Фундаментальная медицина список научных статей
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СТРЕСС-ЛИМИТИРУЮЩИЕ ЭФФЕКТЫ ПРИМЕНЕНИЯ ПИТЬЕВОЙ МИНЕРАЛЬНОЙ ВОДЫ ПСЫЖСКОГО МЕСТОРОЖДЕНИЯ КАРАЧАЕВО-ЧЕРКЕССИИ ПРИ ЛЕКАРСТВЕННОМ ПОРАЖЕНИИ ПЕЧЕНИ В ЭКСПЕРИМЕНТЕ
В статье рассмотрены метаболические механизмы проявления стресс-лимитирующих эффектов профилактического курса питьевой минеральной воды Псыжского месторождения (Прикубанский район, КЧР) на экспериментальной модели лекарственного поражения печени крыс парацетамолом. Установлены изменения уровня...
2023 / Узденов Марат Борисович, Репс Валентина Федоровна, Козлова Виктория ВячеславовнаВАК -
Overtraining Syndrome: Peculiarities and Perspectives of Diagnostics
Overtraining syndrome (OTS) is a condition associated with prolonged dysfunctional adaptation to physical exercise and a long-term imbalance between training and recovery that results in decreased sports performance lasting from several weeks to months with serious consequences for the health of...
2023 / Yu.I. Brel, Ya.I. Faschenko, S.N. Melnik -
Search for Associations of Mitochondrial Genome Polymorphisms with Type 2 Diabetes Mellitus in the Sakha (Yakut) Population
The Republic of Sakha (Yakutia), located in the northeastern part of Russia, is characterized by an extremely cold climate, to which the indigenous people is adapted. Over the past decades, there has been a significant increase of the incidence of type 2 diabetes mellitus (T2DM) among the...
2023 / D.G. Tikhonov, R.N. Zakharova, T.M. Sivtseva, M.V. Golubenko, S.I. Semenov, L.A. Sydykova, M.M. Afanasiev, S.A. Fedorova, V.L. Osakovsky -
The Effect of 1,2,4-trioxolanes with Betulin in Fish Oil on Oxidative and Energy Metabolism Under Hypoxia and Immobilization Stress in Rats
1,2,4-trioxolanes were obtained by the ozonation of fish oil with a mixture of oxygen and ozone to study their physicochemical properties. The biological activity of 1,2,4-trioxolanes with betulin from birch bark extract in fish oil was evaluated under hypoxia and immobilization stress in rats....
2023 / N.B. Melnikova, D.S. Malygina, P.V. Yastrebov, I.V. Spitskaya, A.G. Soloveva, A.E. Fayans, A.L. Esipovich -
Regulation of Calcium Homeostasis in Microglia: Current View on the Pathogenesis and Correction of Neuroinflammation
The focus of this review is on evaluating the contribution of various regulatory mechanisms of calcium metabolism to the execution of key microglial functions such as patrolling, migration, proliferation, polarization, as well as mitochondrial plasticity and inflammasome assembly. We address...
2023 / A.K. Berdnikov, D.A. Atyakshin, L.V. Nikolaeva, A.B. Salmina -
The Influence of BDNF on Anhedonic Behavior in an In Vivo Model of Chronic Unpredictable Mild Stress
Depression is a significant global medico-societal concern. The serotonin system plays a pivotal role in modulating responses to acute stress and is implicated in the development of depressive and anxiety disorders. Recent research has increasingly focused on the potentially beneficial impacts of...
2023 / E.V. Mitroshina, A.D. Perenkov, E.A. Karpenko, A.M. Kubareva, M.V. Vedunova -
ГЕЙМИФИКАЦИЯ В МЕДИЦИНСКОМ ОБРАЗОВАНИИ
Геймификация представляет собой применение игровых техник в неигровых процессах, как правило, с целью повышения вовлеченности обучаемого в процесс обучения. С точки зрения современного образования, игровые технологии помогают реализовывать принцип студенто-ориентированности и положительно влияют на ...
2023 / Ветлужская Мария Владимировна -
ОТКРЫТЫЕ МЕДИЦИНСКИЕ СООБЩЕСТВА КАК ЭТАП ПОСТДИПЛОМНОГО ОБРАЗОВАНИЯ ВРАЧА
Введение. Современные тренды в здравоохранении ведут к изменению роли врача и пациента. В настоящее время врач не берет на себя целиком ответственность за здоровье пациента, а выступает в роли эксперта-профессионала, способного сформировать решение у пациента. Поэтому помимо основных...
2023 / Демкина Александра Евгеньевна, Коробейникова Анна Николаевна -
ПРОЛИФЕРАТИВНО-АПОПТОТИЧЕСКИЕ ОСОБЕННОСТИ ЭПИТЕЛИЯ ТОЛСТОЙ КИШКИ ПОСЛЕ ОБЛУЧЕНИЯ ЭЛЕКТРОНАМИ В ДОЗЕ 2 ГР
Одним из основных компонентов пищеварительной системы является тонкий кишечник, в котором происходит переваривании и всасывание питательных компонентов (полостное, пристеночное, мембранное пищеварение). Радиационная терапия способна оказывать повреждающее действие на слизистую оболочку тонкой кишки ...
2023 / Каракаева Э. Б-Г., Шаповалова Елена Юрьевна, Саакян С. В., Зорин И. А., Корякин С. Н. -
ФУНДАМЕНТАЛЬНЫЕ АСПЕКТЫ БИОТРОПНОГО ВЛИЯНИЯ ФАКТОРОВ КОСМИЧЕСКОЙ ПОГОДЫ
В рамках данного литературного обзора рассмотрены, имеющиеся к настоящему времени в доступных нам литературных источниках, гипотезы, объясняющие механизмы биотропного действия факторов космической погоды. Рассматриваемые механизмы затрагивают различные уровни организации живой материи. В тексте...
