ В ДИАГНОСТИКЕ ПОЗДНЕГО КЛЕТОЧНОГО ОТТОРЖЕНИЯ ТРАНСПЛАНТАТА ПОЧКИ2018 / Носик А.В., Коротков С.В., Смольникова В.В., Гриневич В.Ю., Калачик О.В., Кривенко С.И., Руммо О.О.
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РОЛЬ НЕЙТРОФИЛЬНЫХ ВНЕКЛЕТОЧНЫХ ЛОВУШЕК В ОНКОГЕНЕЗЕ
Представления о роли внеклеточных нейтрофильных ловушках при онкологии сильно варьируют. С одной стороны, есть данные об антиканцерогенных свойствах нейтрофильных сетей, связанных с прямым разрушением опухолевых клеток и стимуляцией иммунной системы. Цитотоксичность по отношению к опухолевым...
2019 / Маратқызы М., Косыбаева А.Е., Кабилдина Н.А., Бейсенаева А.Р. -
МЕХАНИЗМЫ ПОВРЕЖДЕНИЯ КЛЕТОК КРОВИ И ПОЧЕК ПРИ ЭКЗОГЕННЫХ ТОКСИЧЕСКИХ НЕФРОПАТИЯХ
В данной работе проводится анализ и обобщение имеющихся представлений о механизмах повреждения почек и развитии нефропатий при острых отравлениях основными экзогенными нефротоксинами. В статье рассматриваются механизмы токсического действия алкоголя, уксусной кислоты и лекарственных препаратов на...
2019 / Ли В.В., Демидчик Л.А. -
ПСОРИАЗ КЕЗІНДЕГІ ІШЕКТІҢ ТОСҚАУЫЛДЫҚ ФУНКЦИЯСЫНЫҢ РӨЛІ ЖӘНЕ ІШЕК МИКРОБИОМЫНЫҢ ЖАЙКҮЙІ
Әдебиеттерге шолуда псориаз кезіндегі ішектің жай-күйіне және микробиомның ерекшеліктеріне қатысты, сондай-ақ осы патологиядағы иммундық жүйенің рөлі туралы ең соңғы және негізгі деректер жалпыланған. Псориазбен ауырған пациенттердің ішегінде түрлі микробтық құрам болғаны анықталды, атап айтқанда...
2019 / Алгазина Т.О., Ермекбаева Б.А., Кушугулова А.Р., Кожахметов С.С., Джетписбаева З.С., Батпенова Г.Р. -
THE CLINICAL OUTCOME COMPARISON OF ISCHEMIC STROKE WITH AND WITHOUT ATRIAL FIBRILLATION
Background: Atrial fibrillation increases the risk of stroke and is associated with poor stroke outcomes. The primary concern of this study was to compare the clinical outcome of ischemic stroke patients with atrial fibrillation and without atrial fibrillation. Methods: This was a retrospective...
2019 / Rizaldy Taslim Pinzon, Fransiscus Buwana -
Genetic predisposition for the development of complications in patients after coronary artery stenting
In the review the authors analyzed the literature data on the state of knowledge of the problems of genetic polymorphisms CYP2C19 gene response to clopidogrel in patients with acute coronary syndrome. Despite on the technological advances and the widespread use of coronary stenting, restenosis at...
2019 / Dana Taizhanova, Akerke Kalimbetova, Aliya Toleuova, Roza Bodaubay, Olga Visternichan, Aigul Kurmanova -
The role of aquaporins in the regulation of body fluids homeostasis
The rapid transfer of the water across the cells occurs via specialized channels called aquaporins (AQPs). The structure of AQPs comprises of homotetramers with each of the four units functioning as an independent channel. The distribution of total body water is into intracellular (40% of total...
2019 / Olayinka Rasheed Ibrahim, Olufemi Soladoye -
Prevalence of new psychoactive substances addiction: a hospital-based cross-sectional study
Background: New psychoactive substances are a combined group of chemical substances developed in an attempt to circumvent control and restrictive measures for traditional drugs. Until 2017, the countries of Central Asia remained a gray spot on the maps of epidemiological new psychoactive substances ...
2020 / Mariya Prilutskaya, Oleg Yussopov, Nikolay Negay, Kuanysh Altynbekov, Makpal Tokayeva -
Vaccination status (PCV13) of children with pneumococcal meningitis
Pneumococcal meningitis in children is one of the reasons for the development of serious neurological complications. According to various authors, in developed countries, the incidence rate ranges from 8 to 34 cases per 100,000 population, in Kazakhstan there is no etiological interpretation of...
2020 / Aliya Seidullayeva, Dinagul Bayesheva, Bayan Turdalina, Alyona Altynbekova, Aliya Omarova, Meruert Khamitova, Sabit Tashenov, Aislu Otarbayeva, Samat Kozhakhmetov -
Matrix metalloproteinases genes polymorphism in the development of new cardiovascular events
The review article presents a study of the literature on the relationship of gene polymorphism of matrix metalloproteinases (MMP 2 (−1575 G>A), MMP3 (−1171 5A/6A), MMP 9 (−1562 C/T) with the risk of developing new cardiovascular events after percutaneous coronary intervention. To achieve this goal, ...
2020 / Dana Taizhanova, Akerke Kalimbetova, Ainur Akilzhanova -
Validated stability Spectrophotometric process for estimation vancomycin antibiotic degradation behavior in pharmaceutical kinds
Objective: To estimate the dissolution behavior of the antibiotic vancomycin hydrochloride in pharmaceutical formulations, a novel, quick as well as innovative stabilization implying spectrophotometric process has been created and certified. Using the spectrophotometric process to calculate the...
2020 / Mohauman Mohammed Majeed Al-Rufaie -
Association between A1298C and C677T methylenetetrahydrofolate reductase gene polymorphisms and the risk of acute lymphoid and myeloid leukemia
Background: Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme involved in folate metabolism, DNA methylation and synthesis. Two MTHFR polymorphisms, C677T and A1298C, have been associated with reduced enzyme activity. Rapidly replicating cell types, such as hematopoietic cells, may be...
2020 / Yousef Mortazavi, Zahra Ghasemi, Sanaz Aghajani, Mohammad Eftekhari Shirkohy, Minoosh Moghimi, Alireza Khademolmelleh, Saeideh Mazloomzadeh -
The effect of marital status on burnout levels of nurses: A meta-analysis study
Objective: This study was planned and carried out as a meta-analysis study in order to analyze the effect of marital status on burnout levels of nurses. Material and methods: In the study, meta-analysis method, one of the quantitative research methods, was used. The keywords "Nursing", "Burnout...
2020 / Serkan Temel, Tülin Yildiz, Fatma Eti Aslan -
Knowledge, attitude and behavior towards COVID-19 among the Turkish healthcare workers
Aim: Coronavirus disease 2019 (COVID-19) cases and the number of deaths linked to this disease have been increasing day by day, turning into a global health problem. Healthcare workers play a key role in the fight against COVID-19. It is aimed to determine the level of knowledge, attitude and...
2020 / Yasin Uzuntarla, Sumeyra Ceyhan -
Epidemiology of kidney cancer in Turkistan region
Introduction: The article presents epidemiological data on the cases of kidney cancer in Turkistan region depending on age and sex. Purpose: Assess the incidence and neglect of kidney cancer in the Turkestan region. Material and methods: Mathematical and statistical methods recommended by the...
2020 / Assel Zhumagulova, Ruslan Nurbaba