2023 / Комзин Кирилл Васильевич -
“AHA!” AND “OH YES!”: HOW EMOTIONS AFFECT INSIGHT EXPERIENCE
Besides classical “Aha!” moments after successful solutions, researchers have recently examined the “Oh yes!” phenomenon, which occurs when participants are presented with ready-made answers. We investigated the influence of emotional state on insight ratings in these two situations. We propose two ...
2023 / Ekaterina А. Valueva, Nadezhda M. LaptevaScopusВАКRSCIESCI -
USING SUBJECTIVE REPORT RATING SCALES TO REVEAL BASIC PROCESSES UNDERLYING INSIGHT SOLUTIONS IN ANAGRAM TASKS
The research attempted to evaluate the informativeness of subjective rating scales in order to reveal the processes underlying insightful solving of anagrams. Subjects divided into two groups solved anagrams evaluating their own solutions using rating scales of subjective characteristics taken from ...
2023 / Alexey A. MedyntsevScopusВАКRSCIESCI -
A STUDY OF CORRELATIONS BETWEEN NEWBORN CHILDREN OUTCOMES AND EMOTIONAL STATES AND ATTACHMENT TO A FETUS IN WOMEN PREGNANT USING IN-VITRO FERTILIZATION
Children's development in the early years is significantly linked to further well-being. Among many factors involved in early development are mother’s attachment to the fetus and her emotional state during pregnancy. The current study prospectively explores mothers’ characteristics during the third ...
2023 / Tatiana G. Bokhan, Olga V. Terekhina, Marina V. Shabalovskaya, Anna V. Silaeva, Svetlana B. Leshchinskaia, Zhanna Ph. Gayfulina, Kristina V. Aparina, Sergey B. Malykh, Yulia V. KovasScopusВАКRSCIESCI -
Neurophysiological cognitive assessment and its association with neutrophil to lymphocyte ratio
Relevance. Cognition is an important physiological and higher mental functions in human being. There are various studies showing that inflammatory condition could negatively affect fronto temporal cognitive abilities such as memory, attention and executive functions. A non-invasive test P300 a...
2023 / Rajprabha, Anshul Sharma, Jitender Sorout, Sudhanshu Kacker, Naina JangidВАК -
Inflammatory response modulation by epinephrine and norepinephrine
Relevance. Inflammation is a defense response of an organism to a pathogen. It appears in order to maintain homeostasis and is regulated by the immune, nervous, and endocrine systems. The hormones epinephrine and norepinephrine are produced in the adrenal medulla and in the brain, and are universal ...
2023 / Svetlana V. Guryanova, Artem S. Ferberg, Ilya A. SigmatulinВАК -
Иммунологическое прогнозирование эффективности вспомогательных репродуктивных технологий
Высокая частота бесплодия является значимой медико-социальной проблемой многих стран мира, для решения активно применяются вспомогательные репродуктивные технологии (ВРТ). Учитывая, что в развитии и сохранении беременности важную роль играют иммунные реакции, изучение изменений иммунных параметров...
2023 / Л.В. Матвеева, Г.В. Фоминова, Е.В. Громова, Е.А. Алямкина, А.С. ГалыняВАК -
Antibacterial activity of Clove Syzygium aromaticum L. and synergism with antibiotics against multidrug-resistant uropathogenic E. coli
Relevance. Urinary tract infections pose a growing threat to humanity due to the rise of antibiotic resistance in uropathogens. Exploring natural sources for alternative treatments has become a prominent approach. The aim of the research was to investigate the antibacterial effects of clove...
2023 / Razan Marouf, Andrey A. Ermolaev, Irina V. Podoprigora, Alexander N. Senyagin, Manga J.A. MbargaВАК -
Decomposition of individual components of bioorganic waste: volatile organic compounds and the impact on health and psychoemotional state
The study considers the impact on the person’s health and psycho-emotional state of unpleasant odors arising from the storage and accumulation of bioorganic waste, including food waste (meat, poultry, fruits and vegetables) and bird droppings. The survey data of poultry and livestock farms’...
2023 / Marianna D. Kharlamova, Mikhailo Adamovich, Kseniya S. Romanovskaya, Mikhail A. Spirin, Lana R. Mustaeva, Nikolay AdamovichВАК -
Pathomorphological analysis of the gum tissues in the application of the combination of Soderm®Forte gel with Cytoflavin® in experimental periodontitis in rats
Introduction: Periodontitis is one of the most urgent problems of modern dentistry. The development of new paradigms and regimens of combination therapy of patients with periodontitis is a strategic task for pharmacologists and dentists. In view of this, pathomorphological examination is of high...
2023 / Pavel A. Galenko-Yaroshevsky, Aleksandr А. Slavinskiy, Mark A. Zadorozhniy, Valeriy K. Leontev, Artur V. Kheigetyan, Viktor L. Popkov, Anait V. Zelenskaya, Lyudmila M. Chuprinenko, Aleksandr А. Verevkin, Izabella G. Lomsadze, Mariya Yu. Materenchuk, Svetlana A. Lebedeva -
First discovered positive effect of L-norvaline on the volume of small intestine tissues necrosis in a model of segmental mesenteric thrombosis in rats
Introduction: Mesenteric thrombosis is a severe pathology with necrotization of intestinal tissues and death of the patient. The development of effective pharmacotherapy is an important task facing researchers. Materials and Methods: All studies were performed on 42 female white rats of the Wistar...
2023 / Sergey A. Alekhin, Elena N. Bezhina, Dmitry P. Nazarenko, Leontiy V.Druzhikin